Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Prajakta Warang"'
Autor:
Alexandra Sakai, Gagandeep Singh, Mahsa Khoshbakht, Scott Bittner, Christiane V. Löhr, Randy Diaz-Tapia, Prajakta Warang, Kris White, Luke Le Luo, Blanton Tolbert, Mario Blanco, Amy Chow, Mitchell Guttman, Cuiping Li, Yiming Bao, Joses Ho, Sebastian Maurer-Stroh, Arnab Chatterjee, Sumit Chanda, Adolfo García-Sastre, Michael Schotsaert, John R. Teijaro, Hong M. Moulton, David A. Stein
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102331- (2024)
Further development of direct-acting antiviral agents against human SARS-CoV-2 infections remains a public health priority. Here, we report that an antisense peptide-conjugated morpholino oligomer (PPMO) named 5′END-2, targeting a highly conserved
Externí odkaz:
https://doaj.org/article/cde8602c5de243599a35a2d086e74e3b
Autor:
Stefan Slamanig, Irene González-Domínguez, Lauren A. Chang, Nicholas Lemus, Tsoi Ying Lai, Jose Luis Martínez, Gagandeep Singh, Victoria Dolange, Adam Abdeljawad, Shreyas Kowdle, Moataz Noureddine, Prajakta Warang, Benhur Lee, Adolfo García-Sastre, Florian Krammer, Michael Schotsaert, Peter Palese, Weina Sun
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105185- (2024)
Summary: Background: In order to prevent the emergence and spread of future variants of concern of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), developing vaccines capable of stopping transmission is crucial. The SARS-CoV-2 vaccine N
Externí odkaz:
https://doaj.org/article/18bda2ebe71446cb81d8e9be9b791fab
Autor:
Sonia Jangra, Jeffrey J. Landers, Gabriel Laghlali, Raveen Rathnasinghe, Prajakta Warang, Seok-Chan Park, Jessica. J. O’Konek, Gagandeep Singh, Katarzyna W. Janczak, Adolfo García-Sastre, Nandini Arya, Dilara Karadag, James R. Baker, Michael Schotsaert, Pamela T. Wong
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Multiple FDA-approved SARS-CoV-2 vaccines currently provide excellent protection against severe disease. Despite this, immunity can wane relatively fast, particularly in the elderly and novel viral variants capable of evading infection- and
Externí odkaz:
https://doaj.org/article/e0f2e171cb6d49a6bff9be7e335d5f23
Autor:
Miguel Á. Muñoz-Alía, Rebecca A. Nace, Baskar Balakrishnan, Lianwen Zhang, Nandakumar Packiriswamy, Gagandeep Singh, Prajakta Warang, Ignacio Mena, Riya Narjari, Rianna Vandergaast, Kah-Whye Peng, Adolfo García-Sastre, Michael Schotsaert, Stephen J. Russell
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Serum titers of SARS-CoV-2-neutralizing antibodies (nAbs) correlate well with protection from symptomatic COVID-19 but decay rapidly in the months following vaccination or infection. In contrast, measles-protective nAb titers are lifelong af
Externí odkaz:
https://doaj.org/article/cd8acd208724481bb4522d65973e788c
Autor:
Juan García-Bernalt Diego, Gagandeep Singh, Sonia Jangra, Kim Handrejk, Manon Laporte, Lauren A Chang, Sara S El Zahed, Lars Pache, Max W Chang, Prajakta Warang, Sadaf Aslam, Ignacio Mena, Brett T Webb, Christopher Benner, Adolfo García-Sastre, Michael Schotsaert
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011805 (2024)
Hybrid immunity (vaccination + natural infection) to SARS-CoV-2 provides superior protection to re-infection. We performed immune profiling studies during breakthrough infections in mRNA-vaccinated hamsters to evaluate hybrid immunity induction. The
Externí odkaz:
https://doaj.org/article/b8157faea3be4694babe8d2522d568aa
Autor:
Lauren A. Chang, Angela Choi, Raveen Rathnasinghe, Prajakta Warang, Moataz Noureddine, Sonia Jangra, Yong Chen, Bruno G. De Geest, Michael Schotsaert
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Eosinophils are important mediators of mucosal tissue homeostasis, anti-helminth responses, and allergy. Lung eosinophilia has previously been linked to aberrant Type 2-skewed T cell responses to respiratory viral infection and may also be a conseque
Externí odkaz:
https://doaj.org/article/f7543b749d5d433c9261b41937fc7018
Autor:
Miguel Á. Muñoz-Alía, Rebecca A. Nace, Baskar Balakrishnan, Lianwen Zhang, Nandakumar Packiriswamy, Gagandeep Singh, Prajakta Warang, Ignacio Mena, Riya Narjari, Rianna Vandergaast, Adolfo García-Sastre, Michael Schotsaert, Stephen J. Russell
Publikováno v:
bioRxiv
Serum titers of SARS-CoV-2 neutralizing antibodies (nAb) correlate well with protection from symptomatic COVID-19, but decay rapidly in the months following vaccination or infection. In contrast, measles-protective nAb titers are life-long after meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e9d892f0a6253ee8d6f4abb86a64f3
https://europepmc.org/articles/PMC9774211/
https://europepmc.org/articles/PMC9774211/
Autor:
J. Andrew Duty, Thomas Kraus, Heyue Zhou, Yanliang Zhang, Namir Shaabani, Soner Yildiz, Na Du, Alok Singh, Lisa Miorin, Donghui Li, Karen Stegman, Sabrina Ophir, Xia Cao, Kristina Atanasoff, Reyna Lim, Ignacio Mena, Nicole M. Bouvier, Shreyas Kowdle, Juan Manuel Carreño, Laura Rivero-Nava, Ariel Raskin, Elena Moreno, Sachi Johnson, Raveen Rathnasinghe, Chin I. Pai, Thomas Kehrer, Elizabeth Paz Cabral, Sonia Jangra, Laura Healy, Gagandeep Singh, Prajakta Warang, Viviana Simon, Emilia Mia Sordillo, Harm van Bakel, Yonghong Liu, Weina Sun, Lisa Kerwin, John Teijaro, Michael Schotsaert, Florian Krammer, Damien Bresson, Adolfo García-Sastre, Yanwen Fu, Benhur Lee, Colin Powers, Thomas Moran, Henry Ji, Domenico Tortorella, Robert Allen
Publikováno v:
Med (New York, N.Y.). 3(10)
The continual emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern, in particular the newly emerged Omicron (B.1.1.529) variant and its BA.X lineages, has rendered ineffective a number of previously FDA emerge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9023a9ea9333e0aac6a98e5e560ddfa8
https://pubmed.ncbi.nlm.nih.gov/36044897
https://pubmed.ncbi.nlm.nih.gov/36044897
Autor:
J. Andrew Duty, Thomas Kraus, Heyue Zhou, Yanliang Zhang, Namir Shaabani, Soner Yildiz, Na Du, Alok Singh, Lisa Miorin, Donghui Li, Karen Stegman, Sabrina Ophir, Xia Cao, Kristina Atanasoff, Reyna Lim, Shreyas Kowdle, Juan Manuel Carreño, Laura Rivero-Nava, Ariel Raskin, Elena Moreno, Sachi Johnson, Raveen Rathnasinghe, Chin I Pai, Thomas Kehrer, Elizabeth Paz Cabral, Sonia Jangra, Laura Healy, Gagandeep Singh, Prajakta Warang, Viviana Simon, Mia Emilia Sordillo, Harm van Bakel, Yonghong Liu, Weina Sun, Lisa Kerwin, Peter Palese, John Teijaro, Michael Schotsaert, Florian Krammer, Damien Bresson, Adolfo García-Sastre, Yanwen Fu, Benhur Lee, Colin Powers, Thomas Moran, Henry Ji, Domenico Tortorella, Robert Allen
The continual emergence of SARS-CoV-2 variants of concern, in particular the newly emerged Omicron (B.1.1.529) variant, has rendered ineffective a number of previously EUA approved SARS-CoV-2 neutralizing antibody therapies. Furthermore, even those a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afdbf0b1baf428680010d00a276bb180
https://doi.org/10.1101/2022.01.19.476998
https://doi.org/10.1101/2022.01.19.476998
Autor:
Michael Diamond, Peter Halfmann, Tadashi Maemura, Kiyoko Iwatsuki-Horimoto, Shun Iida, Maki Kiso, Suzanne Scheaffer, Tamarand Darling, Astha Joshi, Samantha Loeber, Stephanie Foster, Baoling Ying, Bradley Whitener, Katharine Floyd, Michiko Ujie, Noriko Nakajima, Mutsumi Ito, Ryan Wright, Ryuta Uraki, Rong Li, Yuko Sakai, Yanan Liu, Deanna Larson, Jorge Osorio, Juan Hernandez-Ortiz, Karl Čiuoderis, Kelsey Florek, Mit Patel, Allen Bateman, Abby Odle, Lok-Yin Wong, Zhongde Wang, Venkata Viswanadh Edara, Zhenlu Chong, Larissa Thackray, Hiroshi Ueki, Seiya Yamayoshi, Masaki Imai, Stanley Perlman, Richard Webby, Robert Seder, Mehul Suthar, Adolfo Garcia-Sastre, Michael Schotsaert, Tadaki Suzuki, Adrianus Boon, Yoshihiro Kawaoka, Daniel Douek, Juan Moliva, Nancy Sullivan, Matthew Gagne, Amy Ransier, James Case, Trushar Jeevan, John Franks, Thomas Fabrizio, Jennifer DeBeauchamp, Lisa Kercher, Patrick Seiler, Gagandeep Singh, Prajakta Warang, Ana S. Gonzalez-Reiche, Emilia Sordillo, Harm van Bakel, Viviana Simon
Publikováno v:
Research square.
Despite the development and deployment of antibody and vaccine countermeasures, rapidly-spreading SARS-CoV-2 variants with mutations at key antigenic sites in the spike protein jeopardize their efficacy. The recent emergence of B.1.1.529, the Omicron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c560099a71cec5a01788ce85fbf3ae30
https://pubmed.ncbi.nlm.nih.gov/35062015
https://pubmed.ncbi.nlm.nih.gov/35062015