Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Prachand Issarapu"'
Autor:
Prachand Issarapu, Manisha Arumalla, Hannah R. Elliott, Suraj S. Nongmaithem, Alagu Sankareswaran, Modupeh Betts, Sara Sajjadi, Noah J. Kessler, Swati Bayyana, Sohail R. Mansuri, Maria Derakhshan, G. V. Krishnaveni, Smeeta Shrestha, Kalyanaraman Kumaran, Chiara Di Gravio, Sirazul A. Sahariah, Eleanor Sanderson, Caroline L. Relton, Kate A. Ward, Sophie E. Moore, Andrew M. Prentice, Karen A. Lillycrop, Caroline H. D. Fall, Matt J. Silver, Giriraj R. Chandak, the EMPHASIS study group
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Human height is strongly influenced by genetics but the contribution of modifiable epigenetic factors is under-explored, particularly in low and middle-income countries (LMIC). We investigate links between blood DNA methylation and child hei
Externí odkaz:
https://doaj.org/article/ea9bc0f20bff47a5b3eb1876f8c6f819
Autor:
Matt J Silver, Ayden Saffari, Noah J Kessler, Gririraj R Chandak, Caroline HD Fall, Prachand Issarapu, Akshay Dedaniya, Modupeh Betts, Sophie E Moore, Michael N Routledge, Zdenko Herceg, Cyrille Cuenin, Maria Derakhshan, Philip T James, David Monk, Andrew M Prentice
Publikováno v:
eLife, Vol 11 (2022)
In humans, DNA methylation marks inherited from gametes are largely erased following fertilisation, prior to construction of the embryonic methylome. Exploiting a natural experiment of seasonal variation including changes in diet and nutritional stat
Externí odkaz:
https://doaj.org/article/3e0df17bd8c3409aa09b5b63f8a77876
Autor:
Giriraj R. Chandak, Matt J. Silver, Ayden Saffari, Karen A. Lillycrop, Smeeta Shrestha, Sirazul Ameen Sahariah, Chiara Di Gravio, Gail Goldberg, Ashutosh Singh Tomar, Modupeh Betts, Sara Sajjadi, Lena Acolatse, Philip James, Prachand Issarapu, Kalyanaraman Kumaran, Ramesh D. Potdar, Andrew M. Prentice, Caroline H. D. Fall, the EMPHASIS study group, Meraj Ahmed, Harsha Chopra, Cyrus Cooper, Momodou K. Darboe, Meera Gandhi, Gail R. Goldberg, Ramatoulie Janha, Landing M. A. Jarjou, Lovejeet Kaur, Sarah H. Kehoe, Mohammed Ngum, Suraj S. Nongmaithem, Stephen Owens, Ann Prentice, Tallapragada Divya Sri Priyanka, Harshad Sane, Kate A. Ward, Dilip Kumar Yadav, Chittaranjan S. Yajnik
Publikováno v:
BMC Nutrition, Vol 3, Iss 1, Pp 1-13 (2017)
Abstract Background Animal studies have shown that nutritional exposures during pregnancy can modify epigenetic marks regulating fetal development and susceptibility to later disease, providing a plausible mechanism to explain the developmental origi
Externí odkaz:
https://doaj.org/article/06959d9aec6347888aa484ba6cdbe163
Autor:
Sara Sajjadi, Dilip K. Yadav, Matt J. Silver, Karen A. Lillycrop, Sirazul A. Sahariah, Philip James, Kalyanaraman Kumaran, Ayden Saffari, Ashutosh Singh Tomar, Modupeh Betts, Giriraj R. Chandak, Caroline H.D. Fall, Prachand Issarapu, Smeeta Shrestha, Andrew M. Prentice, Akshay Dedaniya
Publikováno v:
The American Journal of Clinical Nutrition
Background: Maternal nutrition in pregnancy has been linked to offspring health in early and later life, with changes to DNA methylation (DNAm) proposed as a mediating mechanism. Objective: We investigated intervention-associated DNAm changes in chil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0fc1cfb0d4d1df1471ffa179e242f8
https://doi.org/10.1093/ajcn/nqaa193
https://doi.org/10.1093/ajcn/nqaa193
Autor:
Elie, Antoun, Prachand, Issarapu, Chiara, di Gravio, Smeeta, Shrestha, Modupeh, Betts, Ayden, Saffari, Sirazul A, Sahariah, Alagu, Sankareswaran, Manisha, Arumalla, Andrew M, Prentice, Caroline H D, Fall, Matt J, Silver, Giriraj R, Chandak, Karen A, Lillycrop, Ann, Prentice
Publikováno v:
Clinical Epigenetics
Background The prevalence of cardiometabolic disease (CMD) is rising globally, with environmentally induced epigenetic changes suggested to play a role. Few studies have investigated epigenetic associations with CMD risk factors in children from low-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5f3d0f898bed1c79afbaeb2d739d86
https://doi.org/10.1186/s13148-021-01213-3
https://doi.org/10.1186/s13148-021-01213-3
Autor:
Matt J Silver, Ayden Saffari, Noah J Kessler, Gririraj R Chandak, Caroline HD Fall, Prachand Issarapu, Akshay Dedaniya, Modupeh Betts, Sophie E Moore, Michael N Routledge, Zdenko Herceg, Cyrille Cuenin, Maria Derakhshan, Philip T James, David Monk, Andrew M Prentice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e509c76fda43a454608a39b086e5bb3
https://doi.org/10.7554/elife.72031.sa2
https://doi.org/10.7554/elife.72031.sa2
Autor:
András Szabó, Prachand Issarapu, Emmanuelle Masson, Peter Bugert, Denise Lasher, Sumit Paliwal, Claudia Ruffert, Shin Hamada, K. Radha Mani, Helmut Laumen, Jian-Min Chen, Atsushi Masamune, David A. Groneberg, Katharina Seltsam, Kiyoshi Kume, Xunjun Xiao, Maren Ewers, Eriko Nakano, M. Michael Barmada, Tooru Shimosegawa, Jonas Rosendahl, Giriraj R. Chandak, Thomas Müller, Mark E. Lowe, Miklós Sahin-Tóth, Heiko Witt, Seema Bhaskar, David C. Whitcomb, Claude Férec
Publikováno v:
American Journal of Gastroenterology. 114:974-983
OBJECTIVES. Premature activation of the digestive protease trypsin within the pancreatic parenchyma is a critical factor in the pathogenesis of pancreatitis. Alterations in genes that affect intra-pancreatic trypsin activity are associated with chron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8f489f34cd4a57579c412918eeeab3
https://doi.org/10.14309/ajg.0000000000000051
https://doi.org/10.14309/ajg.0000000000000051
Autor:
Giriraj R, Chandak, Matt J, Silver, Ayden, Saffari, Karen A, Lillycrop, Smeeta, Shrestha, Sirazul Amin, Sahariah, Chiara, Di Gravio, Gail, Goldberg, Ashutosh Singh, Tomar, Modupeh, Betts, Sara, Sajjadi, Lena, Acolatse, Philip, James, Prachand, Issarapu, Kalyanaraman, Kumaran, Ramesh D, Potdar, Andrew M, Prentice, Caroline Hd, Fall
Publikováno v:
BMC nutrition. 3
BACKGROUND: Animal studies have shown that nutritional exposures during pregnancy can modify epigenetic marks regulating fetal development and susceptibility to later disease, providing a plausible mechanism to explain the developmental origins of he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d778e7fe52a1a5ba3ddde17766411a84
https://pubmed.ncbi.nlm.nih.gov/30820326
https://pubmed.ncbi.nlm.nih.gov/30820326
Autor:
Fall Chd, Philip T. James, Prachand Issarapu, Dilip K. Yadav, Smeeta Shrestha, Lovejeet Kaur, Ashutosh Singh Tomar, Sara Sajjadi, Matt J. Silver, Giriraj R. Chandak, Karen A. Lillycrop, Ayden Saffari, Andrew M. Prentice
Publikováno v:
International Journal of Epidemiology
BackgroundMounting evidence suggests that nutritional exposures during pregnancy influence the fetal epigenome, and that these epigenetic changes can persist postnatally, with implications for disease risk across the life course.MethodsWe review huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b6452823f9c9c2d2c806579f07a519f
https://doi.org/10.1093/ije/dyy153
https://doi.org/10.1093/ije/dyy153
Autor:
Giriraj R. Chandak, David Neil Cooper, Emmanuelle Masson, Sumit Paliwal, Emmanuelle Génin, Hao Wu, Claude Férec, Prachand Issarapu, Wen-Bin Zou, Seema Bhaskar, Zhao-Shen Li, Arnaud Boulling, Jian-Min Chen, Zhuan Liao
Publikováno v:
Human Mutation
Human Mutation, Wiley, 2017, 38 (8), pp.1014-1024. ⟨10.1002/humu.23269⟩
Human Mutation, Wiley, 2017, 38 (8), pp.1014-1024. ⟨10.1002/humu.23269⟩
The haplotype harboring the SPINK1 c.101A>G (p.Asn34Ser) variant (also known as rs17107315:T>C) represents the most important heritable risk factor for idiopathic chronic pancreatitis identified to date. The causal variant contained within this risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceccb0ecd8c34e3d6f16d64d48586f2b
https://hal.inrae.fr/hal-02946985
https://hal.inrae.fr/hal-02946985