Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Praful B. Deshpande"'
Autor:
Gopal Venkatesh Shavi, Srinivas Mutalik, Praful B. Deshpande, Nayanabhirama Udupa, Ranjith Kumar Averineni, Prashant B Musmade, Amruta Deshpande, Meka Sreenivasa Reddy, Aravind Kumar Gurram, Karthik Arumugam
Publikováno v:
Life Sciences. 162:125-137
Aim The aim of the present study was to develop nanoproliposomes of lercanidipine, in order to overcome its poor biopharmaceutical properties and to improve its therapeutic efficacy in treating hypertension. Main methods The nanoproliposomes were pre
Autor:
Naseer Maliyakkal, Nayanabhirama Udupa, Praful B. Deshpande, Usha Y. Nayak, B. Shrawan, Gopal Venkatesh Shavi, Averineni Ranjith Kumar, Ramesh Raghavendra, Meka Sreenivasa Reddya
Publikováno v:
Life Sciences. 141:143-155
Aim: Formulation and evaluation of anastrozole, an anti-cancer drug loaded in different biodegradable polymeric nanoparticles. Materials and methods: Different carrier systems such as poly(lactide-co-glycolide) (PLGA 50:50), poly(lacticacid) (PLA) an
Publikováno v:
Journal of Pharmaceutical Innovation. 10:374-387
The aim of present research work was to develop self microemulsifying drug delivery system (SMEDDS) to improve the oral bioavailability of lercanidipine hydrochloride and to evaluate the effect of surfactant on the microemulsion existing area in the
Autor:
Nitesh Kumar, C. Mallikarjuna Rao, Neetinkumar D. Reddy, P. Vasanth Raj, Praful B. Deshpande, Nayanabhirama Udupa, Amita Rai, Geetha Mathew, N. Gopalan Kutty, Prateek Jain
Publikováno v:
Pharmacological Reports. 66:788-798
Background Silymarin, a hepatoprotective agent, has poor oral bioavailability. However, the current dosage form of the drug does not target the liver and inflammatory cells selectively. The aim of the present study was to develop lecithin-based carri
Autor:
Nayanabhirama Udupa, Kranti P Musmade, M. Sreenivasa Reddy, A. Ranjith Kumar, M. Naseer Maliyakkal, Prashant B Musmade, Praful B. Deshpande
Publikováno v:
Bulletin of Materials Science. 37:945-951
Nanoparticles represent one of the attractive alternatives in the effective treatment of cancer chemotherapy. In the present work, formulation and development of a novel methotrexate (MTX)-loaded biodegradable nanoparticles using poly(D,L-lactide-co-
Autor:
Kiran Avadhani, Srinivas Mutalik, Raghavendra V. Kulkarni, Pallavi K. Shetty, Neelam A. Suthar, Praful B. Deshpande, Jyothsna Menon
Publikováno v:
Current Drug Delivery. 10:427-434
The effects of permeation enhancers and sonophoresis on the transdermal permeation of lercanidipine hydrochloride (LRDP) across mouse skin were investigated. Parameters including drug solubility, partition coefficient, drug degradation and drug perme
Autor:
Nayanabhirama Udupa, Gopal Venkatesh Shavi, Praful B. Deshpande, Satya S. Sadhu, Usha Y. Nayak, Ramesh Raghavendra, Cyril Danilenkoff, Ranjith Kumar Averineni, Kishore Ginjupalli, Meka Sreenivasa Reddy
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 75
The purpose of the present study was to fabricate PLGA 50:50 and PLA microspheres for controlled delivery of anastrozole. The microspheres were prepared by oil-in-water (o/w) emulsion/solvent evaporation technique and evaluated for particle size and
Autor:
Aravind Kumar Gurram, Naseer Maliyakkal, Gopal V. Shavi, Praful B. Deshpande, Udupa Nayanabhirama, Karthik Arumugam, Sreenivasa R Meka, Ranjith Kumar Averineni
Publikováno v:
Bulletin of Materials Science. 35:319-326
Clinical administration of paclitaxel is hindered due to its poor solubility, which necessitates the formulation of novel drug delivery systems to deliver such extreme hydrophobic drug. To formulate nanoparticles which makes suitable to deliver hydro
Autor:
Prashant B Musmade, Nayanabhirama Udupa, Kranti B. Talole, Praful B. Deshpande, Shriram M. Pathak, Arumugam Karthik, Sureshwar Pandey
Publikováno v:
Arzneimittelforschung. 61:23-31
The need for a reliable bioanalytical method is of primary importance during preclinical studies. The aim of the present study was simultaneous determination of pioglitazone (CAS 111025-46-8) (PIO) and glimepiride (CAS 93479-97-1) (GLM) in plasma of
Autor:
Meka Sreenivasa Reddy, Nayanabhirama Udupa, G. Aravind Kumar, Praful B. Deshpande, Gopal Venkatesh Shavi, Arumugam Karthik, Averineni Ranjith Kumar
Publikováno v:
PDA Journal of Pharmaceutical Science and Technology. 65:333-344
In light of environmental apprehension, supercritical fluid technology (SFT) exhibits excellent opportunities to accomplish key objectives in the drug delivery sector. Supercritical fluid extraction using carbon dioxide (CO2) has been recognized as a