Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Pradipta R, Ray"'
Publikováno v:
Physiological Reports, Vol 10, Iss 3, Pp n/a-n/a (2022)
Abstract Sedentary lifestyle, chronic disease, or microgravity can cause muscle deconditioning that then has an impact on other physiological systems. An example is the nervous system, which is adversely affected by decreased physical activity result
Externí odkaz:
https://doaj.org/article/9b505b9fa97f4907aa5d418f911cad1e
Autor:
Keira J A Johnston, Joey Ward, Pradipta R Ray, Mark J Adams, Andrew M McIntosh, Blair H Smith, Rona J Strawbridge, Theodore J Price, Daniel J Smith, Barbara I Nicholl, Mark E S Bailey
Publikováno v:
PLoS Genetics, Vol 17, Iss 4, p e1009428 (2021)
Chronic pain is highly prevalent worldwide and imparts a significant socioeconomic and public health burden. Factors influencing susceptibility to, and mechanisms of, chronic pain development, are not fully understood, but sex is thought to play a si
Externí odkaz:
https://doaj.org/article/5334ddb9712849f0b68bcbc188bdb41a
Autor:
Pradipta R Ray, Stephanie Shiers, James P Caruso, Diana Tavares-Ferreira, Ishwarya Sankaranarayanan, Megan L Uhelski, Yan Li, Robert Y North, Claudio Tatsui, Gregory Dussor, Michael D Burton, Patrick M Dougherty, Theodore J Price
Publikováno v:
Brain
Neuropathic pain is a leading cause of high-impact pain, is often disabling and is poorly managed by current therapeutics. Here we focused on a unique group of neuropathic pain patients undergoing thoracic vertebrectomy where the dorsal root ganglia
Autor:
Pradipta R. Ray, Jawad Khan, Andi Wangzhou, Diana Tavares-Ferreira, Armen N. Akopian, Gregory Dussor, Theodore J. Price
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Sex differences in gene expression are important contributors to normal physiology and mechanisms of disease. This is increasingly apparent in understanding and potentially treating chronic pain where molecular mechanisms driving sex differences in n
Externí odkaz:
https://doaj.org/article/8bcbf372fa754264be65d107aa23680c
Autor:
Armen N. Akopian, Paulino Barragán-Iglesias, Andi Wangzhou, Galo L. Mejia, Stephanie Shiers, Diana Tavares-Ferreira, Salim Megat, Ishwarya Sankaranarayanan, Gregory Dussor, Ruta Uttarkar, Pradipta R. Ray, Theodore J. Price
Publikováno v:
Biol Psychiatry
BackgroundThere are clinically relevant sex differences in acute and chronic pain mechanisms, but we are only beginning to understand their mechanistic basis. Transcriptome analyses of rodent whole dorsal root ganglion (DRG) have revealed sex differe
Autor:
Pradipta R. Ray, Tarjani Shukla, June Bryan de la Peña, Jason D. Shepherd, Sarah Loerch, Lokesh Basavarajappa, Paulino Barragán-Iglesias, Salim Megat, Jane Song, Zachary T. Campbell, Nikesh Kunder, Andi Wanghzou, Kenneth Hoyt, Dominique James, Jamie K. Moy, Theodore J. Price, Oswald Steward, Tzu-Fang Lou
Publikováno v:
J Neurosci
Injury responses require communication between different cell types in the skin. Sensory neurons contribute to inflammation and can secrete signaling molecules that affect non-neuronal cells. Despite the pervasive role of translational regulation in
Autor:
Paulino Barragán-Iglesias, Zachary T. Campbell, Joseph J. Pancrazio, Pradipta R. Ray, Theodore J. Price, June Bryan de la Peña, Rahul Atmaramani, Tarjani Shukla, Bryan J. Black, Nikesh Kunder, Andi Wanghzou, Tzu-Fang Lou
Publikováno v:
Pain
Translational regulation permeates neuronal function. Nociceptors are sensory neurons responsible for the detection of harmful stimuli. Changes in their activity, termed plasticity, are intimately linked to the persistence of pain. Although inhibitor
Autor:
Amelia J. McFarland, Pradipta R. Ray, Steve Davidson, Muhammad Saad Yousuf, Gregory Dussor, Sanjay V. Neerukonda, Candler Paige, Michael D. Burton, Stephanie Shiers, Ishwarya Sankaranarayanan, Andi Wangzhou, Juliet Mwirigi, Nizar Ghneim, Diana Tavares-Ferreira, Theodore J. Price
Publikováno v:
Brain, Behavior, and Immunity
SSRN
SSRN
Highlights • Our paper identifies key neuro-immune interactions in the lungs of COVID-19 patients that potentially drive neurogenic pulmonary dysfunction. • Our framework uses an interactome prediction model to identify relevant ligand – recept
Autor:
Diana Tavares-Ferreira, Stephanie Shiers, Pradipta R. Ray, Andi Wangzhou, Vivekanand Jeevakumar, Ishwarya Sankaranarayanan, Anna M. Cervantes, Jeffrey C. Reese, Alexander Chamessian, Bryan A. Copits, Patrick M. Dougherty, Robert W. Gereau, Michael D. Burton, Gregory Dussor, Theodore J. Price
Publikováno v:
Sci Transl Med
Nociceptors are specialized sensory neurons that detect damaging or potentially damaging stimuli and are found in the dorsal root ganglia (DRG) and trigeminal ganglia. These neurons are critical for the generation of neuronal signals that ultimately
Autor:
Pradipta R. Ray, Megan L. Uhelski, Ishwarya Sankaranarayanan, Theodore J. Price, Stephanie Shiers, Yan Li, Andi Wangzhou, Patrick M. Dougherty, Claudio E. Tatsui, Laurence D. Rhines
Publikováno v:
Pain
SARS-CoV-2 has created a global crisis. COVID-19, the disease caused by the virus, is characterized by pneumonia, respiratory distress, and hypercoagulation and can be fatal. An early sign of infection is loss of smell, taste, and chemesthesis-loss o