Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Prajakta Khalkar"'
Autor:
Felicitas Bossler, Bianca J. Kuhn, Thomas Günther, Stephen J. Kraemer, Prajakta Khalkar, Svenja Adrian, Claudia Lohrey, Angela Holzer, Mitsugu Shimobayashi, Matthias Dürst, Arnulf Mayer, Frank Rösl, Adam Grundhoff, Jeroen Krijgsveld, Karin Hoppe-Seyler, Felix Hoppe-Seyler
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Hypoxia is linked to therapeutic resistance and poor clinical prognosis for many tumor entities, including human papillomavirus (HPV)-positive cancers. Notably, HPV-positive cancer cells can induce a dormant state under hypoxia, characterize
Externí odkaz:
https://doaj.org/article/918e7614f6584952bcd19da40a198aa4
Autor:
Deepika Nair, Emelie Rådestad, Prajakta Khalkar, Nuria Diaz-Argelich, Axel Schröder, Charlotte Klynning, Johanna Ungerstedt, Michael Uhlin, Aristi P. Fernandes
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Redox active selenium (Se) compounds at sub toxic doses act as pro-oxidants with cytotoxic effects on tumor cells and are promising future chemotherapeutic agents. However, little is known about how Se compounds affect immune cells in the tumor micro
Externí odkaz:
https://doaj.org/article/9e14d820710d43dda1c3b7f1d70ef30a
Autor:
Prajakta Khalkar, Nuria Díaz-Argelich, Juan Antonio Palop, Carmen Sanmartín, Aristi P. Fernandes
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2849 (2018)
Redox active selenium (Se) compounds have gained substantial attention in the last decade as potential cancer therapeutic agents. Several Se compounds have shown high selectivity and sensitivity against malignant cells. The cytotoxic effects are exer
Externí odkaz:
https://doaj.org/article/58354c01553e49d3a5415d7bae83f5be
Autor:
Ece Somuncular, Julia Hauenstein, Prajakta Khalkar, Anne-Sofie Johansson, Özge Dumral, Nicolai S. Frengen, Charlotte Gustafsson, Giuseppe Mocci, Tsu-Yi Su, Hugo Brouwer, Christine L. Trautmann, Michael Vanlandewijck, Stuart H. Orkin, Robert Månsson, Sidinh Luc
Publikováno v:
Stem cell reports. 17(7)
Hematopoiesis is maintained by functionally diverse lineage-biased hematopoietic stem cells (HSCs). The functional significance of HSC heterogeneity and the regulatory mechanisms underlying lineage bias are not well understood. However, absolute puri
Autor:
Ece Somuncular, Julia Hauenstein, Prajakta Khalkar, Özge Dumral, Anne-Sofie Johansson, Guiseppe Mocci, Charlotte Gustafsson, Nicolai Frengen, Tsu-Yi Su, Christine Trautmann, Hugo Brouwer, Michael Vanlandewijck, Stuart H. Orkin, Robert Månsson, Sidinh Luc
Publikováno v:
Experimental Hematology. 100:S103
Autor:
Felix Hoppe-Seyler, Arnulf Mayer, Mitsugu Shimobayashi, Prajakta Khalkar, Matthias Dürst, Stephen J. Kraemer, Bianca J. Kuhn, Felicitas Bossler, Svenja Adrian, Karin Hoppe-Seyler, Claudia Lohrey, Thomas Günther, Frank Rösl, Adam Grundhoff, Angela Holzer, Jeroen Krijgsveld
Publikováno v:
mBio, Vol 10, Iss 1, p e02323-18 (2019)
mBio
mBio, Vol 10, Iss 1 (2019)
mBio
mBio, Vol 10, Iss 1 (2019)
Oncogenic HPV types are major human carcinogens. Under hypoxia, HPV-positive cancer cells can repress the viral E6/E7 oncogenes and induce a reversible growth arrest. This response could contribute to therapy resistance, immune evasion, and tumor rec
Autor:
Aristi P. Fernandes, Nuria Díaz-Argelich, Carmen Sanmartín, Prajakta Khalkar, Juan Antonio Palop
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2849 (2018)
Volume 19
Issue 10
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2849 (2018)
Volume 19
Issue 10
Redox active selenium (Se) compounds have gained substantial attention in the last decade as potential cancer therapeutic agents. Several Se compounds have shown high selectivity and sensitivity against malignant cells. The cytotoxic effects are exer
Autor:
Julian Walfridsson, Sören Lehmann, Anni Martikainen, Prajakta Khalkar, Hani Abdulkadir Ali, Mohsen Karimi Arzenani, Johanna Ungerstedt, Aristi P. Fernandes, Nuria Díaz Argelich, Paula Codó
Publikováno v:
Free radical biologymedicine. 117
Selenium compounds have emerged as promising chemotherapeutic agents with proposed epigenetic effects, however the mechanisms and downstream effects are yet to be studied. Here we assessed the effects of the inorganic selenium compound selenite and t