Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Prabha Dias"'
Autor:
Cristina V. Iancu, Ariane Briegel, William F. Tivol, Elizabeth R. Wright, Zhiheng Yu, Lu Gan, D. Prabha Dias, Grant J. Jensen, Jordan B Schooler, Zhuo Li, Gregory P. Henderson, Gavin E. Murphy, Yongning He
Publikováno v:
Nature Protocols. 1:2813-2819
Electron cryotomography is the highest-resolution structural technique currently available that can be applied to unique objects such as flexible large protein complexes, irregular viruses, organelles and small cells. Specimens are preserved in a nea
Autor:
Yi YAO, Charles R. TOTH, Lan HUANG, Mei-Lie WONG, Prabha DIAS, Alma L. BURLINGAME, Philip COFFINO, Ching C. WANG
Publikováno v:
Biochemical Journal. 344:349-358
The proteasomes have a central role in catalysing protein degradation among both prokaryotes and eukaryotes. The 20 S proteasome constitutes their catalytic core. In studying the structure of Trypanosoma brucei 20 S proteasomes, we isolated by two-di
Autor:
D. Prabha Dias, Ronald A. Milligan
Publikováno v:
Journal of Molecular Biology. 287:287-292
We have used back-projection methods to obtain three-dimensional maps of motor-protein decorated nine and ten protofilament microtubules polymerized in the presence of high salt and preserved in vitreous ice. The resulting three-dimensional maps show
Autor:
Elena P. Sablin, Ronald A. Milligan, Robert J. Fletterick, Hernando Sosa, D. Prabha Dias, Elizabeth M. Wilson-Kubalek, Andreas Hoenger, Ronald D. Vale, Michael Whittaker
Publikováno v:
Cell. 90:217-224
Kinesin motors convert chemical energy from ATP hydrolysis into unidirectional movement. To understand how kinesin motors bind to and move along microtubules, we fit the atomic structure of the motor domain of Ncd (a kinesin motor involved in meiosis
Autor:
H. Jane Ding, D. Prabha Dias, Ariane Briegel, Rasmus B. Jensen, Grant J. Jensen, Zhuo Li, Zemer Gitai, John Werner
One often compares cells to computers, and signalling proteins to transistors. Location and wiring of those molecular transistors is paramount in defining the function of the subcellular chips. The bacterial chemotactic sensing apparatus is a large,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29cf78148b227d7e2cff1c41e52874e2
https://resolver.caltech.edu/CaltechAUTHORS:20110803-163826561
https://resolver.caltech.edu/CaltechAUTHORS:20110803-163826561
Autor:
H. Jane Ding, D. Prabha Dias, Anthony Martino, Cristina V. Iancu, Dylan M. Morris, Grant J. Jensen, Arlene D. Gonzales
Carboxysomes are organelle-like polyhedral bodies found in cyanobacteria and many chemoautotrophic bacteria that are thought to facilitate carbon fixation. Carboxysomes are bounded by a proteinaceous outer shell and filled with ribulose 1,5-bisphosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7153442f6c0932de5ddc226c2583ec8
https://resolver.caltech.edu/CaltechAUTHORS:20110803-151551421
https://resolver.caltech.edu/CaltechAUTHORS:20110803-151551421
Autor:
Ariane Briegel, Grant J. Jensen, Achilleas S. Frangakis, Zhuo Li, Rasmus B. Jensen, D. Prabha Dias
While the absence of any cytoskeleton was once recognized as a distinguishing feature of prokaryotes, it is now clear that a number of different bacterial proteins do form filaments in vivo. Despite the critical roles these proteins play in cell shap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98538c07217cc4762295d0bd566b694
https://resolver.caltech.edu/CaltechAUTHORS:20110217-125744917
https://resolver.caltech.edu/CaltechAUTHORS:20110217-125744917
Autor:
William F. Tivol, D. Prabha Dias, Jordan Benjamin, Grant J. Jensen, Cristina V. Iancu, Elizabeth R. Wright, J. Bernard Heymann, Gavin E. Murphy
Publikováno v:
Microscopy and Microanalysis. 11
A new 300kV, FEG, helium-cooled, energy-filtered "G2 Polara" electron cryoTEM was recently installed at Caltech. Using this instrument, we have now extensively tested the potential advantages of liquid helium cooling and the inclusion of two orthogon
Autor:
Gavin E. Murphy, Robert C. Morrison, Jordan Benjamin, Elizabeth R. Wright, William F. Tivol, D. Prabha Dias, J. Bernard Heymann, Cristina V. Iancu, Grant J. Jensen
Publikováno v:
Journal of structural biology. 151(3)
Electron cryotomography can be used to solve the three-dimensional structures of individual large macromolecules, assemblies, and even small intact cells to medium (approximately 4-8 nm) resolution in a near-native state, but restrictions in the rang
The thrombin receptor in human platelets is coupled to a GTP binding protein of the G alpha q family
Autor:
Laura Cole, Fabrice Roegiers, Mary Lynn Benka, Prabha Dias, Aaron Granger, Michael E. Mendelsohn, Bob Grant, Guang-rong Wang, William B. Busa, Manisha Raje, Oana Marcu, Anda Burlacu, Matt Lee, Adrian Salic, Jennifer Waters, Amanda Hayward-Lester, Sheree Rybak, Judith Yanowitz, Karen Yeow, Jennifer Smith-Hall, Andre Nussenzweig, Sher Karki, Peter Piepenhagen, Ana DePina, Naoyuki Yamamoto, ShaAvhree Buckman, Suzanne Mann
Publikováno v:
FEBS letters. 363(1-2)
The thrombin receptor is a G protein-coupled receptor, but the G proteins functionally coupled to this receptor in human platelets are not yet definitively identified. Thrombin stimulation of platelets leads to phospholipase C-mediated increases in i