Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Prajwal, Ciryam"'
Autor:
Matthew R. Woodward, DO, Chris L. Wells, PhD, Shannon Arnold, BA, Farra Dorman, PT, Zaka Ahmed, MBBS, Nicholas A. Morris, MD, Prajwal Ciryam, MD, PhD, Jamie E. Podell, MD, Wan-Tsu W. Chang, MD, W. Denney Zimmerman, DO, Melissa Motta, MD, Bilal Butt, MD, Melissa B. Pergakis, MD, Mohamed Labib, MD, Ting I. Wang, MA, Brian L. Edlow, MD, Neeraj Badjatia, MD, Robynne Braun, MD, PhD, Gunjan Y. Parikh, MD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1101 (2024)
OBJECTIVES:. Accurate classification of disorders of consciousness (DoC) is key in developing rehabilitation plans after brain injury. The Coma Recovery Scale—Revised (CRS-R) is a sensitive measure of consciousness validated in the rehabilitation p
Externí odkaz:
https://doaj.org/article/7c5c673a96624eaf8f9851329fd30bd1
Autor:
Matthew R. Woodward, Adam Kardon, Jody Manners, Samantha Schleicher, Melissa B. Pergakis, Prajwal Ciryam, Jamie Podell, William Denney Zimmerman, Samuel M. Galvagno, Jr, Bilal Butt, Jennifer Pritchard, Gunjan Y. Parikh, Emily J. Gilmore, Neeraj Badjatia, Nicholas A. Morris
Publikováno v:
Epilepsy & Behavior Reports, Vol 25, Iss , Pp 100645- (2024)
Endotracheal intubation, frequently required during management of refractory status epilepticus (RSE), can be facilitated by anesthetic medications; however, their effectiveness for RSE control is unknown. We performed a single-center retrospective r
Externí odkaz:
https://doaj.org/article/eef3613602824e268b4fecb934fc491a
Autor:
J. Marc Simard, Bradley Wilhelmy, Natalya Tsymbalyuk, Bosung Shim, Jesse A. Stokum, Madison Evans, Anandita Gaur, Cigdem Tosun, Kaspar Keledjian, Prajwal Ciryam, Riccardo Serra, Volodymyr Gerzanich
Publikováno v:
Brain Sciences, Vol 14, Iss 3, p 229 (2024)
In human stroke, brain swelling is an important predictor of neurological outcome and mortality, yet treatments to reduce or prevent brain swelling are extremely limited, due in part to an inadequate understanding of mechanisms. In preclinical studie
Externí odkaz:
https://doaj.org/article/c88f3a70ab504422be2af4e18e61d667
Autor:
Prajwal Ciryam, Matthew Antalek, Fernando Cid, Gian Gaetano Tartaglia, Christopher M. Dobson, Anne-Katrin Guettsches, Britta Eggers, Matthias Vorgerd, Katrin Marcus, Rudolf A. Kley, Richard I. Morimoto, Michele Vendruscolo, Conrad C. Weihl
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Protein aggregation is a pathological feature of neurodegenerative disorders. We previously demonstrated that protein inclusions in the brain are composed of supersaturated proteins, which are abundant and aggregation-prone, and form a metas
Externí odkaz:
https://doaj.org/article/98b5bb1d9beb43de9d33f052fb29e0d6
Autor:
Rosie Freer, Pietro Sormanni, Prajwal Ciryam, Burkhard Rammner, Silvio O. Rizzoli, Christopher M. Dobson, Michele Vendruscolo
Publikováno v:
Heliyon, Vol 5, Iss 11, Pp e02589- (2019)
Neurodegenerative disorders progress across the brain in characteristic spatio-temporal patterns. A better understanding of the factors underlying the specific cell and tissue vulnerability responsible for such patterns could help identify the molecu
Externí odkaz:
https://doaj.org/article/90e3ad7beb724453b20ee600c5d5be71
Autor:
Ajeet K Sharma, Pietro Sormanni, Nabeel Ahmed, Prajwal Ciryam, Ulrike A Friedrich, Günter Kramer, Edward P O'Brien
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 5, p e1007070 (2019)
Analysis methods based on simulations and optimization have been previously developed to estimate relative translation rates from next-generation sequencing data. Translation involves molecules and chemical reactions, hence bioinformatics methods con
Externí odkaz:
https://doaj.org/article/0de2347b544d46a793ed36407ad3ef9f
Autor:
Sara Radmard, Savina Reid, Prajwal Ciryam, Alexandra Boubour, Nhan Ho, Jason Zucker, Dean Sayre, William G. Greendyke, Benjamin A. Miko, Marcus R. Pereira, Susan Whittier, Daniel A. Green, Kiran T. Thakur
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Objective: To assess the clinical utilization and performance of the FilmArray® Meningitis/Encephalitis (ME) multiplex polymerase chain reaction (PCR) panel in a hospital setting.Background: Rapid diagnosis and treatment of central nervous system (C
Externí odkaz:
https://doaj.org/article/61e91eed137f4a4eac5cdf96899710fe
Publikováno v:
Journal of Neurotrauma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67e227ab415c03863fbffc1e30cd51ba
https://doi.org/10.1089/neu.2023.0135
https://doi.org/10.1089/neu.2023.0135
Autor:
Prajwal Ciryam, Gian Gaetano Tartaglia, Richard I. Morimoto, Christopher M. Dobson, Michele Vendruscolo
Publikováno v:
Cell Reports, Vol 5, Iss 3, Pp 781-790 (2013)
The maintenance of protein solubility is a fundamental aspect of cellular homeostasis because protein aggregation is associated with a wide variety of human diseases. Numerous proteins unrelated in sequence and structure, however, can misfold and agg
Externí odkaz:
https://doaj.org/article/f636dedaca1440e389ed7abd3e2d1aac
Autor:
Christopher M. Dobson, Michele Vendruscolo, Ian P. Blair, Justin J. Yerbury, Lezanne Ooi, Prajwal Ciryam
Publikováno v:
Neuroscience Letters. 704:89-94
Amyotrophic lateral sclerosis (ALS) is a heterogeneous motor neuron disease with familial forms linked to numerous mutations in a range of genes. The resulting variant proteins, including SOD1, TDP-43, and FUS, disturb protein homeostasis in a variet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1b012e6e499c6cdad5a48f9367eff3
https://doi.org/10.1016/j.neulet.2019.04.001
https://doi.org/10.1016/j.neulet.2019.04.001