Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Prabesh Gyawali"'
Autor:
Golam Mustafa, Prabesh Gyawali, Jacob A. Taylor, Parastoo Maleki, Marlon V. Nunez, Michael C. Guntrum, Sajad Shiekh, Hamza Balci
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
We present a collection of single molecule work on the i-motif structure formed by the human telomeric sequence. Even though it was largely ignored in earlier years of its discovery due to its modest stability and requirement for low pH levels (pH <
Externí odkaz:
https://doaj.org/article/94eadbf84d5a4a29b63043a4b843ed49
Autor:
Prabesh Gyawali, Rony Saha, Sineth G. Kodikara, Ruipeng Li, Masafumi Fukuto, James T. Gleeson, Gregory P. Smith, Noel A. Clark, Antal Jakli, Hamza Balci, Samuel Sprunt
Publikováno v:
Physical Review Research, Vol 4, Iss 3, p 033046 (2022)
The occurrence of a smectic-B (Sm-B) phase is demonstrated in concentrated aqueous solutions of “gapped” DNA constructs consisting of fully paired duplexes bridged by a flexible, unpaired strand of nucleotides. The Sm-B phase, identified by small
Externí odkaz:
https://doaj.org/article/e15103cecb784c189cc7f9f510736218
Publikováno v:
Molecules, Vol 24, Iss 8, p 1570 (2019)
We performed single molecule studies to investigate the impact of several prominent small molecules (the oxazole telomestatin derivative L2H2-6OTD, pyridostatin, and Phen-DC3) on intermolecular G-quadruplex (i-GQ) formation between two guanine-rich D
Externí odkaz:
https://doaj.org/article/324cdde8ec674efcab628f910c0cb786
Autor:
Sineth G. Kodikara, Prabesh Gyawali, James T. Gleeson, Antal Jakli, Samuel Sprunt, Hamza Balci
Positionally ordered bilayer liquid crystalline nanostructures formed by gapped DNA (GDNA) constructs provide a practical window into DNA-DNA interactions at physiologically relevant DNA concentrations; concentrations several orders of magnitude grea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a946b344535c2e7accf15e69490dc1
https://doi.org/10.1101/2023.01.25.525591
https://doi.org/10.1101/2023.01.25.525591
Autor:
Sajad Shiekh, Amanda Jack, Ayush Saurabh, Golam Mustafa, Sineth G Kodikara, Prabesh Gyawali, Mohammed Enamul Hoque, Steve Pressé, Ahmet Yildiz, Hamza Balci
Publikováno v:
Nucleic acids research. 50(22)
Telomeres terminate with a 50–300 bases long single-stranded G-rich overhang, which can be misrecognized as a DNA damage repair site. Shelterin plays critical roles in maintaining and protecting telomere ends by regulating access of various physiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681f1d095763222386c91848aaa7e590
https://pubmed.ncbi.nlm.nih.gov/36511858
https://pubmed.ncbi.nlm.nih.gov/36511858
Publikováno v:
ChemBioChem. 21:1885-1892
Ribosomes are ribonucleoprotein particles that are essential for protein biosynthesis in all forms of life. During ribosome biogenesis, transcription, folding, modification, and processing of rRNA are coupled to the assembly of proteins. Various asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274b6ec6ca49db857f6e14d6bac0358c
https://doi.org/10.1002/cbic.201900708
https://doi.org/10.1002/cbic.201900708
Autor:
Sajad Shiekh, Amanda Jack, Golam Mustafa, Sineth G. Kodikara, Prabesh Gyawali, Mohammed Enamul Hoque, Ahmet Yildiz, Hamza Balci
Publikováno v:
Biophysical Journal. 122:73a
Shelterin plays critical roles in maintaining and protecting telomeres by regulating access of various physiological agents to telomeric DNA. We present single molecule measurements investigating the impact of the POT1 and a four-component shelterin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabc9ab41852f6fac8e1e483eba1dfe6
https://doi.org/10.1016/j.bpj.2022.11.601
https://doi.org/10.1016/j.bpj.2022.11.601
Autor:
Golam Mustafa, Prabesh Gyawali, Jacob A. Taylor, Parastoo Maleki, Marlon V. Nunez, Michael C. Guntrum, Hamza Balci
We present a collection of single molecule work on the i-motif structure formed by the human telomeric sequence. Even though it was largely ignored in earlier years of its discovery due to its modest stability and requirement for physiologically low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28518139d34dcc47d09d08951ec70439
https://doi.org/10.1101/2021.12.17.473157
https://doi.org/10.1101/2021.12.17.473157
Autor:
James T. Gleeson, Oleg D. Lavrentovich, Mojtaba Rajabi, Greta Babakhanova, Samuel Sprunt, Rony Saha, Zeinab Parsouzi, Christopher J. Welch, Georg H. Mehl, Prabesh Gyawali, Antal Jakli
Publikováno v:
Materials Horizons. 6:1905-1912
Odd–even effects, oscillations in properties of materials comprised of an odd or even number of connected repeating units, are well-known phenomena in materials science. In organic materials, they are usually associated with the number of methylene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bf9df98902a086158b6d656d51af0c1
https://doi.org/10.1039/c9mh00428a
https://doi.org/10.1039/c9mh00428a
Autor:
Mojtaba Rajabi, Prabesh Gyawali, Christopher J. Welch, Oleg D. Lavrentovich, Zeinab Parsouzi, Rony Saha, Samuel Sprunt, Antal Jakli, A. R. Baldwin, Georg H. Mehl, Greta Babakhanova, Taras Turiv, J. T. Gleeson, Hao Wang
Publikováno v:
Physical Chemistry Chemical Physics. 21:13078-13089
We report dynamic light scattering measurements of the orientational (Frank) elastic constants and associated viscosities among a homologous series of a liquid crystalline dimer, trimer, and tetramer exhibiting a uniaxial nematic (N) to twist-bend ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecdfc036e4f2b3838d838dede3c06638
https://doi.org/10.1039/c9cp00984a
https://doi.org/10.1039/c9cp00984a