Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Prakash C. Supakar"'
Publikováno v:
Journal of Proteomics & Bioinformatics. :307-314
Cathepsin L is a cysteine protease which degrades connective tissue proteins like collagen, elastin and fibronectin. Increase in the expression of cathepsin L in aged kidney leading to considerable loss of organ function in old age. Recently it has b
Publikováno v:
Molecular and Cellular Probes. 21:355-362
A single step novel multiplex polymerase chain reaction (PCR) has been developed for simultaneous detection of human filarial parasites, Brugia malayi and Wuchereria bancrofti, from blood samples and mosquitoes. The primers used were novel and have b
Publikováno v:
Molecular and Biochemical Parasitology. 155:156-160
The antigenic diversity of Plasmodium falciparum is one of the major obstacles to antimalarial vaccine development. Thus, it becomes obvious to search for a protein that is fairly conserved and is necessary for the parasite to survive in the host cel
Publikováno v:
Molecular and Cellular Biochemistry. 303:239-242
Thyroid hormone (T3) is essential for normal development, differentiation, and metabolic balance of the body. A toxic dose of T(3) in animals increases the basal metabolic rate and reactive oxygen species production, resulting more oxidative stress t
Publikováno v:
Biogerontology. 8:517-525
Besides epigenetic factors, the genetic make-up and differential gene expression not only determines aging and disease susceptibility but also the functional activity of cells in an individual. Analysis of a variety of mammalian tissues revealed that
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 71:285-289
A number of stage-specific antigens have been characterized for vaccine development in Plasmodium falciparum malaria. The polymorphic merozoite surface protein 1 (MSP-1) of Plasmodium falciparum is a major asexual blood stage malaria vaccine candidat
Publikováno v:
Biochemical and Biophysical Research Communications. 309:685-688
Telomerase, a specialized cellular reverse transcriptase, compensates the chromosome shortening during the replication of most eukaryotic cells and contributes to cellular immortalization in cell culture (in vitro) and cancerous cell (in vivo). In th
Autor:
Prakash C. Supakar, Ghazala Zaidi
Publikováno v:
Molecular Biology Reports. 30:121-125
Sequence-specific DNA-protein interactions mediate the regulation of rat androgen receptor (rAR) gene expression. Previously, DNase I footprinting revealed that nuclear factor kappa B (NFkB) binds to region -574 to -554 on rAR promoter and represses
Autor:
Prakash C. Supakar, Ghazala Zaidi
Publikováno v:
Molecular Biology Reports. 29:325-328
Human prostate-specific antigen (PSA) is clinically most useful diagnostic marker for prostate cancer. The PSA gene is partially regulated by androgen hormone via androgen receptor (AR). Several transcription factors including novel transcriptional r
Publikováno v:
Biochemical and Biophysical Research Communications. 272:436-440
Senescence marker protein-30 (SMP30) gene expression declines during aging in mouse liver. SMP30 also plays a role as Ca2+-binding protein localized in cytosol of hepatocytes. To elucidate the molecular mechanism of regulation of SMP30 gene expressio