Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pradeep B. Lasonkar"'
Publikováno v:
Organic Letters. 20:7011-7014
The total synthesis of (±)-quinagolide, which is a D2 receptor agonist, was accomplished via a ceric ammonium nitrate (CAN)-mediated regioselective azidoalkoxylation of enol ether route. Key features of the synthesis include Claisen rearrangement, P
Autor:
Moneerah J. Alqahtani, Ikhlas A. Khan, Amar G. Chittiboyina, Saqlain Haider, Shuneize Slater, Pradeep B. Lasonkar
Publikováno v:
Tetrahedron Letters. 59:807-810
Novel, functionalized octahydrochromene derivatives were synthesized in a single step via the Prins reaction. Enantiomerically pure (+)-isopulegol was reacted with benzaldehyde to stereoselectively yield the corresponding octahydro-2H-chromen-4-ol de
Publikováno v:
Organic letters. 20(22)
The total synthesis of (±)-quinagolide, which is a D
Autor:
Appasaheb L. Kadam, Subhash P. Chavan, Lalit B. Khairnar, Pradeep B. Lasonkar, Prakash N. Chavan
Publikováno v:
Synlett. 25:2879-2882
A synthesis of (±)-biotin is described starting from simple starting materials viz. cyclohexanone and amino malonic acid ester. The key steps involved are MgCl2/Et3N coupling of amino malonic acid ester derivative and acid chloride, Mitsunobu reacti
Publikováno v:
Tetrahedron: Asymmetry. 24:1473-1479
A novel and enantioselective synthesis of d -(+)-biotin has been accomplished starting from commercially available cyclohexanone. The key steps in the sequence are the Sharpless asymmetric dihydroxylation of a ( E )-ethyl 3-(2-chlorocyclohex-1-en-1-y
Autor:
Subhash P. Chavan, Pradeep B. Lasonkar
Publikováno v:
Synthesis. 45:3399-3403
A new alternative route for the synthesis of olopatadine is described. The present strategy involves a Lewis acid mediated ring opening of a cyclic ether to introduce 3-(dimethylamino)propylidene group as the side chain.
Publikováno v:
Toxicology and applied pharmacology. 318
German chamomile is one of the most popular herbal ingredients used in cosmetics and personal care products. Allergic skin reactions following topical application of German chamomile have been occasionally reported, although it is not fully understoo
Publikováno v:
Planta Medica. 82
Autor:
Amar G. Chittiboyina, Bharathi Avula, W Feng, Yan-Hong Wang, Ikhlas A. Khan, Mei Wang, Pradeep B. Lasonkar, Pieter A. Cohen, S Sagi
Publikováno v:
Planta Medica. 82
Publikováno v:
Planta Medica. 82
Mesembrine is a naturally occurring alkaloid which has been isolated from Sceletium tortosum, family Aizoaceae. It has a therapeutic value in the treatment of depression as selective serotonin reuptake inhibitor. Because of its challenging chemical f