Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Pradeep Nareddy"'
Autor:
Rajesh Singh, Bindi Patel, Rameshwari Rayaji, Sachie Marubayashi, Sean Cho, Stefan Garrido-Shaqfeh, Joseph Kulusich, Cesar Meleza, Nidhi Tibrewal, Joice Thomas, Pradeep Nareddy, Ehesan Sharif, Sharon Zhao, Dave Green, Manmohan Leleti, Jay Powers, Matt Walters, Daniel DiRenzo
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Baoli Li, Steven Gunawan, A. Chan, Sang Y Yun, Pradeep Nareddy, R.R. Davis, Nicholas J. Lawrence, Ernst Schönbrunn, Muhammad Ayaz, Gary W. Reuther, Harshani R. Lawrence
Publikováno v:
J Med Chem
The discovery that aberrant activity of Janus kinase 2 (JAK2) is a driver of myeloproliferative neoplasms (MPNs) has led to significant efforts to develop small molecule inhibitors for this patient population. Ruxolitinib and fedratinib have been app
Autor:
Qun Zhao, Guangchen Li, Pradeep Nareddy, Frank Jordan, Roger Lalancette, Roman Szostak, Michal Szostak
Publikováno v:
Angewandte Chemie (International ed. in English). 61(35)
Amide bond replacement with planar isosteric chalcogen analogues has an important implication for the properties of the N-C(X) linkage in structural chemistry, biochemistry and organic synthesis. Herein, we report the first higher chalcogen derivativ
Autor:
Da Jeong Shim, Elena L. Guevara, Natalia S. Nemeria, Frank Jordan, Junjie Wang, Xu Zhang, Hetal Patel, Jieyu Zhou, Joydeep Chakraborty, Anand Balakrishnan, Pradeep Nareddy, Luying Yang
The Jordan group's interest center on: E. coli (ec) and human (h) pyruvate dehydrogenase (PDHc), 2-oxoglutarate dehydrogenase (OGDHc) and 2-oxoadipate dehydrogenase (OADHc) complexes; and on 1-deoxy-D-xylulose-5-phosphate synthase (DXPS). The most im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc99cf7ec0b8c9c5ed0442a487b4ec76
https://doi.org/10.1016/b978-0-12-409547-2.14833-4
https://doi.org/10.1016/b978-0-12-409547-2.14833-4
Autor:
Pradeep Nareddy, Gary J. Gerfen, Luying Yang, Natalia S. Nemeria, Frank Jordan, Xu Zhang, Michal Szostak
Publikováno v:
Free Radical Biology and Medicine. 115:136-145
Herein are reported unique properties of the novel human thiamin diphosphate (ThDP)-dependent enzyme 2-oxoadipate dehydrogenase (hE1a), known as dehydrogenase E1 and transketolase domain-containing protein 1 that is encoded by the DHTKD1 gene. It is
Autor:
Gary J. Gerfen, Frank Jordan, Elena L. Guevara, Natalia S. Nemeria, Pradeep Nareddy, Michal Szostak
Publikováno v:
Free Radical Biology and Medicine. 108:644-654
Recently, we reported that the human 2-oxoglutarate dehydrogenase (hE1o) component of the 2-oxoglutarate dehydrogenase complex (OGDHc) could produce the reactive oxygen species superoxide and hydrogen peroxide (detected by chemical means) from its su
Publikováno v:
Chemical Science. 8:3204-3210
The ruthenium(II)-catalyzed oxidative cross-coupling of C(sp2)–H bonds with organosilanes has been accomplished for the first time. This novel protocol enlists challenging cyclic and N,N-dialkyl benzamides as weakly-coordinating substrates to achie
Autor:
Frank Jordan, Joydeep Chakraborty, Edgardo T. Farinas, Michal Szostak, Pradeep Nareddy, Natalia S. Nemeria, Xu Zhang
Publikováno v:
AIChE Journal. 66
Autor:
Pradeep Nareddy
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 20:1061-1061
Publikováno v:
Organic letters. 20(2)
The ruthenium(II)-catalyzed, heteroatom-directed C–H arylation of indoles with arylsilanes in water has been developed. The method represents the first example of a ruthenium(II)-catalyzed oxidative C–H arylation in water/aqueous media as a susta