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Akademický článek

ATM Modulates Nuclear Mechanics by Regulating Lamin A Levels

Autor: Pragya Shah, Connor W. McGuigan, Svea Cheng, Claire Vanpouille-Box, Sandra Demaria, Robert S. Weiss, Jan Lammerding

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Ataxia-telangiectasia mutated (ATM) is one of the three main apical kinases at the crux of DNA damage response and repair in mammalian cells. ATM activates a cascade of downstream effector proteins to regulate DNA repair and cell cycle checkpoints in

Externí odkaz: https://doaj.org/article/02137a9097b9435abda29067b4c83136

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Akademický článek

Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration

Autor: Sachi Horibata, Katherine E. Rogers, David Sadegh, Lynne J. Anguish, John L. McElwee, Pragya Shah, Paul R. Thompson, Scott A. Coonrod

Publikováno v: BMC Cancer, Vol 17, Iss 1, Pp 1-14 (2017)

Abstract Background Penetration of the mammary gland basement membrane by cancer cells is a crucial first step in tumor invasion. Using a mouse model of ductal carcinoma in situ, we previously found that inhibition of peptidylarginine deiminase 2 (PA

Externí odkaz: https://doaj.org/article/d9a675c1b2e046f6bd09b54431d25c0c

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Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

Autor: Emily S. Bell, Pragya Shah, Noam Zuela-Sopilniak, Dongsung Kim, Alice-Anais Varlet, Julien L.P. Morival, Alexandra L. McGregor, Philipp Isermann, Patricia M. Davidson, Joshua J. Elacqua, Jonathan N. Lakins, Linda Vahdat, Valerie M. Weaver, Marcus B. Smolka, Paul N. Span, Jan Lammerding

Publikováno v: Oncogene, 41, 4211-4230
Oncogene, 41, 36, pp. 4211-4230
Oncogene

Contains fulltext : 283431.pdf (Publisher’s version ) (Closed access) Aberrations in nuclear size and shape are commonly used to identify cancerous tissue. However, it remains unclear whether the disturbed nuclear structure directly contributes to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70d1cbcd6f62c9638cc7b792ccc5bd7
https://doi.org/10.1038/s41388-022-02420-9

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PP2A methylesterase PME ‐1 suppresses anoikis and is associated with therapy relapse of PTEN ‐deficient prostate cancers

Autor: Anna Aakula, Aleksi Isomursu, Christian Rupp, Andrew Erickson, Nikhil Gupta, Otto Kauko, Pragya Shah, Artur Padzik, Yuba Raj Pokharel, Amanpreet Kaur, Song‐Ping Li, Lloyd Trotman, Pekka Taimen, Antti Rannikko, Jan Lammerding, Ilkka Paatero, Tuomas Mirtti, Johanna Ivaska, Jukka Westermarck

Publikováno v: Molecular Oncology.

While organ-confined prostate cancer (PCa) is mostly therapeutically manageable, metastatic progression of PCa remains an unmet clinical challenge. Resistance to anoikis, a form of cell death initiated by cell detachment from the surrounding extracel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93cd49e95e4304ad6b9f45f3b1a4bca1
https://doi.org/10.1002/1878-0261.13353

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How Phytoremediator Plants Showing Potential of Maximum Remediation of Heavy Metals

Autor: Pragya Shah

Publikováno v: International Journal for Research in Applied Science and Engineering Technology. 10:1537-1539

The original laboratory work done by Pragya Shah on Phytoremediation technology shows that Phytoremediator plants have maximum capacity of Phytoremediation technique.Heavy metal like lead Pb, cadmium Cd, Cr ie Chromium are dangerous for living beings

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::768c3f6d61c576657fb5308218781dc0
https://doi.org/10.22214/ijraset.2022.46858

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Author response for 'PP2A methylesterase PME ‐1 suppresses anoikis and is associated with therapy relapse of PTEN ‐deficient prostate cancers'

Autor: null Anna Aakula, null Aleksi Isomursu, null Christian Rupp, null Andrew Erickson, null Nikhil Gupta, null Otto Kauko, null Pragya Shah, null Artur Padzik, null Yuba Raj Pokharel, null Amanpreet Kaur, null Song‐Ping Li, null Lloyd Trotman, null Pekka Taimen, null Antti Rannikko, null Jan Lammerding, null Ilkka Paatero, null Tuomas Mirtti, null Johanna Ivaska, null Jukka Westermarck

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67e8bf84b1dd4494be5f9f6b958fb2fa
https://doi.org/10.1002/1878-0261.13353/v2/response1

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Vulnerability of facial attractiveness perception to early and multi-year visual deprivation

Autor: Priti Gupta, Pragya Shah, Swochchhanda Shrestha, Sharon Gilad‐Gutnick, Suma Ganesh, Tapan Gandhi, Pawan Sinha

Publikováno v: Developmental scienceREFERENCES. 26(1)

Judgments of facial attractiveness invariably accompany our perception of faces. Even neonates appear to be capable of making such judgments in a manner consistent with adults. This suggests that the processes supporting facial attractiveness require

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb089b63004d41b81aadc96bf126986b
https://pubmed.ncbi.nlm.nih.gov/35340087

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