TRAPEZE: a randomised controlled trial of the clinical effectiveness and cost-effectiveness of chemotherapy with zoledronic acid, strontium-89, or both, in men with bony metastatic castration-refractory prostate cancer

Autor: Nicholas James, Sarah Pirrie, Ann Pope, Darren Barton, Lazaros Andronis, Ilias Goranitis, Stuart Collins, Duncan McLaren, Joe O’Sullivan, Chris Parker, Emilio Porfiri, John Staffurth, Andrew Stanley, James Wylie, Sharon Beesley, Alison Birtle, Janet Brown, Prabir Chakraborti, Martin Russell, Lucinda Billingham

Publikováno v: Health Technology Assessment, Vol 20, Iss 53 (2016)

Background: Bony metastatic castration-refractory prostate cancer is associated with a poor prognosis and high morbidity. TRAPEZE was a two-by-two factorial randomised controlled trial of zoledronic acid (ZA) and strontium-89 (Sr-89), each combined w

Externí odkaz: https://doaj.org/article/c615d29188e14af3b091335974572196

Temporary treatment cessation versus continuation of first-line tyrosine kinase inhibitor in patients with advanced clear cell renal cell carcinoma (STAR): an open-label, non-inferiority, randomised, controlled, phase 2/3 trial

Autor: Janet E Brown, Kara-Louise Royle, Walter Gregory, Christy Ralph, Anthony Maraveyas, Omar Din, Timothy Eisen, Paul Nathan, Tom Powles, Richard Griffiths, Robert Jones, Naveen Vasudev, Matthew Wheater, Abdel Hamid, Tom Waddell, Rhona McMenemin, Poulam Patel, James Larkin, Guy Faust, Adam Martin, Jayne Swain, Janine Bestall, Christopher McCabe, David Meads, Vicky Goh, Tze Min Wah, Julia Brown, Jenny Hewison, Peter Selby, Fiona Collinson, Judith Carser, Gopalakrishnan Srinivasan, Fiona Thistlewaite, Ashraf Azzabi, Mark Beresford, David Farrugia, Marios Decatris, Carys Thomas, Joanna Gale, James McAleer, Alison Clayton, Ekaterini Boleti, Thomas Geldart, Santhanam Sundar, Jason Lester, Nachi Palaniappan, Mohan Hingorani, Khaliq Rehman, Mohammad Khan, Naveed Sarwar, Janine Graham, Alastair Thomson, Narayanan Srihari, Denise Sheehan, Rajaguru Srinivasan, Omar Khan, Andrew Stockdale Jane Worlding, Stergios Boussios, Nicholas Stuart, Carey MacDonald-Smith, Falalu Danwata, Duncan McLaren, Aravindhan Sundaramurthy, Anna Lydon, Sharon Beesley, Kathryn Lees, Mohini Varughese, Emma Gray, Angela Scott, Mark Baxter, Anna Mullard, Pasquale Innominato, Gaurav Kapur, Anil Kumar, Natalie Charnley, Caroline Manetta, Prabir Chakraborti, Prantik Das, Sarah Rudman, Henry Taylor, Christos Mikropoulos, Martin Highley, Dakshinamoorthy Muthukumar, Anjali Zarkar, Roy Vergis, Seshadri Sriprasad, Patryk Brulinski, Amanda Clarke, Richard Osbourne, Melanie Harvey, Renata Dega, Geoffrey Sparrow, Urmila Barthakur, Erica Beaumont, Agnieszka Michael, Emilio Porfiri, Faisal Azam, Ravi Kodavtiganti

Publikováno v: STAR Investigators, Brown, J E, Royle, K-L, Gregory, W, Ralph, C, Maraveyas, A, Din, O, Eisen, T, Nathan, P, Powles, T, Griffiths, R, Jones, R, Vasudev, N, Wheater, M, Hamid, A, Waddell, T, McMenemin, R, Patel, P, Larkin, J, Faust, G, Martin, A, Swain, J, Bestall, J, McCabe, C, Meads, D, Goh, V, Min Wah, T, Brown, J, Hewison, J, Selby, P & Collinson, F 2023, ' Temporary treatment cessation versus continuation of first-line tyrosine kinase inhibitor in patients with advanced clear cell renal cell carcinoma (STAR): an open-label, non-inferiority, randomised, controlled, phase 2/3 trial ', Lancet Oncology, vol. 24, no. 3, pp. 213-227 . https://doi.org/10.1016/S1470-2045(22)00793-8

Temporary drug treatment cessation might alleviate toxicity without substantially compromising efficacy in patients with cancer. We aimed to determine if a tyrosine kinase inhibitor drug-free interval strategy was non-inferior to a conventional conti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a633cdaf72543d0ca87f46d23005d79
https://doi.org/10.1016/s1470-2045(22)00793-8

Modification in Physiological Performances of French Bean (Phaseolus vulgaris L.) Seed Through Seed Priming

Autor: Bingiala Laloo, Prabir Chakraborti

Publikováno v: Indian Journal Of Agricultural Research.

Background: The three priming modes using various organic and inorganic compounds for hydro-priming, osmo-priming (PEG 6000, CaCl2, KNO3) and halo-priming (thiourea, GA3) with control were considered, to study the improvement in physiological perform

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44e84169282ea1006803a809d1aa14ed
https://doi.org/10.18805/ijare.a-6001

Use of Seed Priming to Improve the Physiological Performances in Oat (Avena sativa L.) Seed

Autor: Prabir Chakraborti, Desetty J.M.S.N.K. Sri Veda

Publikováno v: International Journal of Current Microbiology and Applied Sciences. 9:1006-1016

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9c68f18bb32286b72e478ccb5acaf43
https://doi.org/10.20546/ijcmas.2020.909.125

Application of priming through organic compounds in oat (Avena sativa L.) seed production

Autor: Desetty J.M.S.N.K. Sri Veda, Prabir Chakraborti

Publikováno v: International Journal of Chemical Studies. 8:2549-2553

To acquire potentiality under productivity and seed quality in Oat crop, the seed priming was applied through implication of three organic compounds viz. Naphthalene acetic acid (NAA), Salicylic acid (SA) and Nicotinic acid (NA) under diverse concent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::35f854026e3f94b2eb2d3a42b6c337a2
https://doi.org/10.22271/chemi.2020.v8.i2am.9131