Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Prajeeda M. Nair"'
Autor:
Wayne T. Muraoka, Prajeeda M. Nair, Daniel N. Darlington, Xiaowu Wu, James A. Bynum, Andrew P. Cap
Publikováno v:
Platelets, Vol 34, Iss 1 (2023)
Blood platelets are crucial to prevent excessive bleeding following injury to blood vessels. Platelets are crucial for the formation of clots and for clot strength. Platelet activation involves aggregation, attachment to fibrin and clot retraction. M
Externí odkaz:
https://doaj.org/article/ba0933e5b21a4792bd6414b63fc9d49c
Autor:
James A. Bynum, Prajeeda M Nair, Adrienne R. Wells, Xiaowu Wu, Michael A. Meledeo, Aswathi Cheeniyil, Andrew P. Cap, Anand K. Ramasubramanian, Bin Liu, John W. Weisel, Kai P. Leung
Publikováno v:
Transfusion. 61
Although it is well established that transfusion of platelets in cases of severe bleeding reduces mortality, the availability of platelets is hampered by harsh restrictions on shelf life due to elevated risks of microbial contamination and functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c9c98eae268a2f76d276c9f73a3901
https://doi.org/10.1111/trf.16530
https://doi.org/10.1111/trf.16530
Autor:
Jason K. Burris, Andrew P. Cap, Prajeeda M Nair, Kristin M Reddoch-Cardenas, Michael A. Meledeo, Matthew Rendo
Publikováno v:
Seminars in Hematology
Hematologic diseases include a broad range of acquired and congenital disorders, many of which affect plasma proteins that control hemostasis and immune responses. Therapeutic interventions for these disorders include transfusion of plasma, cryopreci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a55bfc6dadc20af509aa5aeac6790a
https://pubmed.ncbi.nlm.nih.gov/32892846
https://pubmed.ncbi.nlm.nih.gov/32892846
Autor:
Charles S. Cox, Prajeeda M Nair, Andrew P. Cap, Brijesh S. Gill, Charles E. Wade, James A. Bynum, Mitchell J. George
Publikováno v:
Platelets. 29:431-439
The purpose of this review is to explore the relationship between platelet bioenergetics and biomechanics and how this relationship affects the clinical interpretation of platelet function devices. Recent experimental and technological advances highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b489421cc7e79ad4cbf6f54193712c96
https://doi.org/10.1080/09537104.2018.1453062
https://doi.org/10.1080/09537104.2018.1453062
Autor:
Grant C. Peltier, Prajeeda M Nair, Andrew P. Cap, Michael A. Meledeo, Tiffani C. Chance, Anand K. Ramasubramanian, Kristin M Reddoch-Cardenas, James A. Bynum
Publikováno v:
TransfusionREFERENCES. 61(1)
Background Cold storage of platelets in plasma maintains hemostatic function and is an attractive alternative to room temperature platelets (RTPs). We have recently shown that functional differences between cold-stored platelets (CSPs) and RTPs after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3cc884105ecfe9c9a6fe9b86e93376
https://pubmed.ncbi.nlm.nih.gov/33294977
https://pubmed.ncbi.nlm.nih.gov/33294977
Autor:
Harjot S Grewal, Dustin M Nguyen, Sang Joon John Lee, Prajeeda M Nair, Amit K. Saha, Chaitanya Puligundla, Anand K. Ramasubramanian, Andrew P. Cap
Publikováno v:
Biomechanics and modeling in mechanobiology. 19(1)
Optimal strength and stability of blood clots are keys to hemostasis and in prevention of hemorrhagic or thrombotic complications. Clots are biocomposite materials composed of fibrin network enmeshing platelets and other blood cells. We have previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68536a54bf0621ce41de7c565fa028e2
https://pubmed.ncbi.nlm.nih.gov/31312933
https://pubmed.ncbi.nlm.nih.gov/31312933
Autor:
Kristin M Reddoch-Cardenas, Andrew P. Cap, Xiaowu Wu, Michael A. Meledeo, Anand K. Ramasubramanian, Daniel N. Darlington, Prajeeda M Nair, James A. Bynum
Publikováno v:
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. 58(1)
Early administration of blood products following severe trauma is pivotal for establishing hemostasis and achieving successful outcomes. Platelet transfusions, in particular, provide rapid control of hemostasis and help to restore platelet dysfunctio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de4872f78e570d3e979c690f434d1f6
https://pubmed.ncbi.nlm.nih.gov/30704925
https://pubmed.ncbi.nlm.nih.gov/30704925
Autor:
Prajeeda M Nair, Heather F. Pidcoke, Andrew P. Cap, Robbie K. Montgomery, Kristin M. Reddoch, Shatha F. Dallo, Anand K. Ramasubramanian, Shaunak G. Pandya
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Currently, platelets (PLTs) stored at room temperature (RT) for 5-7 days with gentle agitation are exclusively used for transfusion although FDA recently clarified that apheresis PLTs stored at 4°C for up to 72 hours may be used for treating active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29dc31ae579084408f641da679d1fec7
https://doi.org/10.1161/atvb.37.suppl_1.147
https://doi.org/10.1161/atvb.37.suppl_1.147
Autor:
Grantham C. Peltier, Michael A. Meledeo, Prajeeda M Nair, James A. Bynum, Kristin M Reddoch-Cardenas, Xiaowu Wu, Bin Liu, Andrew P. Cap
Publikováno v:
Blood. 134:2450-2450
Background: Platelet (PLT) hemostatic responses are heavily dependent on PLT bioenergetics which drives the generation of PLT contractile forces and contribute to mechanical hemostasis. Although effective clot retraction (CR) requires PLT adhesion, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b06f49b9896c5c3a38092b45c792d6ec
https://doi.org/10.1182/blood-2019-131116
https://doi.org/10.1182/blood-2019-131116
Autor:
Kristin M. Reddoch, Shatha F. Dallo, Shaunak G. Pandya, Andrew P. Cap, Robbie K. Montgomery, Anand K. Ramasubramanian, Prajeeda M Nair, Heather F. Pidcoke
Publikováno v:
British journal of haematology. 178(1)
Summary Currently, platelets for transfusion are stored at room temperature (RT) for 5–7 days with gentle agitation, but this is less than optimal because of loss of function and risk of bacterial contamination. We have previously demonstrated that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb808f8b65db2dac4f06ad861b93c48
https://pubmed.ncbi.nlm.nih.gov/28612370
https://pubmed.ncbi.nlm.nih.gov/28612370