Dysregulated FOXO1 activity drives skeletal muscle intrinsic dysfunction in amyotrophic lateral sclerosis.

Autor: Zufiría M; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain., Pikatza-Menoio O; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; Stem Cells and Aging Group, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain., Garciandia-Arcelus M; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain., Bengoetxea X; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain., Jiménez A; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain., Elicegui A; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; Stem Cells and Aging Group, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain., Levchuk M; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain., Arnold-García O; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain., Ondaro J; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain., Iruzubieta P; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; Department of Neurology, Donostialdea Integrated Health Organization, Osakidetza Basque Health Service, 20014, Donostia/San Sebastian, Spain., Rodríguez-Gómez L; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain., Fernández-Pelayo U; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain., Muñoz-Oreja M; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; Department of Pediatrics, Faculty of Medicine and Nursery, University of the Basque Country UPV/EHU, 20014, Donostia/San Sebastian, Spain., Aiastui A; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; Cell Culture Platform, Biodonostia Health Research Institute, 20014, Donostia/San Sebastian, Spain., García-Verdugo JM; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; Laboratory of Comparative Neurobiology, Cavanilles Institute of Biodiversity and Evolutionary Biology, University of Valencia, 46980, Paterna, Spain.; Department of Cell Biology, Functional Biology and Physical Anthropology, University of Valencia, 46100, Burjassot, Spain., Herranz-Pérez V; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; Laboratory of Comparative Neurobiology, Cavanilles Institute of Biodiversity and Evolutionary Biology, University of Valencia, 46980, Paterna, Spain.; Department of Cell Biology, Functional Biology and Physical Anthropology, University of Valencia, 46100, Burjassot, Spain., Zulaica M; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain., Poza JJ; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; Department of Neurology, Donostialdea Integrated Health Organization, Osakidetza Basque Health Service, 20014, Donostia/San Sebastian, Spain., Ruiz-Onandi R; Department of Pathological Anatomy, Galdakao-Usansolo University Hospital, Osakidetza Basque Health Service, 48960, Galdakao, Spain.; Department of Medical-Surgical Specialties, Faculty of Medicine and Nursery, University of the Basque Country UPV/EHU, 48940, Leioa, Spain., Fernández-Torrón R; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; Department of Neurology, Donostialdea Integrated Health Organization, Osakidetza Basque Health Service, 20014, Donostia/San Sebastian, Spain., Espinal JB; Department of Neurology, Donostialdea Integrated Health Organization, Osakidetza Basque Health Service, 20014, Donostia/San Sebastian, Spain., Bonilla M; Department of Traumatology and Orthopedic Surgery, Donostialdea Integrated Health Organization, Osakidetza Basque Health Service, 20014, Donostia/San Sebastian, Spain., Lersundi A; Department of Traumatology and Orthopedic Surgery, Donostialdea Integrated Health Organization, Osakidetza Basque Health Service, 20014, Donostia/San Sebastian, Spain.; Department of Surgery, Faculty of Medicine and Nursery, University of the Basque Country UPV/EHU, 20014, Donostia/San Sebastián, Spain., Fernández-Eulate G; Department of Neurology, Donostialdea Integrated Health Organization, Osakidetza Basque Health Service, 20014, Donostia/San Sebastian, Spain.; Nord/Est/Ile-de-France Neuromuscular Reference Center, Institut de Myologie, Pitié-Salpêtrière Hospital, 75012, Paris, France.; Institut Necker-Enfants Malades, INSERM U1151, BioSPC (ED562), Université Paris Cité, 75015, Paris, France., Riancho J; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; Department of Neurology, Hospital de Sierrallana-IDIVAL, 39300, Torrelavega, Cantabria, Spain.; Department of Psychiatry and Medicine, Faculty of Medicine, University of Cantabria, 39011, Santander, Spain., Vallejo-Illarramendi A; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; Department of Pediatrics, Faculty of Medicine and Nursery, University of the Basque Country UPV/EHU, 20014, Donostia/San Sebastian, Spain., Holt IJ; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; IKERBASQUE - Basque Foundation for Science, 48009, Bilbao, Spain.; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Royal Free Campus, London, NW3 2PF, UK., Sáenz A; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain., Malfatti E; Université Paris Est Créteil, INSERM, IMRB, 94010, Créteil, France.; Hôpital Henri-Mondor, 94010, Créteil, France.; Paris Reference Center for Neuromuscular Disorders, APHP Henri Mondor University Hospital, 94010, Créteil, France., Duguez S; Personalised Medicine Centre, School of Medicine, Ulster University, Derry, BT47 6SB, UK.; Northern Ireland Center for Stratified Medicine, Biomedical Sciences Research Institute, Londonderry, UK., Blázquez L; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; IKERBASQUE - Basque Foundation for Science, 48009, Bilbao, Spain., López de Munain A; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; Department of Neurology, Donostialdea Integrated Health Organization, Osakidetza Basque Health Service, 20014, Donostia/San Sebastian, Spain.; Department of Neurosciences, Faculty of Medicine and Nursery, University of the Basque Country UPV/EHU, 20014, Donostia/San Sebastian, Spain.; Department of Medicine, Faculty of Health Sciences, University of Deusto, 48007, Bilbao, Spain.; Biodonostia Health Research Institute, 20014, Donostia/San Sebastian, Spain., Gerenu G; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; IKERBASQUE - Basque Foundation for Science, 48009, Bilbao, Spain.; Department of Physiology, Faculty of Medicine and Nursery, University of the Basque Country UPV/EHU, 48940, Leioa, Spain., Gil-Bea F; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain.; IKERBASQUE - Basque Foundation for Science, 48009, Bilbao, Spain.; Department of Health Sciences, Public University of Navarra (UPNA), 31006, Pamplona, Spain., Alonso-Martín S; Neurosciences Area, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain. sonia.alonsomartin@bio-gipuzkoa.eus.; CIBERNED, ISCIII (CIBER, Carlos III Institute, Spanish Ministry of Sciences and Innovation), 28031, Madrid, Spain. sonia.alonsomartin@bio-gipuzkoa.eus.; Stem Cells and Aging Group, Biogipuzkoa Health Research Institute, 20014, Donostia/San Sebastian, Spain. sonia.alonsomartin@bio-gipuzkoa.eus.

Publikováno v: Acta neuropathologica [Acta Neuropathol] 2024 Sep 16; Vol. 148 (1), pp. 43. Date of Electronic Publication: 2024 Sep 16.

Frequency and phenotypic spectrum of spinocerebellar ataxia 27B and other genetic ataxias in a Spanish cohort of late-onset cerebellar ataxia.

Autor: Iruzubieta P; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain.; CIBERNED Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas-Instituto de Salud Carlos III (CIBER-CIBERNED-ISCIII), Madrid, Spain.; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology London and The National Hospital for Neurology and Neurosurgery, University College London, London, UK., Pellerin D; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology London and The National Hospital for Neurology and Neurosurgery, University College London, London, UK.; Department of Neurology and Neurosurgery, Montreal Neurological Hospital and Institute, McGill University, Montreal, Quebec, Canada., Bergareche A; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain.; CIBERNED Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas-Instituto de Salud Carlos III (CIBER-CIBERNED-ISCIII), Madrid, Spain., Albajar I; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain., Mondragón E; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain.; CIBERNED Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas-Instituto de Salud Carlos III (CIBER-CIBERNED-ISCIII), Madrid, Spain., Vinagre A; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain.; CIBERNED Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas-Instituto de Salud Carlos III (CIBER-CIBERNED-ISCIII), Madrid, Spain., Fernández-Torrón R; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain.; CIBERNED Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas-Instituto de Salud Carlos III (CIBER-CIBERNED-ISCIII), Madrid, Spain., Moreno F; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain.; CIBERNED Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas-Instituto de Salud Carlos III (CIBER-CIBERNED-ISCIII), Madrid, Spain., Equiza J; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain., Campo-Caballero D; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain., Poza JJ; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain., Ruibal M; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain., Formica A; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain., Dicaire MJ; Department of Neurology and Neurosurgery, Montreal Neurological Hospital and Institute, McGill University, Montreal, Quebec, Canada., Danzi MC; Dr. John T. Macdonald Foundation Department of Human Genetics and John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, USA., Zuchner S; Dr. John T. Macdonald Foundation Department of Human Genetics and John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, USA., Croitoru I; CIBERNED Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas-Instituto de Salud Carlos III (CIBER-CIBERNED-ISCIII), Madrid, Spain., Ruiz M; Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Centre for Biomedical Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain., Schlüter A; Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Centre for Biomedical Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain., Casasnovas C; Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Neuromuscular Unit, Neurology Department, Hospital Universitari de Bellvitge, Universitat de Barcelona, Barcelona, Spain., Pujol A; Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Centre for Biomedical Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain.; Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain., Brais B; Department of Neurology and Neurosurgery, Montreal Neurological Hospital and Institute, McGill University, Montreal, Quebec, Canada.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada., Houlden H; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology London and The National Hospital for Neurology and Neurosurgery, University College London, London, UK., López de Munain A; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain.; CIBERNED Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas-Instituto de Salud Carlos III (CIBER-CIBERNED-ISCIII), Madrid, Spain., Ruiz-Martínez J; Department of Neurology, Donostia University Hospital, Biodonostia Health Research Institute, Donostia-San Sebastián, Spain.; CIBERNED Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas-Instituto de Salud Carlos III (CIBER-CIBERNED-ISCIII), Madrid, Spain.

Publikováno v: European journal of neurology [Eur J Neurol] 2023 Dec; Vol. 30 (12), pp. 3828-3833. Date of Electronic Publication: 2023 Aug 27.

Proposed Recommendations for the Management of Depression in Adults with Epilepsy: An Expert Consensus.

Autor: Villanueva V; Refractory Epilepsy Unit, Neurology Service, Hospital Universitario y Politécnico la Fe, Valencia, Spain., Artal J; Psychiatry Department, Hospital Universitario Marqués de Valdecilla, Av. de Valdecilla, 25, 39008, Santander, Spain. jesusartalsimon@gmail.com., Cabeza-Alvarez CI; Neurology Department, Hospital Universitario de Toledo, Toledo, Spain., Campos D; Neurology Department, University Clinical Hospital of Valladolid, Valladolid, Spain., Castillo A; Neurology Department, Consorcio Hospital General Universitario Valencia, Valencia, Spain., Flórez G; Psychiatry Department, Addiction Treatment Unit, Orense, Spain., Franco-Martin M; Psychiatry Department, Zamora Hospital (Complejo Asistencial de Zamora), Zamora, Spain., García-Portilla MP; Psychiatry Department, University of Oviedo, ISPA, CIBERSAM, INEUROPA, and Mental Health Services of Principality of Asturias, Oviedo, Spain., Giráldez BG; Neurology Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain., Gotor F; Psychiatry Department, School of Medicine, University Hospital Virgen del Rocio, Seville, Spain., Gutiérrez-Rojas L; Psychiatry Department, Hospital San Cecilio, Granada, Spain., Albanell AM; Neurology Department, Hospital de Girona-Salt, Salt, Spain., Paniagua G; Psychiatry Department, University of Oviedo, Oviedo, Spain.; Mental Health Services of Principado de Asturias, SESPA, Oviedo, Spain., Pintor L; Psychiatry Department, Hospital Clínico of Barcelona, Barcelona, Spain., Poza JJ; Neurology Department, Hospital Universitario Donostia, Donostia, Spain., Rubio-Granero T; Psychiatry Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain., Toledo M; Epilepsy Unit, Vall D'Hebron University Hospital, Barcelona, Spain., Tortosa-Conesa D; Neurology Department, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain., Rodríguez-Uranga J; Neurology Department, Centro de Neurología Avanzada (CNA), Seville, Spain., Bobes J; Medicine-Psychiatry, Universidad de Oviedo, Oviedo, Spain.

Publikováno v: Neurology and therapy [Neurol Ther] 2023 Apr; Vol. 12 (2), pp. 479-503. Date of Electronic Publication: 2023 Jan 24.

Melatonin in sleep disorders

Autor: Poza JJ, Pujol M, Ortega-Albás JJ, Romero O, en representación del Grupo de estudio de insomnio de la Sociedad Española de Su

Publikováno v: NEUROLOGIA
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)

Melatonin is the main hormone involved in the control of the sleep-wake cycle. It is easily synthesisable and can be administered orally, which has led to interest in its use as a treatment for insomnia. Moreover, as production of the hormone decreas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::d00d89eb335b84e9a393bd087730a94f
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=3151

ALS: A bucket of genes, environment, metabolism and unknown ingredients

Autor: Zufiria, M, Gil-Bea, FJ, Fernandez-Torron, R, Poza, JJ, Munoz-Blanco, JL, Rojas-Garcia, R, Riancho, J, de Munain, AL

Publikováno v: PROGRESS IN NEUROBIOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

The scientific scenario of amyotrophic lateral sclerosis (ALS) has dramatically changed since TDP-43 aggregates were discovered in 2006 as the main component of the neuronal inclusions seen in the disease, and more recently, when the implication of C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::6f2e86a182d2695fc705b706242cf2db
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=7184