Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Pradeep Thiyyagura"'
Publikováno v:
Heliyon, Vol 5, Iss 8, Pp e02216- (2019)
While tomographic neuroimaging data is information rich, objective, and with high sensitivity in the study of brain diseases such as Alzheimer's disease (AD), its direct use in clinical practice and in regulated clinical trial (CT) still has many cha
Externí odkaz:
https://doaj.org/article/dd63a4d1b69441c087ac29009c512847
Autor:
Yinghua Chen, Wendy Lee, Yi Su, Kewei Chen, Ryan Richholt, Matthew J. Huentelman, Sameena Syed, Dona E.C. Locke, Stefanie N. Velgos, Eric M. Reiman, Pradeep Thiyyagura, Richard J. Caselli, Cynthia M. Stonnington, Bai Lu
Publikováno v:
Journal of Alzheimer's Disease. 78:721-734
Background: Whether brain-derived neurotrophic factor (BDNF) Met carriage impacts the risk or progression of Alzheimer’s disease (AD) is unknown. Objective: To evaluate the interaction of BDNF Met and APOE4 carriage on cerebral metabolic rate for g
Autor:
Kaycee M Sink, Pierre N. Tariot, Nan Hu, Yakeel T. Quiroz, Michael Malek-Ahmadi, Eric M. Reiman, Yinghua Chen, Howard Mackey, Hillary Protas, Valentina Ghisays, William Cho, Kewei Chen, Heather Guthrie, Yi Su, Dhruman D. Goradia, Claudia Muñoz, Carlos Tobon, Qinshu Lian, Paul S. VanGilder, Ji Luo, Francisco Lopera, Wendy Lee, Paula Ospina, Yamile Bocanegra, Victoria Tirado, Eliana Henao, Silvia Rios-Romenets, Pradeep Thiyyagura, Jillian Smith, Ronald G. Thomas, Jessica B. Langbaum, Margarita Giraldo-Chica, Natalia Acosta-Baena
Publikováno v:
Alzheimer's & Dementia
Introduction The API AutosomalDominant AD (ADAD) Colombia Trial is a placebo‐controlled clinical trial of crenezumab in 252 cognitively unimpaired 30 to 60‐year‐old Presenilin 1 (PSEN1) E280A kindred members, including mutation carriers randomi
Autor:
Yinghua Chen, Dona E.C. Locke, Kewei Chen, Pradeep Thiyyagura, Cynthia M. Stonnington, Cary R. Savage, Richard J. Caselli, Sameen Sharieff, Robert Bauer, Eric M. Reiman, Wendy Lee, Gene E. Alexander
Publikováno v:
Journal of Alzheimer's Disease. 63:603-615
BACKGROUND: Brain imaging measurements can provide evidence of possible preclinical Alzheimer’s disease (AD). Their ability to predict individual imminent clinical conversion remains unclear. OBJECTIVE: To investigate the ability of pre-specified v
Publikováno v:
Heliyon
Heliyon, Vol 5, Iss 8, Pp e02216-(2019)
Heliyon, Vol 5, Iss 8, Pp e02216-(2019)
While tomographic neuroimaging data is information rich, objective, and with high sensitivity in the study of brain diseases such as Alzheimer's disease (AD), its direct use in clinical practice and in regulated clinical trial (CT) still has many cha
Autor:
Lishuang Shen, Yinghua Chen, Kewei Chen, Silvia Rios-Romenets, Yi Su, Henrik Zetterberg, Moiz Bootwalla, Michael J. O'Hare, Arabiye Artola, Pierre N. Tariot, John B Miller, Dhanesh Amarnani, Ana Baena, Gyungah Jun, Yakeel T. Quiroz, Juliana Acosta-Uribe, Rebecca Reiman, Pradeep Thiyyagura, Marcus Naymik, Kenneth S. Kosik, Aaron P. Schultz, Daniel J. Norton, Matthew J. Huentelman, Keith A. Johnson, Santiago Delgado-Tirado, Enmanuelle Pardilla-Delgado, Francisco Lopera, Reisa A. Sperling, Leo A. Kim, Natalia Chmielewska, Eric M. Reiman, Joseph F. Arboleda-Velasquez, Edmarie Guzmán-Vélez, Xiaowu Gai, Jianling Ji, David Aguillon, Matthew A. Lalli, Justin S. Sanchez, Kahira L. Saez-Torres, Claudia Marino, Kaj Blennow, David Leyton-Cifuentes, Margarita Giraldo, Ji Luo
Publikováno v:
Nature medicine
Nature medicine, vol 25, iss 11
Nature medicine, vol 25, iss 11
We identified a PSEN1 (presenilin 1) mutation carrier from the world's largest autosomal dominant Alzheimer's disease kindred, who did not develop mild cognitive impairment until her seventies, three decades after the expected age of clinical onset.
Autor:
Jonathan Krakoff, Pradeep Thiyyagura, Martin Reinhardt, Angelo Del Parigi, Eric M. Reiman, Kewei Chen, Maximilian G. Hohenadel, Duc Son N.T. Le, Christopher M. Weise
Publikováno v:
International journal of obesity (2005)
Prader–Willi syndrome (PWS) is a type of human genetic obesity that may give us information regarding the physiology of non-syndromic obesity. The objective of this study was to investigate the functional correlates of hunger and satiety in individ
Publikováno v:
Alzheimer's & Dementia. 14
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
Hillary Protas, Valentina Ghisays, Ji Luo, Eric L. DeMarco, Pradeep Thiyyagura, Vivek Devadas, Robert Bauer, Susan M. Landau, Michael Weiner, William J. Jagust, Eric M. Reiman, Kewei Chen
Publikováno v:
Alzheimer's & Dementia. 14