Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Pradeep Kumar Sreenivasaiah"'
Autor:
Shilpa Rani, Pradeep Kumar Sreenivasaiah, Jin Ock Kim, Mi Young Lee, Wan Seok Kang, Yong Sook Kim, Youngkeun Ahn, Woo Jin Park, Chunghee Cho, Do Han Kim
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176071 (2017)
Pressure overload in the heart induces pathological hypertrophy and is associated with cardiac dysfunction. Apoptosis and fibrosis signaling initiated by the endoplasmic reticulum stress (ERS) is known to contribute to these maladaptive effects. The
Externí odkaz:
https://doaj.org/article/c54636adee374f81aaa78abe3cf68930
Publikováno v:
Molecules and Cells
Pathological hypertrophy of the heart is closely associated with endoplasmic reticulum stress (ERS), leading to maladaptations such as myocardial fibrosis, induction of apoptosis, and cardiac dysfunctions. Salubrinal is a known selective inhibitor of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820c1ce00fd788cde8cf8754cf77eeb3
https://doi.org/10.14348/molcells.2017.2259
https://doi.org/10.14348/molcells.2017.2259
Publikováno v:
Molecules and Cells
In the heart, excitation-contraction (E-C) coupling is mediated by Ca(2+) release from sarcoplasmic reticulum (SR) through the interactions of proteins forming the Ca(2+) release unit (CRU). Among them, calsequestrin (CSQ) and histidine-rich Ca(2+) b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e981a709c3856de94231d1f8379a42
https://doi.org/10.14348/molcells.2016.2284
https://doi.org/10.14348/molcells.2016.2284
Publikováno v:
Circulation Research. 107:1185-1197
The endoplasmic reticulum (ER) is a multifunctional intracellular organelle supporting many processes required by virtually every mammalian cell, including cardiomyocytes. It performs diverse functions, including protein synthesis, translocation acro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893cebef8e9eeb97cf5c36d09f8cf682
https://doi.org/10.1161/circresaha.110.227033
https://doi.org/10.1161/circresaha.110.227033
Autor:
Pradeep Kumar Sreenivasaiah, Woo Jin Park, Jin Ock Kim, Wan Seok Kang, Do Han Kim, Shilpa Rani, Chunghee Cho, Mi-Young Lee, Youngkeun Ahn, Yong Sook Kim
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 4, p e0176071 (2017)
PLOS ONE(12): 4
PLoS ONE, Vol 12, Iss 4, p e0176071 (2017)
PLOS ONE(12): 4
Pressure overload in the heart induces pathological hypertrophy and is associated with cardiac dysfunction. Apoptosis and fibrosis signaling initiated by the endoplasmic reticulum stress (ERS) is known to contribute to these maladaptive effects. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d90de99cdf92a8e5323c4a79d13ebb
https://doi.org/10.1371/journal.pone.0176071
https://doi.org/10.1371/journal.pone.0176071
Publikováno v:
Biochemical and biophysical research communications. 421(3)
Evidence has shown that endoplasmic reticulum stress (ERS) is associated with the pathogenesis of cardiac hypertrophy. The aim of this study was to investigate whether direct alleviation of ER stress by 4-phenylbutyric acid (PBA), a known chemical ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510adb803897dc9ae472b2dd48576699
https://pubmed.ncbi.nlm.nih.gov/22525677
https://pubmed.ncbi.nlm.nih.gov/22525677
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 1 (2010)
Frontiers in Physiology, Vol 1 (2010)
Dynamic and rapidly evolving nature of systems driven research imposes special requirements on the technology, approach, design and architecture of computational infrastructure including database and web application. Several solutions have been propo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107cf46066ab3ac58bd67f817cb726ae
Publikováno v:
Nucleic Acids Research
Integrated Pathway Resources, Analysis and Visualization System (iPAVS) is an integrated biological pathway database designed to support pathway discovery in the fields of proteomics, transcriptomics, metabolomics and systems biology. The key goal of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491887b17169b751373aab63dd92fd59
https://doi.org/10.1016/j.bpj.2011.11.997
https://doi.org/10.1016/j.bpj.2011.11.997
Publikováno v:
Biophysical Journal. 96:650a
A major emphasis in systems biology is to unfold the dynamic network properties of complex biological processes through modeling and simulation utilizing various experimental data. CIDMS was developed to provide an integrated bioinformatics platform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b451a78f06e793b7ce08f228a0ceb61
https://doi.org/10.1016/j.bpj.2008.12.3431
https://doi.org/10.1016/j.bpj.2008.12.3431
Autor:
Rani, Shilpa1, Sreenivasaiah, Pradeep Kumar1, Kim, Jin Ock1, Lee, Mi Young1, Kang, Wan Seok2, Kim, Yong Sook2, Ahn, Youngkeun2, Park, Woo Jin1, Cho, Chunghee1, Kim, Do Han1 dhkim@gist.ac.kr
Publikováno v:
PLoS ONE. 4/20/2017, Vol. 12 Issue 4, p1-16. 16p.