Zobrazeno 1 - 10
of 404
pro vyhledávání: '"Prabhakara R"'
Autor:
Babunageswararao Kanuri, Gopalkrishna Sreejit, Priosmita Biswas, Andrew J. Murphy, Prabhakara R. Nagareddy
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110274- (2024)
Summary: Given the extensive participation of myeloid cells (especially monocytes and macrophages) in both inflammation and resolution phases post-myocardial infarction (MI) owing to their biphasic role, these cells are considered as crucial players
Externí odkaz:
https://doaj.org/article/8d4c618f5bd244fca38512ddba8d3dfa
Autor:
C. Alicia Traughber, Kara Timinski, Ashutosh Prince, Nilam Bhandari, Kalash Neupane, Mariam R. Khan, Esther Opoku, Emmanuel Opoku, Gregory Brubaker, Junchul Shin, Junyoung Hong, Babunageswararao Kanuri, Elif G. Ertugral, Prabhakara R. Nagareddy, Chandrasekhar R. Kothapalli, Olga Cherepanova, Jonathan D. Smith, Kailash Gulshan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 8 (2024)
Background Pyroptosis executor GsdmD (gasdermin D) promotes atherosclerosis in mice and humans. Disulfiram was recently shown to potently inhibit GsdmD, but the in vivo efficacy and mechanism of disulfiram's antiatherosclerotic activity is yet to be
Externí odkaz:
https://doaj.org/article/15b7d8b60152495897f66b350118e328
Autor:
Paolina Crocco, Denise Vecchie, Sreejit Gopalkrishna, Serena Dato, Giuseppe Passarino, Martin E. Young, Prabhakara R. Nagareddy, Giuseppina Rose, Maria De Luca
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Syndecan-4 (SDC4) is a member of the heparan sulfate proteoglycan family of cell-surface receptors. We and others previously reported that variation in the SDC4 gene was associated with several components of the metabolic syndrome
Externí odkaz:
https://doaj.org/article/14585715ebe64a638960b7f9dae2c252
Autor:
Douglas R. Moellering, Kelley Smith-Johnston, Christian Kelley, Melissa J. Sammy, Jason Benedict, Guy Brock, Jillian Johnson, Kedryn K. Baskin, Wael N. Jarjour, Martha A. Belury, Peter J. Reiser, Prabhakara R. Nagareddy, Beatriz Y. Hanaoka
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-14 (2023)
Abstract Background Insulin resistance affects a substantial proportion of patients with rheumatoid arthritis (RA). Skeletal muscle mitochondrial dysfunction results in the accumulation of lipid intermediates that interfere with insulin signaling. We
Externí odkaz:
https://doaj.org/article/9fb94adc1c0b4699a29dab1d74a767ad
Autor:
Naresh Kumar, Matthew J Pestrak, Qian Wu, Omar Santiagonunez Ahumada, Sheri Dellos-Nolan, Noushin Saljoughian, Rajni Kant Shukla, Cortney F Mitchem, Prabhakara R Nagareddy, Latha P Ganesan, Lafuse P William, Daniel J Wozniak, Murugesan V S Rajaram
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011573 (2023)
Pseudomonas aeruginosa (P.a.) infection accounts for nearly 20% of all cases of hospital acquired pneumonia with mortality rates >30%. P.a. infection induces a robust inflammatory response, which ideally enhances bacterial clearance. Unfortunately, e
Externí odkaz:
https://doaj.org/article/52fbcfa4bf47448c99082917222fe255
Autor:
Nanako Kawaguchi, Antonino Bruno, Prabhakara R. Nagareddy, Toshio Nakanishi, Murugesan V. S. Rajaram, Gaia Spinetti
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/89f6c1a1ba844897a90238d743d83767
Autor:
Dragana Dragoljevic, Man Kit Sam Lee, Gerard Pernes, Pooranee K Morgan, Cynthia Louis, Waled Shihata, Kevin Huynh, Arina A Kochetkova, Patrick W Bell, Natalie A Mellett, Peter J Meikle, Graeme I Lancaster, Michael J Kraakman, Prabhakara R Nagareddy, Beatriz Y Hanaoka, Ian P Wicks, Andrew J Murphy
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 4, Pp n/a-n/a (2023)
Abstract Objectives The leading cause of mortality in patients with rheumatoid arthritis is atherosclerotic cardiovascular disease (CVD). We have shown that murine arthritis impairs atherosclerotic lesion regression, because of cellular cholesterol e
Externí odkaz:
https://doaj.org/article/48c0e47238314555b62510482001ecff
Autor:
Paolina Crocco, Denise Vecchie, Sreejit Gopalkrishna, Serena Dato, Giuseppe Passarino, Martin E. Young, Prabhakara R. Nagareddy, Giuseppina Rose, Maria De Luca
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/d2ce19f41cce4aca990ad51a49f91545
Autor:
Albert Dahdah, Jillian Johnson, Sreejit Gopalkrishna, Robert M. Jaggers, Darren Webb, Andrew J. Murphy, Nordin M. J. Hanssen, Beatriz Y. Hanaoka, Prabhakara R. Nagareddy
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The body’s inflammatory response involves a series of processes that are necessary for the immune system to mitigate threats from invading pathogens. Leukocyte migration is a crucial process in both homeostatic and inflammatory states. The mechanis
Externí odkaz:
https://doaj.org/article/e26894bfcf9742c38e24a1a5e8b660f4
Autor:
Albert Dahdah, Robert M. Jaggers, Gopalkrishna Sreejit, Jillian Johnson, Babunageswararao Kanuri, Andrew J. Murphy, Prabhakara R. Nagareddy
Publikováno v:
Cells, Vol 11, Iss 20, p 3190 (2022)
Smoking is one of the most prominent addictions of the modern world, and one of the leading preventable causes of death worldwide. Although the number of tobacco smokers is believed to be at a historic low, electronic cigarette use has been on a dram
Externí odkaz:
https://doaj.org/article/17a2cdd0c63843c89eb4aafabac460d7