Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Pradeep Manuneedhi Cholan"'
Autor:
Julia Y. Kam, Elinor Hortle, Elizabeth Krogman, Sherridan E. Warner, Kathryn Wright, Kaiming Luo, Tina Cheng, Pradeep Manuneedhi Cholan, Kazu Kikuchi, James A. Triccas, Warwick J. Britton, Matt D. Johansen, Laurent Kremer, Stefan H. Oehlers
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The pathogen Mycobacterium abscessus can switch from a smooth colony form (S) into a highly inflammatory, rough colony form (R) during infection. Here, Kam et al. use an adult zebrafish model of M. abscessus chronic infection to illustrate difference
Externí odkaz:
https://doaj.org/article/21538f5988d2474e8bf1b3bb89145259
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Hyperglycaemia damages the microvasculature in part through the reduced recruitment of immune cells and interference with platelet signalling, leading to poor wound healing and accelerated lipid deposition in mammals. We investigated the uti
Externí odkaz:
https://doaj.org/article/2707e23cd20d44468938a193ff98e615
Autor:
Simone Morris, Kathryn Wright, Vamshikrishna Malyla, Warwick J. Britton, Philip M. Hansbro, Pradeep Manuneedhi Cholan, Stefan H. Oehlers
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 229-236 (2021)
Cigarette smoke (CS)-induced inflammation leads to a range of diseases including chronic obstructive pulmonary disease and cancer. The gut microbiota is a major modifying environmental factor that determine the severity of cigarette smoke-induced pat
Externí odkaz:
https://doaj.org/article/ac3940ada4fb4d368e7289d2319cf3b0
Autor:
Siân P. Cartland, Scott W. Genner, Gonzalo J. Martínez, Stacy Robertson, Maaike Kockx, Ruby CY. Lin, John F. O'Sullivan, Yen Chin Koay, Pradeep Manuneedhi Cholan, Melkam A. Kebede, Andrew J. Murphy, Seth Masters, Martin R. Bennett, Wendy Jessup, Leonard Kritharides, Carolyn Geczy, Sanjay Patel, Mary M. Kavurma
Publikováno v:
iScience, Vol 12, Iss , Pp 41-52 (2019)
Summary: Circulating tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) levels are reduced in patients with cardiovascular disease, and TRAIL gene deletion in mice exacerbates atherosclerosis and inflammation. How TRAIL protects ag
Externí odkaz:
https://doaj.org/article/c7ca2592d76c4f63b979d841c5be347e
Autor:
Belinda A. Di Bartolo, Siân P. Cartland, Scott Genner, Pradeep Manuneedhi Cholan, Melissa Vellozzi, Kerry-Anne Rye, Mary M. Kavurma
Publikováno v:
Journal of Diabetes Research, Vol 2021 (2021)
Background and Aims. Apolipoprotein A-I (ApoA-I), the main component of high-density lipoprotein (HDL), not only promotes reverse cholesterol transport (RCT) in atherosclerosis but also increases insulin secretion in pancreatic β-cells, suggesting t
Externí odkaz:
https://doaj.org/article/2521473870cd41eabc5898d9fbe8ebf0
Autor:
Pradeep Manuneedhi Cholan, Alvin Han, Brad R Woodie, Maxinne Watchon, Angela RM Kurz, Angela S Laird, Warwick J Britton, Lihua Ye, Zachary C Holmes, Jessica R McCann, Lawrence A David, John F Rawls, Stefan H Oehlers
Publikováno v:
Gut Microbes, Vol 12, Iss 1 (2020)
Short-chain fatty acids (SCFAs) are produced by microbial fermentation of dietary fiber in the gut. Butyrate is a particularly important SCFA with anti-inflammatory properties and is generally present at lower levels in inflammatory diseases associat
Externí odkaz:
https://doaj.org/article/2175f10d9d4f41ef94e9d5809bbe0133
Publikováno v:
Antioxidants, Vol 6, Iss 3, p 56 (2017)
Peripheral artery disease (PAD) is caused by narrowing of arteries in the limbs, normally occurring in the lower extremities, with severe cases resulting in amputation of the foot or leg. A potential approach for treatment is to stimulate the formati
Externí odkaz:
https://doaj.org/article/11b7c005585e426984652c03e0df763e
BackgroundAccumulation of lipid in the liver is the first hallmark of both alcohol-related liver disease (ALD) and non-alcohol-related fatty liver disease (NAFLD). Recent studies indicate that specific mutations in lipid genes confer risk and might i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aa292f856836ecd80968b2095cd3e77
https://doi.org/10.1101/2023.04.14.536511
https://doi.org/10.1101/2023.04.14.536511
Autor:
Warwick J. Britton, Jade A. Boland, Geoff McCaughan, Simone Morris, Kaiming Luo, Pradeep Manuneedhi Cholan, Jinbiao Chen, Stefan H. Oehlers
Publikováno v:
BioFactors (Oxford, England)REFERENCES. 48(2)
Gut dysbiosis is an important modifier of pathologies including cardiovascular disease but our understanding of the role of individual microbes is limited. Here, we have used transplantation of mouse microbiota into microbiota-deficient zebrafish lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7c4c6b4cacb71893b720c7e24e9551
https://pubmed.ncbi.nlm.nih.gov/34665899
https://pubmed.ncbi.nlm.nih.gov/34665899
Autor:
Philip M. Hansbro, Pradeep Manuneedhi Cholan, Stefan H. Oehlers, Kathryn Wright, Warwick J. Britton, Simone Morris, Vamshikrishna Malyla
Cigarette smoke (CS)-induced inflammation leads to a range of diseases including chronic obstructive pulmonary disease and cancer. The gut microbiota is a major modifying environmental factor that determine the severity of cigarette smoke-induced pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff68a692f254354eabfb420b0178149e
https://doi.org/10.1101/2021.09.20.461170
https://doi.org/10.1101/2021.09.20.461170