Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Pradip K. Kamat"'
Autor:
Jenna L. Leclerc, Joshua M. Garcia, Matthew A. Diller, Anne-Marie Carpenter, Pradip K. Kamat, Brian L. Hoh, Sylvain Doré
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Non-traumatic subarachnoid hemorrhage (SAH) affects an estimated 30,000 people each year in the United States, with an overall mortality of ~30%. Most cases of SAH result from a ruptured intracranial aneurysm, require long hospital stays, and result
Externí odkaz:
https://doaj.org/article/df4a501fd69f4b008284713c743a16a8
Autor:
Patrick D. Lyden, Francesca Bosetti, Márcio A. Diniz, André Rogatko, James I. Koenig, Jessica Lamb, Karisma A. Nagarkatti, Ryan P. Cabeen, David C. Hess, Pradip K. Kamat, Mohammad B. Khan, Kristofer Wood, Krishnan Dhandapani, Ali S. Arbab, Enrique C. Leira, Anil K. Chauhan, Nirav Dhanesha, Rakesh B. Patel, Mariia Kumskova, Daniel Thedens, Andreia Morais, Takahiko Imai, Tao Qin, Cenk Ayata, Ligia S.B. Boisserand, Alison L. Herman, Hannah E. Beatty, Sofia E. Velazquez, Sebastian Diaz-Perez, Basavaraju G. Sanganahalli, Jelena M. Mihailovic, Fahmeed Hyder, Lauren H. Sansing, Raymond C. Koehler, Steven Lannon, Yanrong Shi, Senthilkumar S. Karuppagounder, Adnan Bibic, Kazi Akhter, Jaroslaw Aronowski, Louise D. McCullough, Anjali Chauhan, Andrew Goh, Shahneela Siddiqui, Kevin Sheth, Charles Matouk, Charles Dela Cruz, Jiangbing Zhou, Valina L. Dawson, Ted M. Dawson, Jian Liang, Peter C.M. van Zijl, Steven R. Zeiler, W. Taylor Kimberly, Taylan Erdogan, Lili Yu, Joseph Mandeville, Jonah Patrick Weigand Whittier
Publikováno v:
Stroke
Cerebral ischemia and reperfusion initiate cellular events in brain that lead to neurological disability. Investigating these cellular events provides ample targets for developing new treatments. Despite considerable work, no such therapy has transla
Publikováno v:
Stroke. 54
Background: Stroke leads to disability and death worldwide. There is evidence that stroke affects the immune system function, and the clock gene controls the immune system. Stroke elevates the inflammatory cascade. Immune response controls the stroke
Autor:
Andreia Morais, Joseph J. Locascio, Lauren H. Sansing, Jessica Lamb, Karisma Nagarkatti, Takahiko Imai, Klaus van Leyen, Jaroslaw Aronowski, James I. Koenig, Francesca Bosetti, Patrick Lyden, Cenk Ayata, Patrick D. Lyden, David C. Hess, Pradip K. Kamat, Mohammad Badruzzaman Khan, Krishnan Dhandapani, Ali S. Arbab, Shahneela Siddiqui, Cameron Smith, Mohammad Nisar, Enrique C. Leira, Anil K. Chauhan, Nirav Dhanesha, Rakesh B. Patel, Mariia Kumskova, Daniel Thedens, Kai Wang, Tao Qin, Xuyan Jin, Taylan Denis Erdogan, Lili Yu, Joseph B. Mandeville, William Taylor Kimberly, Jonah Patrick Weigand Whittier, Eng Lo, Ken Arai, Klaus Van Leyen, Fahmeed Hyder, Jelena M. Mihailovic, Basavaraju G. Sanganahalli, Sebastian Diaz-Perez, Sofia E. Velazquez, Hannah E. Beatty, Conor Johnson, Alison L. Herman, Ligia S. B. Boisserand, Emma Immakavar, Raymond C. Koehler, Ted Dawson, Valina Dawson, Yanrong Shi, Brooklyn Avery, Steven Lannon, Adnan Bibic, Kazi Akhter, Senthilkumar S. Karuppagounder, Louise D. McCullough, Lidiya Obertas, Andrew Goh, Shuning Huang, Anjali Chauhan
Publikováno v:
Stroke.
The Stroke Preclinical Assessment Network (SPAN) is a multicenter preclinical trial platform using rodent models of transient focal cerebral ischemia to address translational failure in experimental stroke. In addition to centralized randomization an
Publikováno v:
Stroke. 53
Background: Stroke is a leading cause of disability and death worldwide. There is evidence that there is a circadian rhythm in stroke with peak occurrence in the morning (6 to 10 am). However it is not clear if the size of infarcts and the outcomes o
Autor:
Lei Liu, Fúlvio R. Mendes, Arash Naziripour, Chris Li, Jenna L Leclerc, Abdullah Shafique Ahmad, Pradip K. Kamat, Damian Hernandez, Sylvain Doré
Publikováno v:
Journal of Alzheimer's Disease. 74:173-187
Background Neuroinflammation has been recognized as an important factor in the pathogenesis of Alzheimer's disease (AD). One of the most recognized pathways in mediating neuroinflammation is the prostaglandin E2-EP1 receptor pathway. Objective Here,
Autor:
Pradip K. Kamat, Mohammad Badruzzaman Khan, Cameron Smith, Shahneela Siddiqui, Babak Baban, Krishnan Dhandapani, David C. Hess
Publikováno v:
Neurochemistry International. 162:105457
The circadian system is widely involved in the various pathological outcomes affected by time dimension changes. In the brain, the master circadian clock, also known as the "pacemaker," is present in the hypothalamus's suprachiasmatic nucleus (SCN).
Publikováno v:
Stroke. 51
Introduction: Subarachnoid hemorrhage (SAH) is one of the most devastating forms of hemorrhagic stroke and it is a serious medical condition caused by bleeding of a ruptured aneurysm. The etiopathology of the disease includes early brain injury, vaso
Publikováno v:
Stroke. 51
Introduction: Clinical and experimental studies have linked the presence of oxidative damage and neuroinflammation from free hemoglobin (Hb) to the innate immune response. CD36 has been identified as a macrophage/microglia surface receptor as part of
Publikováno v:
Alcoholism: Clinical and Experimental Research. 40:2474-2481
Alcohol is the most socially accepted addictive drug. Alcohol consumption is associated with some health problems such as neurological, cognitive, behavioral deficits, cancer, heart and liver disease. Mechanisms of alcohol-induced toxicity are presen