Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Prabhat K. Sehgal"'
SV40 Infection Associated With Rituximab Treatment After Kidney Transplantation in Nonhuman Primates
Autor:
Keisuke Minamimura, Anthony P. Monaco, Isaac E. Stillman, Norihiko Ogawa, Prabhat K. Sehgal, Takashi Maki, Amanda K. Marr-Belvin, Susan V. Westmoreland, Kanetoshi Sato, Tetsuro Kodaka, Akira Kanamoto, Angela Carville, Rita Gottschalk
Publikováno v:
Transplantation. 85:893-902
Background. A regimen consisting of polyclonal anti-T-cell antibody, sirolimus (SRL), and donor bone marrow (DBM) infusion induces robust transplantation tolerance to skin allografts in mice. We investigated the effect of a similar regimen in a nonhu
Autor:
Prabhat K. Sehgal, Dan Huang, Liyou Qiu, Ling Shen, George Du, Norman L. Letvin, Zheng W. Chen, Yun Shen
Publikováno v:
Journal of Virology. 78:14023-14032
The immune mechanisms associated with the evolution from latent to clinically active mycobacterial coinfection in human immunodeficiency virus type 1 (HIV-1)-infected humans remain poorly understood. Previous work has demonstrated that macaques infec
Autor:
Prabhat K. Sehgal, Margaret R. Lentz, Eliezer Masliah, Susan V. Westmoreland, Eva M. Ratai, Kenneth Earl Sakaie, Andrew A. Lackner, Julian He, Jane B. Greco, R. Gilberto Gonzalez
Publikováno v:
Magnetic Resonance in Medicine. 51:1108-1114
The metabolic response of the rhesus macaque brain during acute simian immunodeficiency virus (SIV) infection was investigated with in vivo 1H MR spectroscopy. Fifteen rhesus macaques were studied before inoculation, and once or twice after infection
Autor:
Dejiang Zhou, Yun Shen, George Z. Du, Meredith A. Simon, Dan Huang, Liyou Qiu, Norman L. Letvin, Ling Shen, Qifan Wang, Zheng W. Chen, Prabhat K. Sehgal, Xiaomin Lai
Publikováno v:
Journal of Virology. 77:2998-3006
Adaptive immune responses of γδ T cells during active mycobacterial coinfection of human immunodeficiency virus-infected humans have not been studied. Macaques infected with the simian immunodeficiency virus (SIV) SIVmac were employed to determine
Autor:
Ling Shen, Liyou Qiu, Xioamin Lai, Craig T. Morita, Xuejun Zeng, Zhongchen Kou, Yunyaun Li, Michael B. Brenner, Michelle Clagett, Dejiang Zhou, Yun Shen, Meredith A. Simon, Norman L. Letvin, Liming Jiang, Zheng W. Chen, Robert E. Hunt, Jim Estep, Prabhat K. Sehgal, Qifan Wang
Publikováno v:
Science. 295:2255-2258
To examine the role of T cell receptor (TCR) in γδ T cells in adaptive immunity, a macaque model was used to follow Vγ2Vδ2+T cell responses to mycobacterial infections. These phosphoantigen-specific γδ T cells displayed major expansion duringMy
Autor:
Prabhat K. Sehgal, Zheng W. Chen, Xuejun Zeng, Yunyuan Li, Meredith A. Simon, Xioamin Lai, Dejiang Zhou, Yun Shen, Ling Shen, Norman L. Letvin, Laura V. Chalifoux
Publikováno v:
Infection and Immunity. 70:869-877
The mechanism by which human immunodeficiency virus (HIV)-Mycobacterium tuberculosiscoinfection facilitates development of HIV-related tuberculosis is poorly characterized. Macaque models of simian immunodeficiency virus (SIVmac)-Mycobacterium bovisB
Autor:
Meredith A. Simon, Zheng W. Chen, David Lee-Parritz, Ling Shen, Zhongchen Kou, Dejiang Zhou, Yun Shen, Norman L. Letvin, Prabhat K. Sehgal
Publikováno v:
Journal of Virology. 75:4713-4720
While it is well established that cellular activation can increase human immunodeficiency virus (HIV) replication in T lymphocytes, it is also clear that both activated CD8+and CD4+T lymphocytes mediate anti-HIV activity. To assess the relative impor
Autor:
Ronald S. Veazey, Daniel E. Shvetz, Irene C. Tham, Amy E. Forand, Andrew A. Lackner, Prabhat K. Sehgal, Keith G. Mansfield, Laura V. Chalifoux, MaryAnn DeMaria
Publikováno v:
Journal of Virology. 74:57-64
It has recently been shown that rapid and profound CD4+T-cell depletion occurs almost exclusively within the intestinal tract of simian immunodeficiency virus (SIV)-infected macaques within days of infection. Here we demonstrate (by three- and four-c
Autor:
Dejiang Zhou, Yun Shen, Laura Chalifoux, David Lee-Parritz, Meredith Simon, Prabhat K. Sehgal, Leiya Zheng, Matilda Halloran, Zheng W. Chen
Publikováno v:
The Journal of Immunology. 162:2204-2216
It has recently been proposed that Mycobacterium tuberculosis may enhance the pathogenicity of HIV infections and accelerate the course of HIV disease. This hypothesis has been tested in the present study using a simian immunodeficiency virus of maca