Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Prabuddha S. Pathinayake"'
Autor:
Surajit Dey, Wenying Lu, Heinrich C. Weber, Collin Chia, Prabuddha S. Pathinayake, Peter A.B. Wark, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research, Vol 10, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/6b30d2c786a040b292e813692a8578fc
Autor:
Surajit Dey, Wenying Lu, Greg Haug, Collin Chia, Josie Larby, Heinrich C. Weber, Archana Vijay Gaikwad, Prem Bhattarai, Affan Mahmood Shahzad, Prabuddha S. Pathinayake, Peter A. B. Wark, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-21 (2023)
Abstract Background Although asthma and chronic obstructive pulmonary disease (COPD) are two distinct chronic airway inflammatory diseases, they often co-exist in a patient and the condition is referred to as asthma-COPD overlap (ACO). Lack of eviden
Externí odkaz:
https://doaj.org/article/5e348fad49dd4876b16753136037991c
Autor:
Nikhil T. Awatade, Andrew T. Reid, Kristy S. Nichol, Kurtis F. Budden, Punnam Chander Veerati, Prabuddha S. Pathinayake, Christopher L. Grainge, Philip M. Hansbro, Peter A. B. Wark
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Primary air liquid interface (ALI) cultures of bronchial epithelial cells are used extensively to model airway responses. A recent advance is the development of conditional reprogramming that enhances proliferative capability. Several differ
Externí odkaz:
https://doaj.org/article/34e398b88c08484c9891f298e967ba74
Autor:
Louisa L. Y. Chan, Danielle E. Anderson, Hong Sheng Cheng, Fransiskus Xaverius Ivan, Si Chen, Adrian E. Z. Kang, Randy Foo, Akshamal M. Gamage, Pei Yee Tiew, Mariko Siyue Koh, Ken Cheah Hooi Lee, Kristy Nichol, Prabuddha S. Pathinayake, Yik Lung Chan, Tsin Wen Yeo, Brian G. Oliver, Peter A. B. Wark, Linbo Liu, Nguan Soon Tan, Lin-Fa Wang, Sanjay H. Chotirmall
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory respiratory disease characterized by airflow limitation and infective exacerbations. Here, Chan et al. report the generation of nasopharyngeal and bronchial COPD organoids derived
Externí odkaz:
https://doaj.org/article/ede2ba3eb3ee4bc2bdcf003223f85869
Publikováno v:
Viruses, Vol 15, Iss 2, p 402 (2023)
Type 2 immune responses are characterized by elevated type 2 cytokines and blood eosinophilia. Emerging evidence suggests that people with chronic type 2 inflammatory lung diseases are not particularly susceptible to SARS-CoV-2 infection. Intriguingl
Externí odkaz:
https://doaj.org/article/c06bd17fd4ba4d5a891e863f7f5ee603
Autor:
Aran Singanayagam, Nicholas Glanville, Jason L. Girkin, Yee Man Ching, Andrea Marcellini, James D. Porter, Marie Toussaint, Ross P. Walton, Lydia J. Finney, Julia Aniscenko, Jie Zhu, Maria-Belen Trujillo-Torralbo, Maria Adelaide Calderazzo, Chris Grainge, Su-Ling Loo, Punnam Chander Veerati, Prabuddha S. Pathinayake, Kristy S. Nichol, Andrew T. Reid, Phillip L. James, Roberto Solari, Peter A. B. Wark, Darryl A. Knight, Miriam F. Moffatt, William O. Cookson, Michael R. Edwards, Patrick Mallia, Nathan W. Bartlett, Sebastian L. Johnston
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Corticosteroid therapy is frequently used for chronic obstructive pulmonary disease (COPD) but its use is associated with increased risk of pneumonia. Here the authors show that corticosteroid use impairs innate and adaptive immunity to rhinovirus in
Externí odkaz:
https://doaj.org/article/8d63530adb10416897e7c8b0db9afbdb
Autor:
David W. Waters, Michael Schuliga, Prabuddha S. Pathinayake, Lan Wei, Hui-Ying Tan, Kaj E. C. Blokland, Jade Jaffar, Glen P. Westall, Janette K. Burgess, Cecilia M. Prêle, Steven E. Mutsaers, Christopher L. Grainge, Darryl A. Knight
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1162 (2021)
Idiopathic pulmonary fibrosis (IPF) is a chronic disease characterised by a dense fibrosing of the lung parenchyma. An association between IPF and cellular senescence is well established and several studies now describe a higher abundance of senescen
Externí odkaz:
https://doaj.org/article/9b887b3e6a684a2cbaf59851201b3ebd
Publikováno v:
Viruses, Vol 7, Iss 12, Pp 6613-6630 (2015)
Enterovirus 71 (EV71) is a major infectious disease affecting millions of people worldwide and it is the main etiological agent for outbreaks of hand foot and mouth disease (HFMD). Infection is often associated with severe gastroenterological, pulmon
Externí odkaz:
https://doaj.org/article/754ad9ae3c8e4f7f890b33269db0e082
Autor:
Prabuddha S. Pathinayake, Alan C.-Y. Hsu, David W. Waters, Philip M. Hansbro, Lisa G. Wood, Peter A. B. Wark
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Asthma is a heterogeneous, chronic inflammatory disease of the airways. It is a complex disease with different clinical phenotypes and results in a substantial socioeconomic burden globally. Poor understanding of pathogenic mechanisms of the disease
Externí odkaz:
https://doaj.org/article/f186a5f15c4d4be1a806aa5b6f13b614
Autor:
Nikhil T Awatade, Andrew T Reid, Kristy S Nichol, Kurtis F Budden, Punnam Chander Veerati, Prabuddha S Pathinayake, Christopher L Grainge, Philip M Hansbro, Peter AB Wark
Introduction: Primary air liquid interface (ALI) cultures of bronchial epithelial cells are used extensively to model airway responses. A recent advance is the development of conditional reprogramming that enhances proliferative capability. Several d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::192d26bfb5f6cbca80f86e499d61003c
https://doi.org/10.21203/rs.3.rs-2914728/v1
https://doi.org/10.21203/rs.3.rs-2914728/v1