Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Prabhjit K Grewal"'
Autor:
Fumin Fu, Michael Pietropaolo, Lei Cui, Shilpa Pandit, Weiyan Li, Oleg Tarnavski, Suraj S Shetty, Jing Liu, Jennifer M Lussier, Yutaka Murakami, Prabhjit K Grewal, Galina Deyneko, Gordon M Turner, Andrew K P Taggart, M Gerard Waters, Shaun Coughlin, Yuichiro Adachi
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0256512 (2022)
The mouse is a useful preclinical species for evaluating disease etiology due to the availability of a wide variety of genetically modified strains and the ability to perform disease-modifying manipulations. In order to establish an atrial filtration
Externí odkaz:
https://doaj.org/article/9e4a05b9d5094a40b0cf21268159371c
Autor:
Nissi Varki, Ricardo D. Lardone, Victor Nizet, Peter V. Aziz, Gabriel R. Rubio, Prabhjit K. Grewal, Dzung T. Le, Satoshi Uchiyama, Jamey D. Marth
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The endocytic Ashwell-Morell receptor (AMR) of hepatocytes detects pathogen remodeling of host glycoproteins by neuraminidase in the bloodstream and mitigates the lethal coagulopathy of sepsis. We have investigated the mechanism of host protection by
Autor:
Rachael J. Ritchie, Prabhjit K. Grewal, Gareth Cross, Samantha J. L. Knight, Martin Bobrow, Mark C. Hirst, Kay E. Davies
Three fragile sites, FRAXA, FRAXE and FRAXF lie in the Xq27-28 region of the human X chromosome. The expression of FRAXA is associated with the fragile X syndrome, the most prevalent form of inherited mental retardation whilst the expression of FRAXE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24997ee72e187c1b595420062d9942bb
https://doi.org/10.1093/hmg/3.12.2115
https://doi.org/10.1093/hmg/3.12.2115
Autor:
Jamey D. Marth, Prabhjit K. Grewal
Publikováno v:
Nature Reviews Immunology. 8:874-887
This Review discusses how the diversity of glycan structures that are produced in the secretory pathway and are displayed at the cell surface and in extracellular compartments can have both homeostatic and pathogenic effects on the development and fu
Autor:
Mark Boton, Kevin E. Draves, Prabhjit K. Grewal, Edward A. Clark, Lorna Santos, Jamey D. Marth
Publikováno v:
The Journal of Immunology. 180:4561-4569
Recent studies have shown that dendritic cells (DCs) regulate B cell functions. In this study, we report that bone marrow (BM)-derived immature DCs, but not mature DCs, can inhibit BCR-induced proliferation of B cells in a contact-dependent manner. T
Autor:
Prabhjit K. Grewal, Ryan S. Green, Kazuaki Ohtsubo, Brian E. Collins, Mark Boton, Kevin Ramirez, Akira Saito, Daniel Chui, Jamey D. Marth
Publikováno v:
Molecular and Cellular Biology. 26:4970-4981
The ST6Gal-I sialyltransferase produces Siglec ligands for the B-cell-specific CD22 lectin and sustains humoral immune responses. Using multiple experimental approaches to elucidate the mechanisms involved, we report that ST6Gal-I deficiency induces
Autor:
Prabhjit K. Grewal, Jane E. Hewitt
Publikováno v:
Human Molecular Genetics. 12:R259-R264
Recently, post-translational modification of proteins has been defined as a new area of focus for muscular dystrophy research by the identification of a group of disease genes that encode known or putative glycosylation enzymes. Walker-Warburg Syndro
Autor:
Prabhjit K. Grewal, Jane E. Hewitt
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1573:216-224
The myodystrophy (myd) mutation arose spontaneously and has an autosomal recessive mode of inheritance. Homozygous mutant mice display a severe, progressive muscular dystrophy. Using a positional cloning approach, we identified the causative mutation
Publikováno v:
Nature Genetics. 28:151-154
Spontaneous and engineered mouse mutants have facilitated our understanding of the pathogenesis of muscular dystrophy and they provide models for the development of therapeutic approaches. The mouse myodystrophy (myd) mutation produces an autosomal r
Autor:
Anne-Marie Jones, Mark Maconochie, Richard J.L.F. Lemmers, Jane E. Hewitt, Prabhjit K. Grewal, Rune R. Frants
Publikováno v:
Gene. 240:389-398
We report the cloning of a cDNA for the mouse unconventional myosin Myo9b , the orthologue of the rat myr5 and human MYOIXb genes. A full-length spleen cDNA of 7087 bp encoding a protein of 1961 amino acids was isolated. By RT–PCR, we show that Myo