Anti-beta2 glycoprotein I antibodies cause inflammation and recruit dendritic cells in platelet clearance

Autor: Bondanza A, Aa, Manfredi, Vs, Zimmermann, Matteo Iannacone, Tincani A, Balestrieri G, Mg, Sabbadini, Pr, Querini

Publikováno v: Europe PubMed Central

Scavenger phagocytes are mostly responsible for the in vivo clearance of activated or senescent platelets. In contrast to other particulate substrates, the phagocytosis of platelets does not incite proinflammatory responses in vivo. This study assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::aa7c37d9f98d3b295b8d7239ac6d1b8b
http://europepmc.org/abstract/med/11816715

Use of defibrotide in COVID-19 pneumonia: comparison of a phase II study and a matched real-world cohort control.

Autor: Ruggeri A; Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan., Corrado F; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan; Department of Oncology and Hematology, IRCCS Humanitas Research Hospital, Milan., Voza A; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan; Emergency Department, IRCCS Humanitas Research Hospital, Milan., Wei LJ; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts., Catalano G; Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan., Liberatore C; Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan., Nitti R; Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan., Fedeli C; Emergency Department, IRCCS Humanitas Research Hospital, Milan., Bruno A; Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan., Calabretta E; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan; Department of Oncology and Hematology, IRCCS Humanitas Research Hospital, Milan., Giglio F; Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan., Sciutti F; Emergency Department, IRCCS San Matteo, Pavia Italy., Lunghi F; Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan., Landoni G; Anesthesia and Intensive Care Department. IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Milan., Aghemo A; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan; Division of Internal Medicine and Hepatology, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Milan., Iacobelli M; Life Sciences, Techitra Srl, Milan., Querini PR; Division of Internal Medicine and Hepatology, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Milan, Italy; Department of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan., Richardson PG; Dana-Farber/Brigham and Women's Cancer Center and Harvard Medical School, Boston, Massachusetts., Assanelli A; Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan., Peccatori J; Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan., Ciceri F; Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; Division of Internal Medicine and Hepatology, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Milan., Carlo-Stella C; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan; Department of Oncology and Hematology, IRCCS Humanitas Research Hospital, Milan. carmelo.carlostella@hunimed.eu.

Publikováno v: Haematologica [Haematologica] 2024 Oct 01; Vol. 109 (10), pp. 3261-3268. Date of Electronic Publication: 2024 Oct 01.

Monoclonal antibodies against SARS-CoV-2 to prevent COVID-19 worsening in a large multicenter cohort.

Autor: Soria A; Clinic of Infectious Diseases, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Graziano F; Biostatistics and Clinical Epidemiology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.; Bicocca Bioinformatics, Biostatistics and Bioimaging Centre (B4), School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Ghilardi G; Clinic of Infectious Diseases, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.; School of Medicine, University of Milano-Bicocca, Monza, Italy., Lapadula G; Clinic of Infectious Diseases, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.; School of Medicine, University of Milano-Bicocca, Monza, Italy., Gasperina DD; Department of Medicine and Technological Innovation, University of Insubria, ASST Sette Laghi, Varese, Italy., Benatti SV; Unit of Infectious Diseases, ASST Papa Giovanni XXIII, Bergamo, Italy.; Clinic of Infectious Diseases, ASST Santi Paolo e Carlo, Milan, Italy., Quiros-Roldan E; Clinic of Infectious Diseases, University of Brescia, Brescia, Italy., Milesi M; Unit of Infectious Diseases, ASST Cremona, Cremona, Italy., Bai F; Clinic of Infectious Diseases, ASST Santi Paolo e Carlo, Milan, Italy.; Department of Health Sciences, University of Milan, Milan, Italy., Merli M; Clinic of Infectious Diseases, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Minisci D; Clinic of Infectious Diseases, University of Brescia, Brescia, Italy.; Unit of Infectious Diseases, ASST Mantova, Mantova, Italy., Franzetti M; Unit of Infectious Diseases, ASST Ovest Milano, Legnano, Italy., Asperges E; Clinic of Infectious Diseases, University of Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Chiabrando F; Università Vita-Salute San Raffaele, Milan, Italy., Pocaterra D; IRCCS Humanitas Research Hospital, Rozzano, Italy., Pandolfo A; Unit of Infectious Diseases, ASST Lecco, Italy., Zanini F; ASST Nord Milano, Cinisello Balsamo, Italy., Lombardi D; Unit of Infectious Diseases, ASST Lariana, Como, Italy., Cappelletti A; Clinic of Infectious Diseases, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Rugova A; Clinic of Infectious Diseases, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Borghesi ML; Clinic of Infectious Diseases, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Squillace N; Clinic of Infectious Diseases, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Pusterla L; Unit of Infectious Diseases, ASST Lariana, Como, Italy., Piconi S; Unit of Infectious Diseases, ASST Lecco, Italy., Morelli P; IRCCS Humanitas Research Hospital, Rozzano, Italy., Querini PR; Università Vita-Salute San Raffaele, Milan, Italy.; IRCCS Ospedale San Raffaele, Milan, Italy., Bruno R; Clinic of Infectious Diseases, University of Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Rusconi S; Unit of Infectious Diseases, ASST Ovest Milano, Legnano, Italy.; University of Milano, Milan, Italy., Casari S; Unit of Infectious Diseases, ASST Mantova, Mantova, Italy., Bandera A; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy., Franzetti F; Unit of Infectious Diseases, ASST Valle Olona, Busto Arsizio, Italy., Travi G; Clinic of Infectious Diseases, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., D'Arminio Monforte A; Clinic of Infectious Diseases, ASST Santi Paolo e Carlo, Milan, Italy.; Department of Health Sciences, University of Milan, Milan, Italy., Marchetti G; Clinic of Infectious Diseases, ASST Santi Paolo e Carlo, Milan, Italy.; Department of Health Sciences, University of Milan, Milan, Italy., Pan A; Unit of Infectious Diseases, ASST Cremona, Cremona, Italy., Castelli F; Clinic of Infectious Diseases, University of Brescia, Brescia, Italy., Rizzi M; Unit of Infectious Diseases, ASST Papa Giovanni XXIII, Bergamo, Italy., Dentali F; Department of Medicine and Technological Innovation, University of Insubria, ASST Sette Laghi, Varese, Italy., Mallardo M; Bicocca Bioinformatics, Biostatistics and Bioimaging Centre (B4), School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Rossi E; Bicocca Bioinformatics, Biostatistics and Bioimaging Centre (B4), School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Valsecchi MG; Biostatistics and Clinical Epidemiology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.; Bicocca Bioinformatics, Biostatistics and Bioimaging Centre (B4), School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Galimberti S; Biostatistics and Clinical Epidemiology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.; Bicocca Bioinformatics, Biostatistics and Bioimaging Centre (B4), School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Bonfanti P; Clinic of Infectious Diseases, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.; School of Medicine, University of Milano-Bicocca, Monza, Italy.

Publikováno v: Heliyon [Heliyon] 2024 Aug 13; Vol. 10 (16), pp. e36102. Date of Electronic Publication: 2024 Aug 13 (Print Publication: 2024).

Biomarkers of aging in frailty and age-associated disorders: State of the art and future perspective.

Autor: Salvioli S; Department of Medical and Surgical Science, University of Bologna, Bologna, Italy; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. Electronic address: stefano.salvioli@unibo.it., Basile MS; IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy., Bencivenga L; Department of Translational Medical Sciences, University of Naples Federico II, Napoli, Italy., Carrino S; Department of Medical and Surgical Science, University of Bologna, Bologna, Italy., Conte M; Department of Medical and Surgical Science, University of Bologna, Bologna, Italy., Damanti S; IRCCS Ospedale San Raffaele and Vita-Salute San Raffaele University, Milano, Italy., De Lorenzo R; IRCCS Ospedale San Raffaele and Vita-Salute San Raffaele University, Milano, Italy., Fiorenzato E; Parkinson's Disease and Movement Disorders Unit, Center for Rare Neurological Diseases (ERN-RND), Department of Neurosciences, University of Padova, Padova, Italy., Gialluisi A; Department of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli, Italy; EPIMED Research Center, Department of Medicine and Surgery, University of Insubria, Varese, Italy., Ingannato A; Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy., Antonini A; Parkinson's Disease and Movement Disorders Unit, Center for Rare Neurological Diseases (ERN-RND), Department of Neurosciences, University of Padova, Padova, Italy; Center for Neurodegenerative Disease Research (CESNE), Department of Neurosciences, University of Padova, Padova, Italy., Baldini N; IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy., Capri M; Department of Medical and Surgical Science, University of Bologna, Bologna, Italy., Cenci S; IRCCS Ospedale San Raffaele and Vita-Salute San Raffaele University, Milano, Italy., Iacoviello L; Department of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli, Italy; EPIMED Research Center, Department of Medicine and Surgery, University of Insubria, Varese, Italy., Nacmias B; Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy., Olivieri F; Department of Clinical and Molecular Sciences, Università Politecnica Delle Marche, Ancona, Italy; Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy., Rengo G; Department of Translational Medical Sciences, University of Naples Federico II, Napoli, Italy; Istituti Clinici Scientifici Maugeri IRCCS, Scientific Institute of Telese Terme, Telese Terme, Italy., Querini PR; IRCCS Ospedale San Raffaele and Vita-Salute San Raffaele University, Milano, Italy., Lattanzio F; Scientific Direction, IRCCS INRCA, Ancona, Italy.

Publikováno v: Ageing research reviews [Ageing Res Rev] 2023 Nov; Vol. 91, pp. 102044. Date of Electronic Publication: 2023 Aug 28.

Lower levels of glutathione in the anterior cingulate cortex associate with depressive symptoms and white matter hyperintensities in COVID-19 survivors.

Autor: Poletti S; Vita-Salute San Raffaele University, Milano, Italy; Psychiatry & Clinical Psychobiology, Division of Neuroscience, Scientific Institute IRCCS Ospedale San Raffaele, Milano. Electronic address: poletti.sara@hsr.it., Paolini M; Vita-Salute San Raffaele University, Milano, Italy; Psychiatry & Clinical Psychobiology, Division of Neuroscience, Scientific Institute IRCCS Ospedale San Raffaele, Milano., Mazza MG; Vita-Salute San Raffaele University, Milano, Italy; Psychiatry & Clinical Psychobiology, Division of Neuroscience, Scientific Institute IRCCS Ospedale San Raffaele, Milano., Palladini M; Vita-Salute San Raffaele University, Milano, Italy; Psychiatry & Clinical Psychobiology, Division of Neuroscience, Scientific Institute IRCCS Ospedale San Raffaele, Milano., Furlan R; Vita-Salute San Raffaele University, Milano, Italy; Psychiatry & Clinical Psychobiology, Division of Neuroscience, Scientific Institute IRCCS Ospedale San Raffaele, Milano., Querini PR; Vita-Salute San Raffaele University, Milano, Italy; Psychiatry & Clinical Psychobiology, Division of Neuroscience, Scientific Institute IRCCS Ospedale San Raffaele, Milano., Benedetti F; Vita-Salute San Raffaele University, Milano, Italy; Psychiatry & Clinical Psychobiology, Division of Neuroscience, Scientific Institute IRCCS Ospedale San Raffaele, Milano.

Publikováno v: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology [Eur Neuropsychopharmacol] 2022 Aug; Vol. 61, pp. 71-77. Date of Electronic Publication: 2022 Jun 29.