Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Prahlad Raninga"'
Autor:
Ensieh M. Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L. Bell, Federica Saletta, Felix V. Kohane, Daniel P. Neumann, Ye Zheng, Jourdin R. C. Rouaen, Toni Rose Jue, Filip T. Michniewicz, Piper Schadel, Erin Kasiou, Maria Tsoli, Giuseppe Cirillo, Shafagh Waters, Tyler Shai-Hee, Riccardo Cazzoli, Merryn Brettle, Iveta Slapetova, Maria Kasherman, Renee Whan, Fernando Souza-Fonseca-Guimaraes, Linda Vahdat, David Ziegler, John G. Lock, Federico M. Giorgi, KumKum Khanna, Orazio Vittorio
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Background Metastatic cancer cells exploit Epithelial-mesenchymal-transition (EMT) to enhance their migration, invasion, and resistance to treatments. Recent studies highlight that elevated levels of copper are implicated in cancer progressi
Externí odkaz:
https://doaj.org/article/b17391f9a29d4891bcdc6914896812f8
Autor:
Ajitha Sundaresan, Mai Le Ngoc, Marvell Ung Wew, Varsha Ramkumar, Prahlad Raninga, Rongji Sum, Ian Cheong
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
A screen for germination of Clostridium novyi-NT spores reveals that germinant sensing of this tumor-destructive anaerobic bacterium is stereoflexible for valine and its analogs and identifies co-germinants to improve germination efficacy in tumors.
Externí odkaz:
https://doaj.org/article/f3bf4aa474d94ad49d90e51b24dca205
Autor:
Murugan Kalimutho, Debottam Sinha, Deepak Mittal, Sriganesh Srihari, Devathri Nanayakkara, Shagufta Shafique, Prahlad Raninga, Purba Nag, Kate Parsons, Kum Kum Khanna
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-18 (2019)
Abstract Background Despite the increasing progress in targeted and immune based-directed therapies for other solid organ malignancies, currently there is no targeted therapy available for TNBCs. A number of mechanisms have been reported both in pre-
Externí odkaz:
https://doaj.org/article/6c2861ce8a7148f38470c80f4b435d58
Autor:
Paul B. Sinclair, Ruth E. Cranston, Prahlad Raninga, Joanna Cheng, Rebecca Hanna, Zoe Hawking, Steven Hair, Sarra L. Ryan, Amir Enshaei, Sirintra Nakjang, Vikki Rand, Helen J. Blair, Anthony V. Moorman, Olaf Heidenreich, Christine J. Harrison
Publikováno v:
Leukemia. 37:636-649
A common problem in the study of human malignancy is the elucidation of cancer driver mechanisms associated with recurrent deletion of regions containing multiple genes. Taking B-cell acute lymphoblastic leukaemia (B-ALL) and large deletions of 6q [d
Supplementary Figure 1 from NF-κB–Inhibited Acute Myeloid Leukemia Cells Are Rescued from Apoptosis by Heme Oxygenase-1 Induction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5368420de6d1bf4d1610810c61559c5
https://doi.org/10.1158/0008-5472.22387421.v1
https://doi.org/10.1158/0008-5472.22387421.v1
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5782 (2021)
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer lacking targeted therapy. Here, we evaluated the anti-cancer activity of APR-246, a P53 activator, and CX-5461, a RNA polymerase I inhibitor, in the treatment of TNBC cell
Externí odkaz:
https://doaj.org/article/2e3b1a6df19048d987dc64db6c1144ef
Autor:
Murugan Kalimutho, Debottam Sinha, Jessie Jeffery, Katia Nones, Sriganesh Srihari, Winnie C Fernando, Pascal HG Duijf, Claire Vennin, Prahlad Raninga, Devathri Nanayakkara, Deepak Mittal, Jodi M Saunus, Sunil R Lakhani, J Alejandro López, Kevin J Spring, Paul Timpson, Brian Gabrielli, Nicola Waddell, Kum Kum Khanna
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 9, Pp n/a-n/a (2018)
Abstract The centrosomal protein, CEP55, is a key regulator of cytokinesis, and its overexpression is linked to genomic instability, a hallmark of cancer. However, the mechanism by which it mediates genomic instability remains elusive. Here, we showe
Externí odkaz:
https://doaj.org/article/81a0772c1ea5410bbe8b8145afcfbc3d
Publikováno v:
Cancers, Vol 11, Iss 8, p 1073 (2019)
Claspin is essential for activating the DNA damage checkpoint effector kinase Chk1, a target in oncotherapy. Claspin functions are tightly correlated to Claspin protein stability, regulated by ubiquitin-dependent proteasomal degradation. Here we iden
Externí odkaz:
https://doaj.org/article/5fd7793420e8423ab650c0b00760eeb0
Autor:
Poursani, Ensieh M.1,2 (AUTHOR), Mercatelli, Daniele3 (AUTHOR), Raninga, Prahlad4 (AUTHOR), Bell, Jessica L.1,2 (AUTHOR), Saletta, Federica1,2 (AUTHOR), Kohane, Felix V.2,5 (AUTHOR), Neumann, Daniel P.2,5 (AUTHOR), Zheng, Ye2 (AUTHOR), Rouaen, Jourdin R. C.1,2 (AUTHOR), Jue, Toni Rose1,2 (AUTHOR), Michniewicz, Filip T.1,2 (AUTHOR), Schadel, Piper1,2 (AUTHOR), Kasiou, Erin1,2 (AUTHOR), Tsoli, Maria1 (AUTHOR), Cirillo, Giuseppe6 (AUTHOR), Waters, Shafagh2 (AUTHOR), Shai-Hee, Tyler1,2 (AUTHOR), Cazzoli, Riccardo1,7 (AUTHOR), Brettle, Merryn8 (AUTHOR), Slapetova, Iveta8 (AUTHOR)
Publikováno v:
Cell & Bioscience. 7/21/2023, Vol. 13 Issue 1, p1-19. 19p.
Autor:
Sundaresan, Ajitha1,2 (AUTHOR), Le Ngoc, Mai3 (AUTHOR), Wew, Marvell Ung3 (AUTHOR), Ramkumar, Varsha3 (AUTHOR), Raninga, Prahlad1 (AUTHOR), Sum, Rongji1,2 (AUTHOR), Cheong, Ian1,2 (AUTHOR) ian@tll.org.sg
Publikováno v:
Communications Biology. 1/28/2023, Vol. 6 Issue 1, p1-15. 15p.