Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Prajwal Karki"'
Autor:
Sarah Adio, Heena Sharma, Tamara Senyushkina, Prajwal Karki, Cristina Maracci, Ingo Wohlgemuth, Wolf Holtkamp, Frank Peske, Marina V Rodnina
Publikováno v:
eLife, Vol 7 (2018)
Release factors RF1 and RF2 promote hydrolysis of peptidyl-tRNA during translation termination. The GTPase RF3 promotes recycling of RF1 and RF2. Using single molecule FRET and biochemical assays, we show that ribosome termination complexes that carr
Externí odkaz:
https://doaj.org/article/b5b4525df75141a792bec2900ba14734
Autor:
Cristina Maracci, Travis D. Carney, Marina V. Rodnina, Andriy S. Yatsenko, Prajwal Karki, Halyna R. Shcherbata
Publikováno v:
Nucleic Acids Research
SummaryTranslational readthrough (TR) occurs when the ribosome decodes a stop codon as a sense codon, resulting in two protein isoforms synthesized from the same mRNA. TR is pervasive in eukaryotic organisms; however, its biological significance rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5926f1bb704c9798ef08476358fc1c40
https://hdl.handle.net/21.11116/0000-000A-E92A-121.11116/0000-000A-E928-3
https://hdl.handle.net/21.11116/0000-000A-E92A-121.11116/0000-000A-E928-3
Autor:
Tamara Senyushkina, Mariia Klimova, Ingo Wohlgemuth, Bee-Zen Peng, Marina V. Rodnina, Natalia Korniy, Frank Peske, Cristina Maracci, Riccardo Belardinelli, Prajwal Karki, Ekaterina Samatova
Publikováno v:
Nucleic Acids Research
During canonical translation, the ribosome moves along an mRNA from the start to the stop codon in exact steps of one codon at a time. The collinearity of the mRNA and the protein sequence is essential for the quality of the cellular proteome. Sponta
Autor:
Otto Berninghausen, Alexander S. Mankin, Marina V. Rodnina, Roland Beckmann, Cristina Maracci, Nora Vázquez-Laslop, Dorota Klepacki, Daniel N. Wilson, Michael Graf, Prajwal Karki, Tanja Florin
Publikováno v:
Nature Structural & Molecular Biology
Nature structural & molecular biology
Nature structural & molecular biology
Many antibiotics stop bacterial growth by inhibiting different steps of protein synthesis. However, no specific inhibitors of translation termination are known. Proline-rich antimicrobial peptides, a component of the antibacterial defense system of m
Author response: Dynamics of ribosomes and release factors during translation termination in E. coli
Autor:
Prajwal Karki, Ingo Wohlgemuth, Frank Peske, Cristina Maracci, Marina V. Rodnina, Sarah Adio, Wolf Holtkamp, Tamara Senyushkina, Heena Sharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1ce00e4b20c720b06351ba5da5d3832
https://doi.org/10.7554/elife.34252.023
https://doi.org/10.7554/elife.34252.023
Autor:
Wolf Holtkamp, Marina V. Rodnina, Frank Peske, Cristina Maracci, Ingo Wohlgemuth, Sarah Adio, Tamara Senyushkina, Heena Sharma, Prajwal Karki
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Release factors RF1 and RF2 promote hydrolysis of peptidyl-tRNA during translation termination. The GTPase RF3 promotes recycling of RF1 and RF2. Using single molecule FRET and biochemical assays, we show that ribosome termination complexes that carr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0805162b5b84d6cbe76b5d0a8f90cbae
https://doi.org/10.1101/243485
https://doi.org/10.1101/243485
Publikováno v:
International Journal of Research in Medical Sciences. 6:1101
Background: The relationship between autonomic system and cardiovascular mortality is significant and this study can be used to study the hereditary risk that an individual carries to develop any autonomic dysfunction and its effect on cardiovascular