Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Prajna Behera"'
Autor:
Christophe Quéva, Lorena Lerner, Edward M. Kennedy, Sonia Feau, Melissa W. Hayes, Mitchel H. Finer, Allison Colthart, Michael Ball, Caitlin Goshert, Judith Jacques, Prajna Behera, Lingxin Kong, Daniel Wambua, Jacqueline Hewett, Terry Farkaly, Jennifer S. Lee, Peter Grzesik, Agnieszka Denslow, Brian B. Haines
ONCR-177 is an engineered recombinant oncolytic herpes simplex virus (HSV) with complementary safety mechanisms, including tissue-specific miRNA attenuation and mutant UL37 to inhibit replication, neuropathic activity, and latency in normal cells. ON
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a6663d25128f50d686dbfb13f50074
https://doi.org/10.1158/2326-6066.c.6550257.v1
https://doi.org/10.1158/2326-6066.c.6550257.v1
Autor:
Christophe Quéva, Lorena Lerner, Edward M. Kennedy, Sonia Feau, Melissa W. Hayes, Mitchel H. Finer, Allison Colthart, Michael Ball, Caitlin Goshert, Judith Jacques, Prajna Behera, Lingxin Kong, Daniel Wambua, Jacqueline Hewett, Terry Farkaly, Jennifer S. Lee, Peter Grzesik, Agnieszka Denslow, Brian B. Haines
Supplemental Tables and Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfb51c9f36daf3b0ec0c09daa990df8
https://doi.org/10.1158/2326-6066.22543431.v1
https://doi.org/10.1158/2326-6066.22543431.v1
Autor:
Mariano S. Viapiano, E. Antonio Chiocca, Diego J. Rodriguez-Gil, Sadhak Sengupta, Lina M. Barrera-Arenas, Sharon L. Longo, Vivek Bhaskaran, Prajna Behera, Mohan S. Nandhu
Legends of Figs S1 to S8, unmarked version
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636cb8e181fc57e3866f26484b09934c
https://doi.org/10.1158/1078-0432.22464189.v1
https://doi.org/10.1158/1078-0432.22464189.v1
Autor:
Mariano S. Viapiano, E. Antonio Chiocca, Diego J. Rodriguez-Gil, Sadhak Sengupta, Lina M. Barrera-Arenas, Sharon L. Longo, Vivek Bhaskaran, Prajna Behera, Mohan S. Nandhu
Supplemental Table I: Antibodies used for Western blotting and immunohistochemistry (IHC); Supplemental Table II: Sequences used for qRT-PCR primers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a23b02d6931e76da93c5aa263b9fda
https://doi.org/10.1158/1078-0432.22464186
https://doi.org/10.1158/1078-0432.22464186
Autor:
Mariano S. Viapiano, E. Antonio Chiocca, Diego J. Rodriguez-Gil, Sadhak Sengupta, Lina M. Barrera-Arenas, Sharon L. Longo, Vivek Bhaskaran, Prajna Behera, Mohan S. Nandhu
Figure S1: Generation of mAb428.2 antibody; Figure S2: Affinity of mAb428.2 for fibulin-3; Figure S3: mAb428.2 binds to cell-surface and interstitial fibulin-3; Figure S4: mAb428.2 does not cause acute toxicity; Figure S5: Locally-delivered mAb428.2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48dc2f9a3e5578f8da0db8a9ecc24189
https://doi.org/10.1158/1078-0432.22464192
https://doi.org/10.1158/1078-0432.22464192
Autor:
Michał Nowicki, Hong Zhang, Franz Ricklefs, Michael Gutknecht, Charles Cobbs, Arun K. Rooj, Prajna Behera, Carmela Passaro, Hirotaka Ito, Sean E. Lawler, Rachel Zane, Lai Ding, Marion Griessl, E. Antonio Chiocca, C. David James, Mykola Zdioruk, Magdalena Skubal, Harald Krenzlin, Sharon Peled, Charles H. Cook, Korneel Grauwet, Viola Lorenz
Publikováno v:
Journal of Clinical Investigation. 129:1671-1683
Cytomegalovirus (CMV) has been implicated in glioblastoma (GBM); however, a mechanistic connection in vivo has not been established. The purpose of this study is to characterize the effects of murine CMV (MCMV) on GBM growth in murine models. Syngene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f6ea3cfe25aef288b9f957769e051e
https://doi.org/10.1172/jci123375
https://doi.org/10.1172/jci123375
Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma
Autor:
Lina M Barrera-Arenas, Sadhak Sengupta, Vivek Bhaskaran, Diego J. Rodriguez-Gil, Mohan Sobhana Nandhu, Mariano S. Viapiano, Sharon L. Longo, E. Antonio Chiocca, Prajna Behera
Publikováno v:
Clinical Cancer Research. 24:821-833
Purpose: We sought a novel approach against glioblastomas (GBM) focused on targeting signaling molecules localized in the tumor extracellular matrix (ECM). We investigated fibulin-3, a glycoprotein that forms the ECM scaffold of GBMs and promotes tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0d2b2b1e84d74c9b3973713a69ce41
https://doi.org/10.1158/1078-0432.ccr-17-1628
https://doi.org/10.1158/1078-0432.ccr-17-1628
Autor:
Jennifer S. Lee, Agnieszka Denslow, Brian B. Haines, Christophe Quéva, Michael Ball, Lorenz Ponce, Caroline Webb, Jacqueline Gursha, Daniel Wambua, Cecilia Kwong, Finer Mitchell H, Michael Paglia, Prajna Behera, Judith Jacques, Lorena Lerner, Allison Colthart, Lingxin Kong, Peter Grzesik, Terry Farkaly, Laura Viggiano Salta, Edward M. Kennedy, Caity Montagna
Publikováno v:
Cancer Immunology Research. 8:B23-B23
Although oncolytic viruses have shown clinical efficacy for local treatment of cancerous tumors, the ability to induce immune-mediated regression to visceral lesions is not robust. Immune checkpoint modulation has been efficacious in a fraction of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9b45fcb32c487c6e1a16aaa7a774ea4
https://doi.org/10.1158/2326-6074.tumimm18-b23
https://doi.org/10.1158/2326-6074.tumimm18-b23
Autor:
Christophe Quéva, Jacob Spinale, Lingxin Kong, Prajna Behera, Jennifer S. Lee, Terry Farkaly, Lorena Lerner, Agnieska Denslow, Sonia Feau, Melissa Hayes, Jacqueline Gurshaw, Peter Grzesik, Edward M. Kennedy, Brian B. Haines, Daniel Wambua, Shreeya Khatiwada
Publikováno v:
Cancer Immunology Research. 8:B74-B74
Oncolytic viruses represent a new class of therapeutic agents for the treatment of cancers that poorly respond to immune checkpoint inhibitors. Oncorus is developing ONCR-177, an oncolytic herpes simplex virus engineered for enhanced oncolysis and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f504b7e20edbc8fc77c0e69776fb5c22
https://doi.org/10.1158/2326-6074.tumimm19-b74
https://doi.org/10.1158/2326-6074.tumimm19-b74
Publikováno v:
Sensors and Actuators B: Chemical. 192:697-707
Real-time, continuous monitoring of local oxygen contents at the cellular level is desirable both for the study of cancer cell biology and in tissue engineering. In this paper, we report the successful fabrication of polydimethylsiloxane (PDMS) nanof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a7b6ca6dc0c9ae3ec7ffaf74bd1e77
https://doi.org/10.1016/j.snb.2013.10.084
https://doi.org/10.1016/j.snb.2013.10.084