Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Prajakta Kalkar"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Zoledronic acid (Zol) is a potent bisphosphonate that inhibits the differentiation of monocytes into osteoclasts. It is often used in combination with dexamethasone (Dex), a glucocorticoid that promotes the resolution of inflammation, to treat malign
Externí odkaz:
https://doaj.org/article/6a14a0dfa84048c589ecb2fa6d6d2555
Autor:
Swapnil Oak, Prajakta Kalkar, Sushil S Pawar, Prasad Sulkshane, Abhay Uthale, Tanuja Teni, Sudhir Nair, Rahul Patil, Priyanka Rajput, Harshada Wani, Sagar Pawar, Rohit Waghole, Pallavi Rane
Publikováno v:
Br J Cancer
Background Overexpression of anti-apoptotic MCL-1 protein in oral squamous cell carcinoma (OSCC) is linked to disease progression, therapy resistance and poor outcome. Despite its characteristic short half-life owing to ubiquitin-proteasome-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd4c199aab7451be7b431903611ec81
https://doi.org/10.1038/s41416-021-01421-x
https://doi.org/10.1038/s41416-021-01421-x
Autor:
Prajakta Kalkar, Zohar Zvi Zamir, Sagie Schif-Zuck, Sarit Larisch, Amiram Ariel, Orly Zeytuni-Timor, Naama Maimon
Publikováno v:
Apoptosis. 25:558-573
ARTS (Sept4_i2) is a pro-apoptotic protein and a product of the Sept4 gene. ARTS acts upstream of mitochondria to initiate caspase activation. ARTS induces apoptosis by specifically binding XIAP and allowing de-repression of active caspases required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad6b6d3b58c6ebb9d37e25e45acdfbd
https://doi.org/10.1007/s10495-020-01615-3
https://doi.org/10.1007/s10495-020-01615-3
Autor:
Rohan Chaubal, Amit Dutt, Nita S. Nair, Dimple Bhatia, Rajendra A. Badwe, Nisanth Mathew Raju, Vaibhav Vanmali, Shalaka Joshi, Nilesh Gardi, Farheen Naeem, Prajakta Kalkar, Rohini Hawaldar, Poonam Gera, Sudeep Gupta
Publikováno v:
Cancer Research. 77:4524-4524
Background: Hypoxia is defined as oxygen levels in tumor microenvironment of less than that in blood (90-100 mm Hg) and influences many aspects of tumour biology. During surgery tumour vasculature is cut off gradually leading to induction of acute hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e8c32e0132db17e9f18df83cc8f24d6
https://doi.org/10.1158/1538-7445.am2017-4524
https://doi.org/10.1158/1538-7445.am2017-4524