Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Prajwal BODDU"'
Autor:
Anne Olazabal-Herrero, Boxue He, Youngho Kwon, Abhishek K. Gupta, Arijit Dutta, Yuxin Huang, Prajwal Boddu, Zhuobin Liang, Fengshan Liang, Yaqun Teng, Li Lan, Xiaoyong Chen, Huadong Pei, Manoj M. Pillai, Patrick Sung, Gary M. Kupfer
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113610- (2024)
Summary: Fanconi anemia (FA) is characterized by congenital abnormalities, bone marrow failure, and cancer susceptibility. The central FA protein complex FANCI/FANCD2 (ID2) is activated by monoubiquitination and recruits DNA repair proteins for inter
Externí odkaz:
https://doaj.org/article/bc92b447e5014f469f04a528e03fd245
Autor:
Sang T. Kim, Ajay Sheshadri, Vickie Shannon, Dimitrios P. Kontoyiannis, Hagop Kantarjian, Guillermo Garcia-Manero, Farhad Ravandi, Jin S. Im, Prajwal Boddu, Lara Bashoura, Diwakar D. Balachandran, Scott E. Evans, Saadia Faiz, Wilfredo Ruiz Vazquez, Margarita Divenko, Rohit Mathur, Samantha P. Tippen, Curtis Gumbs, Sattva S. Neelapu, Aung Naing, Linghua Wang, Adi Diab, Andrew Futreal, Roza Nurieva, Naval Daver
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) treated with immune checkpoint inhibitors (ICIs) are at risk of pneumonitis as well as pneumonia (combined henceforth as ICI-related pulmonary complications). Little is kno
Externí odkaz:
https://doaj.org/article/dc5a725f54754ba59720d7c06fbd8deb
Autor:
Prajwal Boddu, Hagop Kantarjian, Gautam Borthakur, Tapan Kadia, Naval Daver, Sherry Pierce, Michael Andreeff, Farhad Ravandi, Jorge Cortes, Steven M. Kornblau
Publikováno v:
Blood Advances, Vol 1, Iss 19, Pp 1546-1550 (2017)
Abstract: Although FLT3 internal tandem duplication (ITD) mutations in acute myeloid leukemia (AML) confer an adverse prognosis, co-occurrence with a nucleophosphomin (NPM1) mutation partially improves response and survival outcomes. In contrast, sim
Externí odkaz:
https://doaj.org/article/8cab84722f7749258739ed0bc0637a41
Autor:
Prajwal Boddu, Hagop M. Kantarjian, Guillermo Garcia-Manero, Farhad Ravandi, Srdan Verstovsek, Elias Jabbour, Gautam Borthakur, Marina Konopleva, Kapil N. Bhalla, Naval Daver, Courtney D. DiNardo, Christopher B. Benton, Koichi Takahashi, Zeev Estrov, Sherry R. Pierce, Michael Andreeff, Jorge E. Cortes, Tapan M. Kadia
Publikováno v:
Blood Advances, Vol 1, Iss 17, Pp 1312-1323 (2017)
Abstract: Secondary acute myeloid leukemia (s-AML) includes therapy-related AML and AML evolving from antecedent hematological disorder (AHD). s-AML arising after treating AHD likely represents a prognostically distinct, high-risk disease category. I
Externí odkaz:
https://doaj.org/article/fb67d5abf34d43608bfe5e998d063e71
Publikováno v:
Journal of Clinical and Translational Science, Vol 5, Pp 22-22 (2021)
ABSTRACT IMPACT: We describe a novel methodology that combines CRISPR/Cas9-induced double stranded DNA breaks with homology dependent repair from an adeno associated virus (AAV) encoded template to generate single-allele edited isogenic cell line mod
Externí odkaz:
https://doaj.org/article/95372f23593e41f5b1522aa86ef7962b
Publikováno v:
Chinese Journal of Lung Cancer, Vol 19, Iss 11, Pp 725-730 (2016)
Background and Objectives: Search for inexpensive laboratory markers have identified associations between blood counts and lung cancer outcomes. In this study, we evaluated the prognostic value of paraneoplastic leukocytosis (p-Leukocytosis) and para
Externí odkaz:
https://doaj.org/article/ce0ca026496b440da970087c0eb8e6c0
Publikováno v:
Case Reports in Dermatology, Vol 8, Iss 3, Pp 278-282 (2016)
Vesiculobullous eruptions in the elderly represent a diverse range of varying pathophysiologies and can present a significant clinical dilemma to the diagnostician. Diagnosis requires a careful review of clinical history, attention to detail on physi
Externí odkaz:
https://doaj.org/article/42bc5a16527741b488237b7102002b95
Autor:
Prajwal Boddu, Gautam Borthakur, Mythili Koneru, Xuelin Huang, Kiran Naqvi, William Wierda, Prithviraj Bose, Elias Jabbour, Zeev Estrov, Jan Burger, Yesid Alvarado, April Deshmukh, Ami Patel, Antonio Cavazos, Lina Han, Jorge E. Cortes, Hagop Kantarjian, Michael Andreeff, Marina Konopleva
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Background: The CXCR4/SDF-1α axis plays a vital role in the retention of stem cells within the bone marrow and downstream activation of cell survival signaling pathways. LY2510924, a second generation CXCR4, showed significant anti-leukemia activity
Externí odkaz:
https://doaj.org/article/c2ad7be1c5364b8ebd00f91dd7c3247a
Publikováno v:
Journal of Community Hospital Internal Medicine Perspectives, Vol 6, Iss 4, Pp 1-3 (2016)
Healthcare providers use antinuclear antibodies (ANAs) to screen and diagnose patients with autoimmune diseases. In the recent years, commercial multiplex ANA kits have emerged as a convenient and fast diagnostic method. Diagnostic testing should fol
Externí odkaz:
https://doaj.org/article/5092285974974d8886e17146f9223e51
Publikováno v:
Cardiology Research and Practice, Vol 2017 (2017)
Thyroid hormones play an important role in regulating different metabolism functions and multiple organs’ performance. Changes in the thyroid hormone axis can lead to profound effects on the stability of vital organs and systems, especially the car
Externí odkaz:
https://doaj.org/article/8404918e294f4a5ea8a01161f7293440