Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Prahlad Parajuli"'
Autor:
Sneha Singh, Faraz Ahmad, Hariprasad Aruri, Susmita Das, Prahlad Parajuli, Navnath S. Gavande, Pawan Kumar Singh, Ashok Kumar
Publikováno v:
Virus Research, Vol 347, Iss , Pp 199419- (2024)
Zika virus (ZIKV) is a re-emerging RNA virus that is known to cause ocular and neurological abnormalities in infants. ZIKV exploits autophagic processes in infected cells to enhance its replication and spread. Thus, autophagy inhibitors have emerged
Externí odkaz:
https://doaj.org/article/064b2bad8bfc4416880d4cdf4a3fbfee
Autor:
Jennifer B. Jacob, Kuang-Chung Wei, Gerold Bepler, Joyce D. Reyes, Andi Cani, Lisa Polin, Kathryn White, Seongho Kim, Nerissa Viola, Julie McGrath, Anthony Guastella, CongCong Yin, Qing-Shen Mi, Benjamin L. Kidder, Kay-Uwe Wagner, Stuart Ratner, Victoria Phillips, Joanne Xiu, Prahlad Parajuli, Wei-Zen Wei
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106320- (2023)
Summary: HER2-targeted therapy has improved breast cancer survival, but treatment resistance and disease prevention remain major challenges. Genes that enable HER2/Neu oncogenesis are the next intervention targets. A bioinformatics discovery platform
Externí odkaz:
https://doaj.org/article/ef28e19612ea43f89c00bb93371e0760
Publikováno v:
Tissue Engineering Part A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a69a5349dd86b21454aae84cbf1677b
https://doi.org/10.1089/ten.tea.2022.0205
https://doi.org/10.1089/ten.tea.2022.0205
Autor:
Prahlad Parajuli, Rayna Rosati, Hirva Mamdani, Robert E Wright, Zahin Hussain, Aroma Naeem, Sijana Dzinic, Lisa Polin, Navnath Gavande, Manohar Ratnam
There is a need to improve response rates of immunotherapies in lung adenocarcinoma (AC). Extended (7–14 day) treatment of high glucocorticoid receptor (GR) expressing lung AC cells with dexamethasone (Dex) induces an irreversible senescence phenot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0058e35babec4f97b58ca16a0d80e415
https://doi.org/10.21203/rs.3.rs-1874725/v1
https://doi.org/10.21203/rs.3.rs-1874725/v1
Publikováno v:
Medicinal Plants for Cosmetics, Health and Diseases ISBN: 9781003108375
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::859d9b910838c820510267ac8c03798b
https://doi.org/10.1201/9781003108375-11
https://doi.org/10.1201/9781003108375-11
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 91
Tumor cells predominantly express self-antigens and overcoming self-tolerance is the primary challenge to effective immunotherapy. Tumors also express ligands for co-inhibitory molecules on immune cells, in order to suppress anti-tumor immunity. Over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7c449fe122b51b1ce6dcb5584edba0f
https://pubmed.ncbi.nlm.nih.gov/34099106
https://pubmed.ncbi.nlm.nih.gov/34099106
Autor:
Uma Shankar Shivhare, Bhupinder Singh, Prahlad Parajuli, Prashant Kesharwani, Ashay Jain, Gargi Ghoshal, Vijay Mishra, Om Prakash Katare, Atul Jain
Publikováno v:
Drug Discovery Today. 23:960-973
Galactosylated nanocarriers have recently emerged as viable and versatile tools to deliver drugs at an optimal rate specifically to their target tissues or cells, thus maximizing their therapeutic benefits while circumventing off-target effects. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f9c1d22d2b573bbef1aa146d79ef0b
https://doi.org/10.1016/j.drudis.2017.11.003
https://doi.org/10.1016/j.drudis.2017.11.003
Autor:
Cong-Cong Yin, Elizabeth A. Rondini, K Wagner, Joyce D. Reyes, James G. Granneman, Prahlad Parajuli, Jennifer B. Jacob, Wei-Zen Wei, Kuang Wei, Qing-Sheng Mi
Publikováno v:
Cancer Research. 81:2920-2920
Although humans are heterogeneous, evaluation of tumorigenesis and immunotherapy has relied on the use of inbred mouse strains, which may lead to biased results. In order to investigate the effect(s) of genetic background on tumor incidence and immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1941f8c1f0df6204a2194ef99fe248e9
https://doi.org/10.1158/1538-7445.am2021-2920
https://doi.org/10.1158/1538-7445.am2021-2920
Publikováno v:
Medicinal Plants ISBN: 9783030312688
Most forms of conventional cancer treatments are accompanied by undesirable side effects. Moreover, due to tumor heterogeneity, resistance to treatment and subsequent recurrence is often inevitable. Therefore, there is a need for development of progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08ec40e898675b52642d2a48ff2cc30e
https://doi.org/10.1007/978-3-030-31269-5_12
https://doi.org/10.1007/978-3-030-31269-5_12
This book offers a fresh look on a variety of issues concerning herbal medicine - the methods of growing and harvesting various medicinal plants; their phytochemical content; medicinal usage; regulatory issues; and mechanism of action against myriad