Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Prajwal A. Deshmukh"'
Publikováno v:
Blockchain for Smart Systems ISBN: 9781003203933
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0143dfdff9f4520f358c463073ba3135
https://doi.org/10.1201/9781003203933-12
https://doi.org/10.1201/9781003203933-12
Autor:
Sripad R. Bellary, Prajwal A. Deshmukh, Minoti Magotra, Frank T. Schwender, Yao Sun, German Kamalov, Amy L. de Jongh Curry, Karl T. Weber
Publikováno v:
Journal of Cardiovascular Pharmacology. 58:487-491
Myocardial fibrosis is considered a substrate for fatal ventricular arrhythmias (VAs). In rats receiving aldosterone/salt treatment (ALDOST) for ≥4 weeks, foci of myocardial scarring that replace necrotic cardiomyocytes appear scattered throughout
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 292:H792-H799
The present study demonstrates that acute activation with either β-adrenergic receptor agonists or H2O2treatment increases protein phosphatase 2a (PP2a) activity in ventricular myocytes. PP2a activation occurs concomitant with an increase in methyla
Autor:
German, Kamalov, Prajwal A, Deshmukh, Narina Y, Baburyan, Malay S, Gandhi, Patti L, Johnson, Robert A, Ahokas, Syamal K, Bhattacharya, Yao, Sun, Ivan C, Gerling, Karl T, Weber
Publikováno v:
Journal of cardiovascular pharmacology. 53(5)
A dyshomeostasis of extra- and intracellular Ca(2+) and Zn(2+) occurs in rats receiving chronic aldosterone/salt treatment (ALDOST). Herein, we hypothesized that the dyshomeostasis of intracellular Ca(2+) and Zn(2+) is intrinsically coupled that alte
Autor:
Karl T. Weber, Yao Sun, Jonathan T Whaley, Tieqiang Zhao, Jill R Tichy, Malay S. Gandhi, Syamal K. Bhattacharya, Robert A. Ahokas, Prajwal A. Deshmukh, German Kamalov, Wenyuan Zhao, Ivan C. Gerling
Publikováno v:
Journal of cardiovascular pharmacology. 52(3)
Iterations in Ca2+ and Mg2+ balance accompany aldosteronism (inappropriate for dietary Na+ intake). Increased Zn excretion and Zn translocation to injured tissues, including the heart, also occurs. Several causes and consequences of Zn dyshomeostasis
Publikováno v:
Journal of Investigative Medicine. 55:S255-S256
Purpose In addition to the excessive accumulation of intracellular Ca2+ that appears in the myocardium with chronic aldosteronism, there is a rise in Zn and an increased expression of metallothionein (MT)-1, a Zn-binding protein, in cardiac tissue. U
Autor:
Robert A. Ahokas, Karl T. Weber, German Kamalov, Prajwal A. Deshmukh, Yao Sun, Syamal K. Bhattacharya
Publikováno v:
Journal of Investigative Medicine. 55:S280
Purpose Aldosterone/salt treatment (ALDOST) is associated with increased urinary losses of Ca2+ and Zn, which can be prevented by spironolactone (S), an aldosterone receptor antagonist. The hypercalciuria and hyperzincuria of aldosteronism lead to hy
Autor:
Prajwal A. Deshmukh, Robert A. Ahokas, Syamal K. Bhattacharya, German Kamalov, Yao Sun, Karl T. Weber
Publikováno v:
Journal of Investigative Medicine. 55:S255
Purpose An excessive accumulation of intracellular Ca2+ occurs in diverse tissues, including the heart, in rats with aldosterone/salt treatment. This Ca2+ overloading includes total intracellular Ca2+ (both organellar and cytosolic compartments) as w