Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Prabhakara P. Reddi"'
Autor:
Emily G. Kaye, Kavyashree Basavaraju, Geoffrey M. Nelson, Helena D. Zomer, Debarun Roy, Irene Infancy Joseph, Reza Rajabi-Toustani, Huanyu Qiao, Karen Adelman, Prabhakara P. Reddi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Male germ cell development requires precise regulation of gene activity in a cell-type and stage-specific manner, with perturbations in gene expression during spermatogenesis associated with infertility. Here, we use steady-state, nascent an
Externí odkaz:
https://doaj.org/article/dde5609169b7435cbf7f1eda489eb40f
Autor:
Emily G. Kaye, Geoffrey M. Nelson, Helena D. Zomer, Debarun Roy, Irene Infancy Joseph, Karen Adelman, Prabhakara P. Reddi
Male germ cell development requires precise regulation of gene activity in a cell-type and stage-specific manner, with perturbations in gene expression during spermatogenesis associated with infertility. Here, we use steady-state, nascent and single-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::671de899a22eed40556c674ccba70b09
https://doi.org/10.1101/2023.05.08.539879
https://doi.org/10.1101/2023.05.08.539879
Autor:
Helena D, Zomer, Hari Prasad, Osuru, Apoorv, Chebolu, Jeremy M, Rayl, Madeline, Timken, Prabhakara P, Reddi
Publikováno v:
Biology of Reproduction.
TAR DNA binding protein of 43 kD (TDP-43) is an evolutionarily conserved, ubiquitously expressed transcription factor and RNA-binding protein with major human health relevance. TDP-43 is present in Sertoli and germ cells of the testis and is aberrant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23ca754d97f10e2898f54d363ab4c60
https://doi.org/10.1093/biolre/ioac165
https://doi.org/10.1093/biolre/ioac165
Autor:
Anamaria Cruz, Rex A. Hess, Karen F. Doty, Igor F. Canisso, Derek B. Sullivan, Prabhakara P. Reddi
Publikováno v:
Theriogenology
The acrosome plays a critical role in sperm-oocyte interactions during fertilization. SP-10 is an acrosomal matrix protein, which is evolutionarily conserved among mammals. The SP-10 antibody has been shown to be useful for staging the seminiferous c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4424bf4e7a43718446a182ffbe2124
https://doi.org/10.1016/j.theriogenology.2020.06.046
https://doi.org/10.1016/j.theriogenology.2020.06.046
Publikováno v:
Molecular Reproduction and Development. 87:871-879
Sertoli cells play a key role in spermatogenesis by supporting the germ cells throughout differentiation. The isolation of Sertoli cells is essential to study their functions. However, the close contact of Sertoli cells with other testicular cell typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08410416e13796fb8c53b1aafc012e85
https://doi.org/10.1002/mrd.23406
https://doi.org/10.1002/mrd.23406
Publikováno v:
Biochim Biophys Acta Mol Basis Dis
Spinal muscular atrophy (SMA) is one of the major genetic disorders associated with infant mortality. More than 90% of cases of SMA result from deletions of or mutations in the Survival Motor Neuron 1 (SMN1) gene. SMN2, a nearly identical copy of SMN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efcb1684b345d2607e6cfecc5890e12
https://pubmed.ncbi.nlm.nih.gov/33412266
https://pubmed.ncbi.nlm.nih.gov/33412266
Autor:
Prabhakara P. Reddi, Helen P. Cathro, La Toya Ann Roker, Mayuresh M. Abhyankar, Eric Swanson, Hari Prasad Osuru, Patcharin Pramoonjago
Publikováno v:
Molecular Reproduction and Development. 84:675-685
TDP-43 (TAR DNA-binding protein of 43 kDa) is an evolutionarily conserved, ubiquitously expressed, multi-functional DNA/RNA-binding protein with roles in gene transcription, mRNA splicing, stability, transport, micro RNA biogenesis, and suppression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9938d9cec3971d9734b884bbbb274fa1
https://doi.org/10.1002/mrd.22851
https://doi.org/10.1002/mrd.22851
Autor:
Vikram Saini, Shreemanta K. Parida, Jagdish C. Gupta, Somesh Gupta, Hemanta Kumar Kar, Gursaran P. Talwar, Abu Salim Mustafa, Kiran Katoch, Niyaz Ahmed, Prabhakara P. Reddi
Publikováno v:
Biologics : Targets & Therapy
This article reviews briefly the making of an immunoprophylactic-cum-immunotherapeutic vaccine against leprosy. The vaccine is based on cultivable, heat-killed atypical mycobacteria, whose gene sequence is now known. It has been named Mycobacterium i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49df7a98da474982c0bd0a3959c8a41
http://europepmc.org/articles/PMC5422320
http://europepmc.org/articles/PMC5422320
Autor:
Prabhakara P. Reddi
Publikováno v:
Semin Reprod Med
TDP-43 (TAR DNA binding Protein of 43 kD) is a transcription factor and RNA-binding protein with diverse functions. We cloned TDP-43 from the mouse testis in a screen for promoter-binding proteins and showed that it functions as a transcriptional rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe601451f4d9fef4be32fe9d44b6d572
https://doi.org/10.1055/s-0037-1599088
https://doi.org/10.1055/s-0037-1599088
Publikováno v:
Mol Reprod Dev
Sertoli cells play a vital role in spermatogenesis by offering physical and nutritional support to the differentiating male germ cells. They form the blood-testis barrier and secrete growth factors essential for germ cell differentiation. Sertoli cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83218b56f10b7b44844e9a38f658a116
https://pubmed.ncbi.nlm.nih.gov/32743879
https://pubmed.ncbi.nlm.nih.gov/32743879