Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Prakash S. Masurekar"'
Autor:
Kenneth E. Wilson, Prakash S. Masurekar, Debbie L. Zink, Rosemarie Kelly, Craig A. Parish, Hao Wang, Terry Roemer, Scott K. Smith, Julian Davies, Deming Xu
Publikováno v:
Journal of Natural Products. 77:1280-1286
The Candida albicans fitness test is a whole cell screening platform that utilizes a mixed-pool of C. albicans mutants, each of which carries a heterozygous deletion of a particular gene. In the presence of an antifungal inhibitor, a subset of these
Autor:
James M. Balkovec, David L. Hughes, Sheo B. Singh, Prakash S. Masurekar, Robert E. Schwartz, Carole A. Sable
Publikováno v:
Nat. Prod. Rep.. 31:15-34
Covering: 1985 to 2001. This paper describes a fifteen year journey from concept to clinical discovery and development of the first in class caspofungin acetate (CANCIDAS®) a parenteral antifungal agent. Caspofungin is a semisynthetic derivative of
Autor:
Ignacio González, John G. Ondeyka, José R. Tormo, Jesús Martín, Hiranthi Jayasuriya, Deborah L. Zink, Kithsiri Herath, Francisca Vicente, Prakash S. Masurekar, Sheo B. Singh, Michael A. Goetz, Chaowei Zhang, Olga Genilloud
Publikováno v:
The Journal of Antibiotics. 66:599-607
Natural products have been major sources of antibacterial agents and remain very promising. Frequent rediscoveries of known compounds hampers progress of new discoveries and demands development and utilization of new methods for rapid biological and
Autor:
Chaowei Zhang, Olga Genilloud, Karen Dorso, Mary Motyl, James L. Occi, Angela Basilio, Russell Onishi, Charles Gill, Oscar Salazar, Scott K. Smith, Emily Hickey, Prakash S. Masurekar, Sheo B. Singh, Francisca Vicente, John F. Barrett, Deborah L. Zink, Sookhee Ha
Publikováno v:
Journal of the American Chemical Society. 130:12102-12110
Bacterial resistance to antibiotics, particularly to multiple drug resistant antibiotics, is becoming cause for significant concern. The only really viable course of action is to discover new antibiotics with novel mode of actions. Thiazolyl peptides
Autor:
Emily Hickey, Sheo B. Singh, Karen Dorso, Hiranthi Jayasuriya, Prakash S. Masurekar, Karen M. Overbye, John F. Barrett, Kithsiri Herath, James L. Occi, Charles Gill, Mary Motyl
Publikováno v:
The Journal of Antibiotics. 60:565-571
Thiazomycin is a novel thiazolyl peptide closely related to nocathiacin I. It was isolated from Amycolatopsis fastidiosa by chemical and biological screening. Thiazomycin showed highly potent bactericidal activity against Gram-positive pathogens (MIC
Autor:
Jon D. Polishook, Jan Sigmund, Prakash S. Masurekar, Stephen Skwish, Gary S. Kath, Gerald F. Bills, Claude Dufresne, Gregory W. King, Jesús Martín, Neal Simpson, Olga Genilloud, Fernando Pelaez, S J Siciliano
Publikováno v:
SLAS Discovery. 11:704-711
Several protocols for bacterial isolation and techniques for aerobic plate counting rely on the use of a spiral plater to deposit concentration gradients of microbial suspensions onto a circular agar plate to isolate colony growth. The advantage of a
Publikováno v:
Mycological Research. 103:179-192
The importance of pneumocandin B O as the fermentation-derived starting material for the antifungal drug candidate, MK-991, along with the identification of our production strain as Z. arboricola (ATCC 20868) as CBS prompted a search for other strain
Autor:
David F. Sesin, Ken Bartizal, Robert E. Schwartz, Deborah L. Zink, Sandra A. Morris, Thomas C. Hallada, Prakash S. Masurekar, Dennis M. Schmatz, Otto D. Hensens
Publikováno v:
The Journal of Antibiotics. 47:755-764
Pneumocandin D0 (9), a new member of the echinocandin class of antifungal agents, has been isolated as a minor constituent from fermentation broths of the filamentous fungi Zalerion arboricola (ATCC 20957). The structure of 9 has been determined main
Autor:
David F. Sesin, Otto D. Hensens, Dennis M. Schmatz, Prakash S. Masurekar, Deborah L. Zink, Ken Bartizal, Thomas C. Hallada, Sandra A. Morris, Robert E. Schwartz
Publikováno v:
ChemInform. 26
Pneumocandin D0 (9), a new member of the echinocandin class of antifungal agents, has been isolated as a minor constituent from fermentation broths of the filamentous fungi Zalerion arboricola (ATCC 20957). The structure of 9 has been determined main
Autor:
Leonard Katz, Richard H. Baltz, Prakash S. Masurekar, Lee R. Lynd, Beth Junker, Arnold L. Demain, Julian Davies, Christopher D. Reeves, Alan T. Bull, Huimin Zhao
Publikováno v:
Manual of Industrial Microbiology and Biotechnology, Third Edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3ed48a1f1ca4c52ca212f877a660064
https://doi.org/10.1128/9781555816827
https://doi.org/10.1128/9781555816827