Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Prahlad K. Rao"'
Autor:
Erin J. Stephenson, Amanda S. Stayton, Aarti Sethuraman, Prahlad K. Rao, Alice Meyer, Charles Klazer Gomes, Molly C. Mulcahy, Liam McAllan, Michelle A. Puchowicz, Joseph F. Pierre, Dave Bridges, Joan C. Han
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Dietary sugar intake may contribute to the development non-alcoholic fatty liver disease. Here the authors investigated the effects of chronic dietary sucrose on the liver-adipose-microbiome axis in mice, and report that sex is a moderating factor th
Externí odkaz:
https://doaj.org/article/3fba10da99634f7895ece1db8569a6fc
Autor:
Prahlad K. Rao, Kate Merath, Eugene Drigalenko, Avinash Y. L. Jadhav, Richard A. Komorowski, Matthew I. Goldblatt, Anand Rohatgi, Mark A. Sarzynski, Samer Gawrieh, Michael Olivier
Publikováno v:
Clinical Proteomics, Vol 15, Iss 1, Pp 1-9 (2018)
Abstract Background Metabolic diseases such as obesity and diabetes are associated with changes in high-density lipoprotein (HDL) particles, including changes in particle size and protein composition, often resulting in abnormal function. Recent stud
Externí odkaz:
https://doaj.org/article/75780205fac44129ae8958577d1a86dd
Autor:
Prahlad K. Rao, Qingbo Li
Publikováno v:
Molecules, Vol 14, Iss 9, Pp 3237-3258 (2009)
Understanding the biology of Mycobacterium tuberculosis is one of the primary challenges in current tuberculosis research. Investigation of mycobacterial biology using the systems biology approach has deciphered much information with regard to the ba
Externí odkaz:
https://doaj.org/article/67cba915837748a3b6c0ebb2b56ba5f9
Autor:
Kent A. Willis, Erin J. Stephenson, Joan C. Han, Eugene B. Chang, Tahliyah S. Mims, Michelle Puchowicz, Joseph F. Pierre, Charles K. Gomes, Qusai Al Abdallah, Dengping Yin, Dejan Micic, E. Richard Moran, Ankush Gosain, Prahlad K. Rao, Ajay J. Talati
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 318:G322-G335
Bile acid receptors regulate the metabolic and immune functions of circulating enterohepatic bile acids. This process is disrupted by administration of parenteral nutrition (PN), which may induce progressive hepatic injury for unclear reasons, especi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732cd4e6d7cb90e1c588f4ade758a513
https://doi.org/10.1152/ajpgi.00216.2019
https://doi.org/10.1152/ajpgi.00216.2019
Autor:
Jeremy P. Glenn, Kylie Kavanagh, Prahlad K. Rao, Vivek Das, Laura A Cox, Zeeshan Hamid, Michael Olivier, Jeannie Chan, Avinash Y. L. Jadhav, Ellen E. Quillen, Genesio M. Karere
BackgroundDietary high fructose (HFr) is a known metabolic disruptor contributing to development of obesity and diabetes in Western societies. Initial molecular changes from exposure to HFr on liver metabolism may be essential to understand the pertu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2abca646c86fb5c8ffca5999d939604
https://doi.org/10.1101/2021.09.02.458361
https://doi.org/10.1101/2021.09.02.458361
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030482367
Hypoxia inducible factor alpha (HIF1α) is associated with neuroprotection conferred by diet-induced ketosis, but the underlying mechanism remains unclear. In this study, we use a ketogenic diet in rodents to induce a metabolic state of chronic ketos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1d9a4e15648308bcb0fd8e93693aeb3
https://doi.org/10.1007/978-3-030-48238-1_1
https://doi.org/10.1007/978-3-030-48238-1_1
Autor:
Erin J. Stephenson, Amanda S. Stayton, Aarti Sethuraman, Prahlad K. Rao, Alice Meyer, Charles Klazer Gomes, Molly C. Mulcahy, Liam McAllan, Michelle A. Puchowicz, Joseph F. Pierre, Dave Bridges, Joan C. Han
Publikováno v:
Nature communications. 13(1)
Almost all effective treatments for non-alcoholic fatty liver disease (NAFLD) involve reduction of adiposity, which suggests the metabolic axis between liver and adipose tissue is essential to NAFLD development. Since excessive dietary sugar intake m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a3cc776ea1cee5ffd25c1ff3cb8983
https://pubmed.ncbi.nlm.nih.gov/36229459
https://pubmed.ncbi.nlm.nih.gov/36229459
Autor:
Prahlad K. Rao, Aarti Sethuraman, Michelle Puchowicz, Joseph F. Pierre, Liam McAllan, Dave Bridges, Molly C. Mulcahy, Amanda S. Stayton, Erin J. Stephenson, Joan C. Han, Charles K. Gomes
SummaryAlmost all effective treatments for non-alcoholic fatty liver disease (NAFLD) involve reduction of adiposity, which suggests the metabolic axis between liver and adipose tissue is essential to NAFLD development. Since excessive dietary sugar i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf719ee2046b2ed013265495fdc8faa8
https://doi.org/10.1101/2020.05.20.106922
https://doi.org/10.1101/2020.05.20.106922
Autor:
Michelle Puchowicz, Joseph F. Pierre, Yuxin Li, Prahlad K. Rao, Rui Xu, Eugene B. Chang, Charles K. Gomes, E. Richard Moran, Dengping Yin
Activation of bile acid (BA) receptor, farnesoid X receptor (FXR) has been shown to inhibit inflammatory responses and improve tissue ischemia-reperfusion injury (IRI). This study investigated the effect of FXR deficiency on liver IRI, using a liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea8556cc11e8d03059a42ac95a90bc4
https://doi.org/10.1101/739839
https://doi.org/10.1101/739839
Publikováno v:
Obesity (Silver Spring, Md.)
Objective The current study investigated whether bile diversion (BD) improves metabolic phenotype under farnesoid X receptor (FXR) deficiency. Methods BD was performed in high-fat diet (HFD)-fed FXR knockout (FXRko) and wild-type (WT) animals. Metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b930fbc6cca23d92d6b13344c0f87629
https://doi.org/10.1002/oby.22440
https://doi.org/10.1002/oby.22440