Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Prabal Giri"'
Autor:
Gopinatha Suresh Kumar, Joydeep Mukherjee, Madhumita Mandal, Churala Pal, Sutapa Roy, Parasuraman Jaisankar, Prabal Giri
Publikováno v:
Journal of Molecular Structure. 1036:1-6
The supramolecular interaction of 3,3′-diindolylmethane (DIM) and its derivatives with α-, β-, and γ-cyclodextrins (CDs) has been investigated to improve their aqueous solubility. A series of complexes of α-, β-, and γ-CDs with DIMs were prep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::084e5bc9624f2993356d3d21fbee20bb
https://doi.org/10.1016/j.molstruc.2012.09.036
https://doi.org/10.1016/j.molstruc.2012.09.036
Autor:
Gopinatha Suresh Kumar, Prabal Giri
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 10:568-577
After fifty years of DNA targeting through intercalators and groove binders and related studies now the current focus is in RNA targeting. Polyadenylic acid [poly(A)] tail of mRNA has been recently established as a potential drug target due to its si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e31f57f98905888d7c1281f2d4a504
https://doi.org/10.2174/138955710791384009
https://doi.org/10.2174/138955710791384009
Autor:
Prabal Giri, Gopinatha Suresh Kumar
Publikováno v:
Mol. BioSyst.. 6:81-88
The use of small molecules to specifically control important cellular functions through binding to nucleic acids is an area of major current interest at the interface of chemical biology and medicinal chemistry. The polyadenylic acid [poly(A)] tail o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a610ee8af3db967c9f202effb30d919
https://doi.org/10.1039/b910706a
https://doi.org/10.1039/b910706a
Autor:
Gopinatha Suresh Kumar, Prabal Giri
Publikováno v:
Current Medicinal Chemistry. 16:965-987
The use of small molecules to specifically control important cellular functions is an area of major current interest at the interface of chemical biology and medicinal chemistry. Recognition of ribonucleic acids (RNA) has emerged more recently as a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6245ef1943ee20e926a5037059b1ad37
https://doi.org/10.2174/092986709787581932
https://doi.org/10.2174/092986709787581932
Autor:
Gopinatha Suresh Kumar, Prabal Giri
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 194:111-121
The interaction of the phototoxic and cytotoxic DNA binding plant alkaloid sanguinarine with double stranded polyadenylic acid has been investigated from multifaceted spectroscopic and calorimetric techniques. The hypochromic and bathochromic shifts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa30fe5ed77ffa9ffbfb0d2a3e526e8a
https://doi.org/10.1016/j.jphotochem.2007.07.022
https://doi.org/10.1016/j.jphotochem.2007.07.022
Autor:
Prabal Giri, Churala Pal
Publikováno v:
Modern Chemistry & Applications.
The thermal behaviour of food strongly depends on its composition. The goals of food processing are to inactivate spoilage and pathogenic microorganisms and to maintain this status in storage. Using calorimetric techniques, many physicochemical effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::869d5fdb822cfd084f926d103ba6e4bd
https://doi.org/10.4172/2329-6798.1000142
https://doi.org/10.4172/2329-6798.1000142
Publikováno v:
DNA and cell biology. 27(2)
There is compelling evidence that cellular DNA is the target of many anticancer agents. Consequently, elucidation of the molecular nature governing the interaction of small molecules to DNA is paramount to the progression of rational drug design stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626d18191b3a2090e771a31995495744
https://pubmed.ncbi.nlm.nih.gov/17924822
https://pubmed.ncbi.nlm.nih.gov/17924822
Publikováno v:
International journal of biological macromolecules. 39(4-5)
The interaction of the protoberberine alkaloid palmatine with single and double stranded structures of poly(A) was studied by various biophysical techniques. Comparative binding studies were also performed with double stranded DNA, t-RNA, poly(C).pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5ed706d72a13c5effe56a75aa511bd
https://pubmed.ncbi.nlm.nih.gov/16678250
https://pubmed.ncbi.nlm.nih.gov/16678250
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(9)
The cytotoxic plant alkaloid palmatine was found to bind strongly by partial intercalation to single stranded poly(A) structure with binding affinity ( K a ) of (8.36 ± 0.26) × 10 5 M −1 . The binding of palmatine was characterized to be exotherm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f2595a82e1d780180df023468d61ac
https://pubmed.ncbi.nlm.nih.gov/16497501
https://pubmed.ncbi.nlm.nih.gov/16497501
Autor:
Ram Chandra Yadav, Motilal Maiti, Prabal Giri, Kakali Bhadra, Rangana Sinha, Gopinatha Suresh Kumar, Sumana Pal
Publikováno v:
Bioorganicmedicinal chemistry. 13(1)
The interaction of berberine with single stranded poly(rA) structure was investigated using a combination of spectrophotometric, spectrofluorimetric, circular dichroic, viscometric, and thermodynamic studies. The interaction process was characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18270107d722c072284a1bac66a71e18
https://pubmed.ncbi.nlm.nih.gov/15582461
https://pubmed.ncbi.nlm.nih.gov/15582461