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pro vyhledávání: '"Prabhakara Rao Tharra"'
Publikováno v:
The Journal of Organic Chemistry. 86:11845-11861
We report synthesis of two diastereomeric structures previously proposed for the complex secondary metabolite pseurotin A(2). Both structures were accessed from the same building blocks taking advantage of a stereodivergent nickel(II)-iamine-catalyze
Autor:
Matěj Sklenář, Svitlana Skoroplyas, Radek Fedr, Lukáš Kubala, Ondřej Vašíček, Jakub Švenda, David Chalupa, Prabhakara Rao Tharra
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 69
Background The frequency of allergic diseases is constantly rising. Dysregulated production of isotype E immunoglobulins is one of the key factors behind allergic reactions and its modulation is therefore an important target for pharmacological inter