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pro vyhledávání: '"Pradeep Bista"'
Akademický článek
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Autor:
Christopher Morabito, Chris Stevens, Jou-Ku Chung, Rafif Dagher, Pradeep Bista, Kristine Bernard, Pamela Gustafson, Michele Gunsior, Andy Nichols
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:AB136
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb18f79b443b776f0d794ebd0f1619ed
https://doi.org/10.1016/j.jaci.2022.12.426
https://doi.org/10.1016/j.jaci.2022.12.426
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:AB142
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eac0e57985a72e2542129c426af3b765
https://doi.org/10.1016/j.jaci.2022.12.444
https://doi.org/10.1016/j.jaci.2022.12.444
Publikováno v:
Journal of Allergy and Clinical Immunology. 149:AB167
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80d1f50568d261c135ae410e33e97a5e
https://doi.org/10.1016/j.jaci.2021.12.554
https://doi.org/10.1016/j.jaci.2021.12.554
Autor:
Chi B. Vu, Min Ding, Ericka L. Benson, Robert Kleemann, Martine C. Morrison, Rick B. Vega, Diana Y. Lee, Maisy Yeager, Michael R. Jirousek, Andrew J. Nichols, Guosheng Liang, Teake Kooistra, Michael Zimmer, Jill C. Milne, Dominic Picarella, Peter Y. Wielinga, Feng Liu, Jay D. Horton, Pradeep Bista
Publikováno v:
Hepatology Communications
CAT-2003 is a novel conjugate of eicosapentaenoic acid (EPA) and niacin designed to be hydrolyzed by fatty acid amide hydrolase to release EPA inside cells at the endoplasmic reticulum. In cultured liver cells, CAT-2003 blocked the maturation of ster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1aefafffecf69c7c647ca6b24725e51
http://europepmc.org/articles/PMC5721391
http://europepmc.org/articles/PMC5721391
Autor:
Andrew J. Nichols, John F. Reilly, Mitchell E. Allen, David Brown, Chi B. Vu, Alexander H. Thomson, Diana Lee, Justin B. Perry, Pradeep Bista
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1859:e48-e49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fee3f5db7005feb9c1bd96110ea5abc
https://doi.org/10.1016/j.bbabio.2018.09.146
https://doi.org/10.1016/j.bbabio.2018.09.146
Autor:
Robert H. Scannevin, Kenneth J. Rhodes, Mi Young Jung, Matvey E. Lukashev, Sowmya Chollate, Melanie N. Shackett, Masayuki Yamamoto, Weike Zeng, Sarah Ryan, Hiral Patel, Pradeep Bista
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 341:274-284
Oxidative stress is central to the pathology of several neurodegenerative diseases, including multiple sclerosis, and therapeutics designed to enhance antioxidant potential could have clinical value. The objective of this study was to characterize th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726689985fd6f8b86aa0a8ad08c76553
https://doi.org/10.1124/jpet.111.190132
https://doi.org/10.1124/jpet.111.190132
Autor:
Ralf A. Linker, Robert H. Scannevin, Rebecca Conrad, Matvey E. Lukashev, Sowmya Chollate, Pradeep Bista, Sarah Ryan, Ralf Gold, Gisa Ellrichmann, Alex Buko, Kate Dawson, De-Hyung Lee, Weike Zeng, Susan Goelz, Xiaoping Hronowsky, Wolfgang Brück, Anne M van Dam, Stefan Wiese
Publikováno v:
Linker, R A, Lee, D-H, Ryan, S, van Dam, A M, Conrad, R, Bista, P, Zeng, W, Hronowsky, X, Buko, A, Chollate, S, Ellrichmann, G, Brück, W, Dawson, K, Goelz, S, Wiese, S, Scannevin, R H, Lukashev, M & Gold, R 2011, ' Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway ', Brain, vol. 134, no. Pt 3, pp. 678-692 . https://doi.org/10.1093/brain/awq386
Brain, 134(Pt 3), 678-692. Oxford University Press
Brain, 134(Pt 3), 678-692. Oxford University Press
Inflammation and oxidative stress are thought to promote tissue damage in multiple sclerosis. Thus, novel therapeutics enhancing cellular resistance to free radicals could prove useful for multiple sclerosis treatment. BG00012 is an oral formulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed61aa844041b5c2014c42e141589646
https://hdl.handle.net/1871/46762
https://hdl.handle.net/1871/46762
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Introduction: Triglycerides from chylomicron and VLDL particles are cleared in the periphery through Lipoprotein lipase (LPL). LPL is negatively regulated by Angiopoietin-like proteins 3 and 4 (Angptl3/4) and Apolipoprotein C3 (apoC3). CAT-2003 is an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd22e3e2ef0c056447d7db2c707949c9
https://doi.org/10.1161/atvb.34.suppl_1.237
https://doi.org/10.1161/atvb.34.suppl_1.237
Autor:
Michael Zimmer, Dominic Picarella, Feng Liu, Pradeep Bista, Diana Lee, Chi Vu, Michael Jirousek
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Introduction: CAT-2003 is an orally active small molecule that inhibits SREBP maturation (nSREBP-1 and nSREBP-2) and activation of SREBP-target genes, including PCSK9. CAT-2003 mechanism of action was studied in HepG2 cells and in the transgenic ApoE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78c2dc821c2dc3c7878cc652af4e4bfd
https://doi.org/10.1161/atvb.34.suppl_1.6
https://doi.org/10.1161/atvb.34.suppl_1.6