Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Prachi Mehrotra"'
Autor:
Alexandre Laliberté, Caterina Prelli Bozzo, Christiane Stahl-Hennig, Victoria Hunszinger, Simone Joas, Ulrike Sauermann, Berit Roshani, Antonina Klippert, Maria Daskalaki, Kerstin Mätz-Rensing, Nicole Stolte-Leeb, Gregory K. Tharp, Dietmar Fuchs, Prachi Mehrotra Gupta, Guido Silvestri, Sydney A. Nelson, Laura Parodi, Luis Giavedoni, Steven E. Bosinger, Konstantin M.J. Sparrer, Frank Kirchhoff
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108351- (2023)
Summary: The accessory viral protein R (Vpr) is encoded by all primate lentiviruses. Vpr counteracts DNA repair pathways, modulates viral immune sensing, and induces cell-cycle arrest in cell culture. However, its impact in vivo is controversial. Her
Externí odkaz:
https://doaj.org/article/d97b01ec79264fde9d35d16bbbf8793a
Autor:
Simone Joas, Ulrike Sauermann, Berit Roshani, Antonina Klippert, Maria Daskalaki, Kerstin Mätz-Rensing, Nicole Stolte-Leeb, Anke Heigele, Gregory K. Tharp, Prachi Mehrotra Gupta, Sydney Nelson, Steven Bosinger, Laura Parodi, Luis Giavedoni, Guido Silvestri, Daniel Sauter, Christiane Stahl-Hennig, Frank Kirchhoff
Publikováno v:
Cell Reports, Vol 30, Iss 7, Pp 2261-2274.e7 (2020)
Summary: The inability of Nef to downmodulate the CD3-T cell receptor (TCR) complex distinguishes HIV-1 from other primate lentiviruses and may contribute to its high virulence. However, the role of this Nef function in virus-mediated immune activati
Externí odkaz:
https://doaj.org/article/03906fd8cd7840c89119e99657af1d0a
Autor:
Laliberté, Alexandre, Prelli Bozzo, Caterina, Stahl-Hennig, Christiane, Hunszinger, Victoria, Joas, Simone, Sauermann, Ulrike, Roshani, Berit, Klippert, Antonina, Daskalaki, Maria, Mätz-Rensing, Kerstin, Stolte-Leeb, Nicole, Tharp, Gregory K., Fuchs, Dietmar, Gupta, Prachi Mehrotra, Silvestri, Guido, Nelson, Sydney A., Parodi, Laura, Giavedoni, Luis, Bosinger, Steven E., Sparrer, Konstantin M.J., Kirchhoff, Frank
Publikováno v:
In iScience 15 December 2023 26(12)
Autor:
Gupta, Prachi Mehrotra, Balle, Christina, Tharp, Gregory K., Nelson, Sydney A., Gasper, Melanie A., Brown, Bryan, Alisoltani, Arghavan, Onono, Maricianah, Palanee-Phillips, Thesla, Nair, Gonsagrie, Ayele, Hosseana, Noel-Romas, Laura, Passmore, Jo-Ann S., Burgener, Adam D., Heffron, Renee, Jaspan, Heather B., Bosinger, Steven E.
Publikováno v:
In Clinical Immunology October 2023 255
Autor:
Joas, Simone, Sauermann, Ulrike, Roshani, Berit, Klippert, Antonina, Daskalaki, Maria, Mätz-Rensing, Kerstin, Stolte-Leeb, Nicole, Heigele, Anke, Tharp, Gregory K., Gupta, Prachi Mehrotra, Nelson, Sydney, Bosinger, Steven, Parodi, Laura, Giavedoni, Luis, Silvestri, Guido, Sauter, Daniel, Stahl-Hennig, Christiane, Kirchhoff, Frank
Publikováno v:
In Cell Reports 18 February 2020 30(7):2261-2274
Akademický článek
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Autor:
Sydney A. Nelson, Kerstin Mätz-Rensing, Christiane Stahl-Hennig, Simone Joas, Anke Heigele, Luis D. Giavedoni, Ulrike Sauermann, Daniel Sauter, Guido Silvestri, Antonina Klippert, Prachi Mehrotra Gupta, Berit Roshani, Frank Kirchhoff, Gregory K. Tharp, Laura M. Parodi, Maria Daskalaki, Steven E. Bosinger, Nicole Stolte-Leeb
Publikováno v:
Cell reports
Cell Reports, Vol 30, Iss 7, Pp 2261-2274.e7 (2020)
Cell Reports, Vol 30, Iss 7, Pp 2261-2274.e7 (2020)
SUMMARY The inability of Nef to downmodulate the CD3-T cell receptor (TCR) complex distinguishes HIV-1 from other primate lentiviruses and may contribute to its high virulence. However, the role of this Nef function in virus-mediated immune activatio
Autor:
Gayatri Ramakrishnan, Gunasekaran Dhandapani, Prachi Mehrotra, Narayanaswamy Srinivasan, Madathiparambil G. Madanan
Publikováno v:
Molecular BioSystems. 13:883-891
Leptospirosis, a potentially life-threatening disease, remains the most widespread zoonosis caused by pathogenic species of Leptospira. The pathogenic spirochaete, Leptospira interrogans, is characterized by its ability to permeate human host tissues
Publikováno v:
Proteins. 86(7)
The overall function of a multi-domain protein is determined by the functional and structural interplay of its constituent domains. Traditional sequence alignment-based methods commonly utilize domain-level information and provide classification only
Autor:
Prachi Mehrotra, Ramachandra M. Bhaskara, Narayanaswamy Srinivasan, Mutharasu Gnanavel, Juliette Martin, Ramaswamy Rakshambikai
Publikováno v:
BMC Bioinformatics
Background: The function of a protein can be deciphered with higher accuracy from its structure than from its amino acid sequence. Due to the huge gap in the available protein sequence and structural space, tools that can generate functionally homoge