Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Pradeep Chopra"'
Autor:
Lin Liu, Pradeep Chopra, Xiuru Li, Kim M. Bouwman, S. Mark Tompkins, Margreet A. Wolfert, Robert P. de Vries, Geert-Jan Boons
Publikováno v:
ACS Central Science, Vol 7, Iss 6, Pp 1009-1018 (2021)
Externí odkaz:
https://doaj.org/article/ef99a56ab01d47058b98ad8209934824
Autor:
Connor H. O’ Meara, Lucy A. Coupland, Farzaneh Kordbacheh, Benjamin J. C. Quah, Chih-Wei Chang, David A. Simon Davis, Anna Bezos, Anna M. Browne, Craig Freeman, Dillon J. Hammill, Pradeep Chopra, Gergely Pipa, Paul D. Madge, Esther Gallant, Courtney Segovis, Angela F. Dulhunty, Leonard F. Arnolda, Imogen Mitchell, Levon M. Khachigian, Ross W. Stephens, Mark von Itzstein, Christopher R. Parish
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Histones, proteins that bind DNA, are toxic for pathogens outside cells but can also cause multi-organ damage as seen in sepsis. Here the authors develop small negatively charged molecules that can be used as histone antidotes, and show that they imp
Externí odkaz:
https://doaj.org/article/47652de3a653433fb4ea511fb90437ea
Autor:
Rebecca L. Miller, Scott E. Guimond, Ralf Schwörer, Olga V. Zubkova, Peter C. Tyler, Yongmei Xu, Jian Liu, Pradeep Chopra, Geert-Jan Boons, Márkó Grabarics, Christian Manz, Johanna Hofmann, Niclas G. Karlsson, Jeremy E. Turnbull, Weston B. Struwe, Kevin Pagel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Heparan sulfates (HS) contain functionally relevant structural motifs, but determining their monosaccharide sequence remains challenging. Here, the authors develop an ion mobility mass spectrometry-based method that allows unambiguous characterizatio
Externí odkaz:
https://doaj.org/article/771c43443fb14659b5131577553e2f14
Autor:
Ditmer T. Talsma, Felix Poppelaars, Wendy Dam, Anita H. Meter-Arkema, Romain R. Vivès, Peter Gál, Geert-Jan Boons, Pradeep Chopra, Annamaria Naggi, Marc A. Seelen, Stephan P. Berger, Mohamed R. Daha, Coen A. Stegeman, Jacob van den Born, the COMBAT Consortium
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
It is well-known that heparin and other glycosaminoglycans (GAGs) inhibit complement activation. It is however not known whether fractionation and/or modification of GAGs might deliver pathway-specific inhibition of the complement system. Therefore,
Externí odkaz:
https://doaj.org/article/ab413b7510b74aa8a261d57227ebb687
Autor:
Estée C. H. Feldman, Daniel P. Hivick, P. Maxwell Slepian, Susan T. Tran, Pradeep Chopra, Rachel Neff Greenley
Publikováno v:
Children, Vol 7, Iss 9, p 146 (2020)
Ehlers–Danlos syndromes (EDS) are a group of connective tissue disorders that manifest with hyperextensibility of joints and skin, and general tissue fragility. While not a major criterion for clinical diagnosis, pain is a frequently endorsed sympt
Externí odkaz:
https://doaj.org/article/3c0e63b2f5694eb8a867a92d5ec62f59
Publikováno v:
Sultan Qaboos University Medical Journal, Vol 11, Iss 3, Pp 403-406 (2011)
Schwannomas are benign, encapsulated and slow-growing nerve sheath tumours arising from Schwann cells. The schwannoma arising from the cervical sympathetic chain (SCSC) is a very rare tumour. It usually presents as a slow growing, painless and asympt
Externí odkaz:
https://doaj.org/article/6d67602d52444dfbac82ecd744302d90
Publikováno v:
Sultan Qaboos University Medical Journal, Vol 9, Iss 2, Pp 162-166 (2009)
Marjolin’s ulcers are malignancies that arise in chronic venous ulcers, scars, burns, long standing wounds or sinuses. Radiography provides important information regarding bone destruction and periosteal reaction, and magnetic resonance (MR) imagin
Externí odkaz:
https://doaj.org/article/e55543a525ba48eeb462a51db627a477
Autor:
Pradeep Chopra
Publikováno v:
Sultan Qaboos University Medical Journal, Vol 10, Iss 2, Pp 276-277 (2010)
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Externí odkaz:
https://doaj.org/article/334ddd734b7e441384f3a01f2937b157
Autor:
Shang-Te Danny Hsu, Gour Chand Daskhan, Linh Nguyen, Stephen M. Tompkins, Geert-Jan Boons, Elena N. Kitova, Todd L. Lowary, Tzu-Jing Yang, Ling Han, Kelli A. McCord, Mohamed Elaish, Duong T Bui, Robert P. de Vries, Ilhan Tomris, John S. Klassen, Kim M. Bouwman, Andrew Mason, Pradeep Chopra, Lori J. West, Lara K. Mahal, Steven Willows, Tom C. Hobman, Dhanraj Kumawat, Matthew S. Macauley
Publikováno v:
Nature Chemical Biology, 18(1), 81. Nature Publishing Group
Emerging evidence suggests that host glycans influence severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Here, we reveal that the receptor-binding domain (RBD) of the spike (S) protein on SARS-CoV-2 recognizes oligosaccharides c
Autor:
Jeremy E. Turnbull, Rebecca L. Miller, Kevin Pagel, Johanna Hofmann, Scott E. Guimond, Jian Liu, Yongmei Xu, Olga V. Zubkova, Márkó Grabarics, Weston B. Struwe, Peter C. Tyler, Christian Manz, Niclas G. Karlsson, Geert-Jan Boons, Pradeep Chopra, Ralf Schwörer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications, 11(1). Nature Publishing Group
Nature communications
Miller, R L, Guimond, S E, Schwörer, R, Zubkova, O V, Tyler, P C, Xu, Y, Liu, J, Chopra, P, Boons, G-J, Grabarics, M, Manz, C, Hofmann, J, Karlsson, N G, Turnbull, J E, Struwe, W B & Pagel, K 2020, ' Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides ', Nature Communications, vol. 11, no. 1, 1481 . https://doi.org/10.1038/s41467-020-15284-y
Nature Communications
Nature Communications, 11(1). Nature Publishing Group
Nature communications
Miller, R L, Guimond, S E, Schwörer, R, Zubkova, O V, Tyler, P C, Xu, Y, Liu, J, Chopra, P, Boons, G-J, Grabarics, M, Manz, C, Hofmann, J, Karlsson, N G, Turnbull, J E, Struwe, W B & Pagel, K 2020, ' Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides ', Nature Communications, vol. 11, no. 1, 1481 . https://doi.org/10.1038/s41467-020-15284-y
Despite evident regulatory roles of heparan sulfate (HS) saccharides in numerous biological processes, definitive information on the bioactive sequences of these polymers is lacking, with only a handful of natural structures sequenced to date. Here,