Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Pradyumna Harlapur"'
Autor:
Anna Niarakis, Reinhard Laubenbacher, Gary An, Yaron Ilan, Jasmin Fisher, Åsmund Flobak, Kristin Reiche, María Rodríguez Martínez, Liesbet Geris, Luiz Ladeira, Lorenzo Veschini, Michael L. Blinov, Francesco Messina, Luis L. Fonseca, Sandra Ferreira, Arnau Montagud, Vincent Noël, Malvina Marku, Eirini Tsirvouli, Marcella M. Torres, Leonard A. Harris, T. J. Sego, Chase Cockrell, Amanda E. Shick, Hasan Balci, Albin Salazar, Kinza Rian, Ahmed Abdelmonem Hemedan, Marina Esteban-Medina, Bernard Staumont, Esteban Hernandez-Vargas, Shiny Martis B, Alejandro Madrid-Valiente, Panagiotis Karampelesis, Luis Sordo Vieira, Pradyumna Harlapur, Alexander Kulesza, Niloofar Nikaein, Winston Garira, Rahuman S. Malik Sheriff, Juilee Thakar, Van Du T. Tran, Jose Carbonell-Caballero, Soroush Safaei, Alfonso Valencia, Andrei Zinovyev, James A. Glazier
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Digital twins represent a key technology for precision health. Medical digital twins consist of computational models that represent the health state of individual patients over time, enabling optimal therapeutics and forecasting patient prog
Externí odkaz:
https://doaj.org/article/c925f2072b8448f08b5b01c6a74dc959
Autor:
Pradyumna Harlapur, Atchuta Srinivas Duddu, Kishore Hari, Prakash Kulkarni, Mohit Kumar Jolly
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1842 (2022)
Elucidating the design principles of regulatory networks driving cellular decision-making has important implications for understanding cell differentiation and guiding the design of synthetic circuits. Mutually repressing feedback loops between ‘ma
Externí odkaz:
https://doaj.org/article/9f2cacb02ea449f8822be34576eab2b2
Among the different microsatellite sequences found in the human genome, the dinucleotide TG/CA repeats are one of the most abundant, exhibiting multifaceted functional roles. Availability of several primate genomes offers relevant datasets for studyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02e1352fa64ab9fff0a22a717640bf3c
https://doi.org/10.1101/2023.05.09.539941
https://doi.org/10.1101/2023.05.09.539941
Autor:
Kishore Hari, Pradyumna Harlapur, Aashna Saxena, Aishwarya Girish, Herbert Levine, Mohit Kumar Jolly
Cell-fate decisions are driven by complex regulatory networks. Despite their complexity, these networks often exhibit low-dimensional dynamics and allow only a limited number of phenotypes. What design principles in network topology allow for these s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c2affaf239f09e2ec175367bfceeecf
https://doi.org/10.1101/2023.02.03.526930
https://doi.org/10.1101/2023.02.03.526930
Autor:
Kishore Hari, Pradyumna Harlapur, Aditi Gopalan, Varun Ullanat, Atchuta Srinivas Duddu, Mohit Kumar Jolly
Publikováno v:
Journal of biosciences. 47
Understanding the dynamical hallmarks of network motifs is one of the fundamental aspects of systems biology. Positive feedback loops constituting one or two nodes - self-activation, toggle switch, and double activation loops - are the commonly obser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c48eba05522777c31bfe28020e59276
https://pubmed.ncbi.nlm.nih.gov/36550692
https://pubmed.ncbi.nlm.nih.gov/36550692
Autor:
Prajwal Bharadwaj, Divya Mondhe, Rucha Kulkarni, Radha Kulkarni, Talha Kamran Khan, Prerita Chawla, Shubhankar Dash, Kritjgnan Bhardwaj, Shreeya Raich, Yashna Khakre, M Sreepadmanabh, Shinto James, Siddhant Shetty, Pradyumna Harlapur, Ramesh Adakkattil, Manali Powar, Tushar Patel, Saloni Chopra, Anish Ganju, Kallol Mozumdar
Low intrinsic stability has marred the production of psychrophilic proteins in commonly used mesophilic systems. This may lead to a lopsided bias towards the expression of the few psychrophilic proteins which can manage a stable structure at those te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55e2c239b1df630e0d1038e4ef95506a
https://doi.org/10.14293/s2199-1006.1.sor-.ppmewlw.v1
https://doi.org/10.14293/s2199-1006.1.sor-.ppmewlw.v1