Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Pradyut K. Paul"'
Autor:
Rahul Das, Jayeeta Giri, Pradyut K. Paul, Nicole Froelich, Raghavan Chinnadurai, Sara McCoy, Wade Bushman, Jacques Galipeau
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-16 (2022)
Abstract Adipogenic differentiation of visceral adipose tissue-resident multipotent mesenchymal stromal cells (VA-MSC) into adipocytes is metabolically protective. Under chronic inflammatory stress, this neoadipogenesis process is suppressed by vario
Externí odkaz:
https://doaj.org/article/94ed8962d64847708cc2df08326912ee
Autor:
Pradyut K. Paul, Rahul Das, Travis Drow, Emily A. Nylen, Arnaldo Henrique de Souza, Zunyi Wang, Michael W. Wood, Dawn B. Davis, Dale E. Bjorling, Jacques Galipeau
Publikováno v:
American Journal of Transplantation. 22:2571-2585
Allogeneic islet transplantation is a promising experimental therapy for poorly controlled diabetes. Despite pharmacological immunosuppression, long-term islet engraftment remains elusive. Here, we designed a synthetic fusion transgene coupling PD-L1
Autor:
Pradyut K Paul, Rahul Das, Travis J Drow, Arnaldo H de Souza, Appakalai N Balamurugan, Dawn Belt Davis, Jacques Galipeau
Publikováno v:
Stem Cells Translational Medicine. 11:630-643
Preserving islet health and function is critical during pretransplant culture to improve islet transplantation outcome and for ex vivo modeling of diabetes for pharmaceutical drug discovery. The limited islet engraftment potential is primarily attrib
Autor:
Pradyut K. Paul, Rahul Das, Travis Drow, Emily A. Nylen, Arnaldo Henrique de Souza, Zunyi Wang, Michael W. Wood, Dawn B. Davis, Dale E. Bjorling, Jacques Galipeau
Publikováno v:
American Journal of Transplantation. 23:693
Autor:
Mark P Keller, Pradyut K Paul, Mary E Rabaglia, Donnie S Stapleton, Kathryn L Schueler, Aimee Teo Broman, Shuyun Isabella Ye, Ning Leng, Christopher J Brandon, Elias Chaibub Neto, Christopher L Plaisier, Shane P Simonett, Melkam A Kebede, Gloria M Sheynkman, Mark A Klein, Nitin S Baliga, Lloyd M Smith, Karl W Broman, Brian S Yandell, Christina Kendziorski, Alan D Attie
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006466 (2016)
Human genome-wide association studies (GWAS) have shown that genetic variation at >130 gene loci is associated with type 2 diabetes (T2D). We asked if the expression of the candidate T2D-associated genes within these loci is regulated by a common loc
Externí odkaz:
https://doaj.org/article/a7a38973596a4970afaa372927d78706
Autor:
Jayeeta Giri, Pradyut K. Paul, Yun Liang, Maxwell Parker, Sara S. McCoy, Jacques Galipeau, Rahul Das, Andrea Pennati
Publikováno v:
Cytotherapy
Background aims Mesenchymal stromal cells (MSCs) provide minor salivary glands (MSGs) with support and niche cells for epithelial glandular tissue. Little is known about resident MSG-derived MSCs (MSG-MSCs) in primary Sjӧgren's syndrome (PSS). The a
Autor:
Rahul Das, Jayeeta Giri, Pradyut K. Paul, Nicole Froelich, Raghavan Chinnadurai, Sara McCoy, Wade Bushman, Jacques Galipeau
Publikováno v:
NPJ Regenerative medicine. 7(1)
Adipogenic differentiation of visceral adipose tissue-resident multipotent mesenchymal stromal cells (VA-MSC) into adipocytes is metabolically protective. Under chronic inflammatory stress, this neoadipogenesis process is suppressed by various pro-in
Autor:
Pradyut K. Paul, Rahul Das, T. Drow, Dawn Belt Davis, B. Appakalai, A. de Souza, Jacques Galipeau
Publikováno v:
Cytotherapy. 23:S31-S32
Autor:
Donald S. Stapleton, Peter W. Lewis, Mary E. Rabaglia, Ning Leng, Chen-Yu Wang, Mark P. Keller, Pradyut K. Paul, Christina Kendziorski, Alan D. Attie
Publikováno v:
Cell Cycle. 15:3191-3202
Anti-silencing function 1 (ASF1) is a histone H3-H4 chaperone involved in DNA replication and repair, and transcriptional regulation. Here, we identify ASF1B, the mammalian paralog to ASF1, as a proliferation-inducing histone chaperone in human β-ce
Autor:
Claire C. Baniel, Zachary S. Morris, Paul M. Sondel, Jacques Galipeau, Erin J. Nystuen, Elizabeth G. Sumiec, Sarah E. Emma, Amy K. Erbe, Amber M. Bates, Pradyut K. Paul, Alexander L. Rakhmilevich
Publikováno v:
Cancer Research. 80:902-902
We have recently demonstrated the effectiveness of combining external beam radiation therapy (RT), intratumoral immunocytokine (IT-IC), and anti-CTLA4 (αCTLA4) in eliminating large (500mm3) B78 melanomas (MEL), prolonging survival and invoking T cel