Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Pradeep P. A. Mammen"'
Autor:
Manisha Korb, Allison Peck, Lindsay N. Alfano, Kenneth I. Berger, Meredith K. James, Nupur Ghoshal, Elise Healzer, Claire Henchcliffe, Shaida Khan, Pradeep P. A. Mammen, Sujata Patel, Gerald Pfeffer, Stuart H. Ralston, Bhaskar Roy, William W. Seeley, Andrea Swenson, Tahseen Mozaffar, Conrad Weihl, Virginia Kimonis, the VCP Standards of Care Working Group
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-15 (2022)
Abstract Valosin-containing protein (VCP) associated multisystem proteinopathy (MSP) is a rare inherited disorder that may result in multisystem involvement of varying phenotypes including inclusion body myopathy, Paget’s disease of bone (PDB), fro
Externí odkaz:
https://doaj.org/article/bf65cfbc490c497cb1d7639887c6cbbe
Autor:
Andres Ramirez-Martinez, Yichi Zhang, Kenian Chen, Jiwoong Kim, Bercin K. Cenik, John R. McAnally, Chunyu Cai, John M. Shelton, Jian Huang, Ana Brennan, Bret M. Evers, Pradeep P. A. Mammen, Lin Xu, Rhonda Bassel-Duby, Ning Liu, Eric N. Olson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The nuclear envelope tethers chromatin to the nuclear periphery to control genome architecture. Here, the authors show that Net39 preserves the integrity and gene expression of muscle nuclei in mice, and it may contribute to the pathogenesis of Emery
Externí odkaz:
https://doaj.org/article/3a056dc3d882494d8fb0ecf911b951c9
Autor:
Xuan Jiang, Yanqiu Shao, Faris G. Araj, Alpesh A. Amin, Benjamin M. Greenberg, Mark H. Drazner, Chao Xing, Pradeep P. A. Mammen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 19 (2020)
Background Duchenne muscular dystrophy (DMD) is a neuromuscular disorder caused by mutations within the dystrophin gene. DMD is characterized by progressive skeletal muscle degeneration and atrophy and progressive cardiomyopathy. It has been observed
Externí odkaz:
https://doaj.org/article/8aa8b168092a4349a5297712b3bc66fd
Autor:
Elizabeth M. McNally, Douglas L. Mann, Yigal Pinto, Deepak Bhakta, Gordon Tomaselli, Saman Nazarian, William J. Groh, Takuhisa Tamura, Denis Duboc, Hideki Itoh, Leah Hellerstein, Pradeep P. A. Mammen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 4 (2020)
Abstract Myotonic dystrophy is an inherited systemic disorder affecting skeletal muscle and the heart. Genetic testing for myotonic dystrophy is diagnostic and identifies those at risk for cardiac complications. The 2 major genetic forms of myotonic
Externí odkaz:
https://doaj.org/article/d0d42e502cd741a8a36287c7ec5cd3e7
Autor:
James Keeton, Pedro Engel Gonzalez, Julie Cox, Robert M. Morlend, Alpesh A. Amin, Pradeep P. A. Mammen, Lynn C. Huffman, Faris G. Araj
Publikováno v:
Case Reports in Cardiology, Vol 2020 (2020)
Intracardiac thrombi are associated with an increased morbidity and mortality due to their unpredictability and embolic potential. Right heart thrombus is infrequently encountered in clinical practice outside the scenario of acute pulmonary embolism
Externí odkaz:
https://doaj.org/article/60fa8f3599fd41daad8a2f5d105d0f5b
Publikováno v:
Current Heart Failure Reports. 19:52-62
Autor:
Daniel Cheeran, Shaida Khan, Rohan Khera, Anish Bhatt, Sonia Garg, Justin L. Grodin, Robert Morlend, Faris G. Araj, Alpesh A. Amin, Jennifer T. Thibodeau, Sandeep Das, Mark H. Drazner, Pradeep P. A. Mammen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)
BackgroundDuchenne muscular dystrophy (DMD) is frequently complicated by development of a cardiomyopathy. Despite significant medical advances provided to DMD patients over the past 2 decades, there remains a group of DMD patients who die prematurely
Externí odkaz:
https://doaj.org/article/21f4d3e8381444da81a764e3a8805000
Autor:
Faris G, Araj, Jyoti P, Balani, Alpesh A, Amin, Pradeep P A, Mammen, Sonia, Garg, Michael, Luna
Publikováno v:
The Journal of invasive cardiology. 33(7)
IVC stenosis is a rare complication of bicaval orthotopic heart transplant. IVC stenosis can occur at either the cavo-atrial anastomosis, or the caval cannulation site, with presentations ranging from acute shock early post transplant to a more indol
Autor:
Roel Quintens, Sarvjeet Singh, Katleen Lemaire, Katrien De Bock, Mikaela Granvik, Anica Schraenen, Irene Olga Cornelia Maria Vroegrijk, Veronica Costa, Pieter Van Noten, Dennis Lambrechts, Stefan Lehnert, Leentje Van Lommel, Lieven Thorrez, Geoffroy De Faudeur, Johannes Anthonius Romijn, John Michael Shelton, Luca Scorrano, Henri Roger Lijnen, Peter Jacobus Voshol, Peter Carmeliet, Pradeep Puthenveetil Abraham Mammen, Frans Schuit
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56719 (2013)
Oxidative phosphorylation in mitochondria is responsible for 90% of ATP synthesis in most cells. This essential housekeeping function is mediated by nuclear and mitochondrial genes encoding subunits of complex I to V of the respiratory chain. Althoug
Externí odkaz:
https://doaj.org/article/6e48974138964287b15012c484cb8268
Autor:
Gabriele G, Schiattarella, Francisco, Altamirano, Dan, Tong, Kristin M, French, Elisa, Villalobos, Soo Young, Kim, Xiang, Luo, Nan, Jiang, Herman I, May, Zhao V, Wang, Theodore M, Hill, Pradeep P A, Mammen, Jian, Huang, Dong I, Lee, Virginia S, Hahn, Kavita, Sharma, David A, Kass, Sergio, Lavandero, Thomas G, Gillette, Joseph A, Hill
Publikováno v:
Nature. 568(7752)
Heart failure with preserved ejection fraction (HFpEF) is a common syndrome with high morbidity and mortality for which there are no evidence-based therapies. Here we report that concomitant metabolic and hypertensive stress in mice-elicited by a com