Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Ppard"'
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35289- (2024)
Genetic susceptibility is an important pathogenic mechanism in diabetic kidney disease (DKD). Our previous studies have identified that PPARδ and GLP-1R are located in a pathway that is closely related to DKD. We aimed to explore the impacts of vari
Externí odkaz:
https://doaj.org/article/66b68f05458a415f98da974fea0573ac
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-12 (2024)
Abstract There are more than 170 subtypes of sarcomas (SARC), which pose a challenge for diagnosis and patient management. Relatively simple or complex karyotypes play an indispensable role in the early diagnosis and effective treatment of SARC. The
Externí odkaz:
https://doaj.org/article/1fe32d85c57348718bd601045ff0914f
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundRelationships of the polymorphisms in fat mass and obesity-associated gene (FTO) and peroxisome proliferator-activated receptor delta gene (PPARD) with metabolic-related diseases remain to be clarified.MethodsOne thousand three hundred and
Externí odkaz:
https://doaj.org/article/e30682aad6db47468660b2bcde9fbca1
Akademický článek
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Autor:
Sandra A. Reza-López, Susana González-Gurrola, Oscar O. Morales-Morales, Janette G. Moreno-González, Ana M. Rivas-Gómez, Everardo González-Rodríguez, Verónica Moreno-Brito, Angel Licón-Trillo, Irene Leal-Berumen
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1791 (2023)
Glucose and lipid metabolism regulation by the peroxisome proliferator-activated receptors (PPARs) has been extensively reported. However, the role of their polymorphisms remains unclear. Objective: To determine the relation between PPAR-γ2 rs180128
Externí odkaz:
https://doaj.org/article/9aaf898bbbaa4b98b642f767c2df8a19
Autor:
Ewelina Maculewicz, Andrzej Mastalerz, Agnieszka Maciejewska-Skrendo, Paweł Cięszczyk, Anna Cywińska, Anna Borecka, Aleksandra Garbacz, Ewa Szarska, Łukasz Dziuda, Katarzyna Lorenz, Roman Łakomy, Tomasz Lepionka, Anna Anyżewska, Agnieszka Białek, Jerzy Bertrandt
Publikováno v:
Biology of Sport, Vol 38, Iss 4, Pp 767-776 (2021)
Peroxisome proliferator-activated receptors (PPARs) have unique functions in energy metabolism regulation but are also involved in regulation of the inflammatory process and obesity. The aim of this study was to analyse potential associations between
Externí odkaz:
https://doaj.org/article/1db10bd252f44f7b8adcbf58d421d119
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-8 (2021)
Abstract Background Genetic polymorphisms in the PPARD and NOS1AP is associated with type 2 diabetes mellitus (T2DM); however, there is no evidence about its impact on the therapeutic efficacy of nateglinide. This study was designed to investigate a
Externí odkaz:
https://doaj.org/article/f92d501db35445b38ef50844de64aaab
Akademický článek
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Autor:
Jinfang Song, Na Li, Ruonan Hu, Yanan Yu, Ke Xu, Hongwei Ling, Qian Lu, Tingting Yang, Tao Wang, Xiaoxing Yin
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundExenatide is a GLP-1R agonist that often exhibits considerable interindividual variability in therapeutic efficacy. However, there is no evidence about the impact of genetic variants in the PPARD on the therapeutic efficacy of exenatide. Th
Externí odkaz:
https://doaj.org/article/0c775ad8b1cd435c8a7c6f0e58dcde4a
Autor:
Isidora M. Keselj, Filip N. Bozic, Miodrag M. Vucinic, Dusan Lalosevic, Tatjana S. Kostic, Silvana A. Andric
Publikováno v:
Life, Vol 13, Iss 7, p 1457 (2023)
Mitochondrial dynamics plays a significant role in shaping the mitochondrial network and maintaining mitochondrial function. Imbalanced mitochondrial dynamics can cause mitochondrial dysfunction leading to a wide range of diseases/disorders. The aim
Externí odkaz:
https://doaj.org/article/b00b047f40bc411b96a0c8094354bce5