THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview

Autor: Alexander, Stephen PH, Kelly, Eamonn, Marrion, Neil V, Peters, John A, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Buneman, O Peter, Cidlowski, John A, Christopoulos, Arthur, Davenport, Anthony P, Fabbro, Doriano, Spedding, Michael, Striessnig, Jörg, Davies, Jamie A, Abbracchio, M. -P., Aldrich, R., Al-Hosaini, K., Arumugam, T. V., Attali, B., Bäck, M., Barnes, N. M., Bathgate, R., Beart, P. M., Becirovic, E., Bettler, B., Biel, M., Birdsall, N. J., Blaho, V., Boison, D., Bräuner-osborne, H., Bröer, S., Bryant, C., Burnstock, G., Calo, G., Catterall, W. A., Ceruti, S., Chan, S. L., Chandy, K. G., Chazot, P., Chiang, N., Chun, J. J., Chung, J. -J., Clapham, D. E., Clapp, L., Connor, M. A., Cox, H. M., Davies, P., Dawson, P. A., Decaen, P., Dent, G., Doherty, P., Douglas, S. D., Dubocovich, M. L., Fong, T. M., Fowler, C. J., Frantz, A., Fuller, P., Fumagalli, M., Futerman, A. H., Gainetdinov, R. R., Gershengorn, M. A., Goldin, A., Goldstein, S. A. N., Goudet, C., Gregory, K., Grissmer, S., Gundlach, A. L., Hagenbuch, B., Hamann, J., Hammond, J. R., Hancox, J. C., Hanson, J., Hanukoglu, I., Hay, D. L., Hobbs, A. J., Hollenberg, A. N., Holliday, N. D., Hoyer, D., Ijzerman, A. P., Inui, K. I., Irving, A. J., Ishii, S., Jacobson, K. A., Jan, L. Y., Jarvis, M. F., Jensen, R., Jockers, R., Kaczmarek, L. K., Kanai, Y., Karnik, S., Kellenberger, S., Kemp, S., Kennedy, C., Kerr, I. D., Kihara, Y., Kukkonen, J., Larhammar, D., Leach, K., Lecca, D., Leeman, S., Leprince, J., Lolait, S. J., Macewan, D., Maguire, J. J., Marshall, F., Mazella, J., Mcardle, C. A., Michel, M. C., Miller, L. J., Mitolo, V., Mizuno, H., Monk, P. N., Mouillac, B., Murphy, P. M., Nahon, J. -L., Nerbonne, J., Nichols, C. G., Norel, X., Offermanns, S., Palmer, L. G., Panaro, M. A., Papapetropoulos, A., Perez-reyes, E., Pertwee, R. G., Pintor, S., Pisegna, J. R., Plant, L. D., Poyner, D. R., Prossnitz, E. R., Pyne, S., Ramachandran, R., Ren, D., Rondard, P., Ruzza, C., Sackin, H., Sanger, G., Sanguinetti, M. C., Schild, L., Schiöth, H., Schulte, G., Schulz, S., Segaloff, D. L., Serhan, C. N., Singh, K. D., Slesinger, P. A., Snutch, T. P., Sobey, C. G., Stewart, G., Stoddart, L. A., Summers, R. J., Szabo, C., Thwaites, D., Toll, L., Trimmer, J. S., Tucker, S., Vaudry, H., Verri, T., Vilargada, J. -P., Waldman, S. A., Ward, D. T., Waxman, S. G., Wei, A. D., Willars, G. B., Wong, S. S., Woodruff, T. M., Wulff, H., Ye, R. D., Yung, Y., Zajac, J. -M.

The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where availabl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4034::6589a44220ffa82d64b3fcc5f3dceb7a
https://hdl.handle.net/11587/419455

Modulation of Glucagon Receptor Pharmacology by Receptor Activity-modifying Protein-2 (RAMP2)

Autor: Weston, C., Lu, J., Li, N., Barkan, K., Richards, G.O., Roberts, D.J., Skerry, T.M., Poyner, D., Pardamwar, M., Reynolds, C.A., Dowell, S.J., Willars, G.B., Ladds, G.

The glucagon and glucagon-like peptide-1 (GLP-1) receptors\ud play important, opposing roles in regulating blood glucose levels.\ud Consequently, these receptors have been identified as targets\ud for novel diabetes treatments. However, drugs acting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::52a6bc113716ba31c971de6922897a45

Receptor activity modifying proteins (RAMPs) interact with the VPAC 2 receptor and CRF 1 receptors and modulate their function: RAMP interactions with VPAC2and CRF1receptors

Autor: Barwell, J., Caron, K. M., Lindmark, H., Poyner, D. R., Wootten, D., Drmota, T., Kadmiel, M., Willcockson, H.

Although it is established that the receptor activity modifying proteins (RAMPs) can interact with a number of GPCRs, little is known about the consequences of these interactions. Here the interaction of RAMPs with the glucagon-like peptide 1 recepto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::865ce9d8ac102c70ac3c65729f197a9d

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