Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Poyil Pratheeshkumar"'
Autor:
Abdul K. Siraj, Poyil Pratheeshkumar, Sasidharan Padmaja Divya, Sandeep Kumar Parvathareddy, Khadija A. Alobaisi, Saravanan Thangavel, Sarah Siraj, Ismail A. Al-Badawi, Fouad Al-Dayel, Khawla S. Al-Kuraya
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy. Despite current therapeutic and surgical options, advanced EOC shows poor prognosis. Identifying novel molecular therapeutic targets is highly needed in the management of EO
Externí odkaz:
https://doaj.org/article/626fc49ce8784d21a03007be373b2408
Autor:
Abdul K. Siraj, Sandeep Kumar Parvathareddy, Poyil Pratheeshkumar, Sasidharan Padmaja Divya, Saeeda Omer Ahmed, Roxanne Melosantos, Rafia Begum, Rica Micaela J.A. Concepcion, Nasser Al-Sanea, Luai H Ashari, Alaa Abduljabbar, Fouad Al-Dayel, Khawla S. Al-Kuraya
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 121, Iss , Pp 109572- (2020)
Colorectal Cancer (CRC) is highly heterogeneous for which prognosis is dependent mainly on clinical staging. There is a need to stratify subpopulations of CRC on molecular basis to better predict outcome and therapy response. Truncating mutations in
Externí odkaz:
https://doaj.org/article/bd624afc3e96466f9230488a05b60eb3
Autor:
Azhar R. Hussain, Abdul Khalid Siraj, Maqbool Ahmed, Rong Bu, Poyil Pratheeshkumar, Alanood M. Alrashed, Zeeshan Qadri, Dahish Ajarim, Fouad Al-Dayel, Shaham Beg, Khawla S. Al-Kuraya
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-13 (2017)
Abstract Background Breast cancer is the most common cancer in females and is ranked second in cancer-related deaths all over the world in women. Despite improvement in diagnosis, the survival rate of this disease has still not improved. X-linked Inh
Externí odkaz:
https://doaj.org/article/a0f64280cf4344bcbfc09b5c2ba7c060
Autor:
Abdul K. Siraj, Sandeep Kumar Parvathareddy, Poyil Pratheeshkumar, Sasidharan Padmaja Divya, Saif S. Al-Sobhi, Fouad Al-Dayel, Khawla S. Al-Kuraya
Publikováno v:
Cancers, Vol 13, Iss 3, p 555 (2021)
PD-L1 inhibition is a promising therapeutic target whose efficacy has been demonstrated in several cancers. Immunohistochemistry was performed to assess PD-L1 protein expression in PTC. We further conducted in vitro analysis to investigate the role o
Externí odkaz:
https://doaj.org/article/504d1f95cf444a0398ca0c4f2c9c98c0
Autor:
Poyil Pratheeshkumar, Abdul K. Siraj, Sasidharan Padmaja Divya, Sandeep Kumar Parvathareddy, Khadija Alobaisi, Saif S. Al-Sobhi, Fouad Al-Dayel, Khawla S. Al-Kuraya
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 504 (2021)
Chromodomain-helicase-DNA-binding protein 4 (CHD4), a core subunit of the nucleosome remodeling and deacetylation (NuRD) complex is highly expressed in several cancers. However, its role in the pathogenesis and progression of papillary thyroid carcin
Externí odkaz:
https://doaj.org/article/4514f115e01e476190d9f776004c5dd2
Autor:
Poyil Pratheeshkumar, Abdul K. Siraj, Sasidharan Padmaja Divya, Sandeep Kumar Parvathareddy, Sarah Siraj, Roxanne Diaz, Rafia Begum, Saif S. Al-Sobhi, Fouad Al-Dayel, Khawla S. Al-Kuraya
Publikováno v:
Cancers, Vol 13, Iss 2, p 185 (2021)
The Krüppel-like factor 5 (KLF5), a zinc-finger transcriptional factor, is highly expressed in several solid tumors, but its role in PTC remains unclear. We investigated the expression of KLF5 protein in a large cohort of PTC patient samples and exp
Externí odkaz:
https://doaj.org/article/f6196e09150c4ba1bf769ca52f09ed40
Autor:
Poyil Pratheeshkumar, Amit Budhraja, Young-Ok Son, Xin Wang, Zhuo Zhang, Songze Ding, Lei Wang, Andrew Hitron, Jeong-Chae Lee, Mei Xu, Gang Chen, Jia Luo, Xianglin Shi
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47516 (2012)
Angiogenesis is a crucial step in the growth and metastasis of cancers, since it enables the growing tumor to receive oxygen and nutrients. Cancer prevention using natural products has become an integral part of cancer control. We studied the antiang
Externí odkaz:
https://doaj.org/article/346edac5fdf24e2598b3edc3d3c9f9ca
Autor:
Poyil Pratheeshkumar, Young-Ok Son, Amit Budhraja, Xin Wang, Songze Ding, Lei Wang, Andrew Hitron, Jeong-Chae Lee, Donghern Kim, Sasidharan Padmaja Divya, Gang Chen, Zhuo Zhang, Jia Luo, Xianglin Shi
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52279 (2012)
Angiogenesis, the formation of new blood vessels from pre-existing vascular beds, is essential for tumor growth, invasion, and metastasis. Luteolin is a common dietary flavonoid found in fruits and vegetables. We studied the antiangiogenic activity o
Externí odkaz:
https://doaj.org/article/bfab9796e7f14f9c9ff23f34a04a9bff
Autor:
Turcios, Lilia, Vilchez, Valery, Acosta, Luis F., Poyil, Pratheeshkumar, Butterfield, David Allan, Mitov, Mihail, Marti, Francesc, Gedaly, Roberto
Publikováno v:
In Digestive and Liver Disease June 2017 49(6):697-704
Autor:
Khawla S. Al-Kuraya, Fouad Al-Dayel, Samar Al-Homoud, Alaa Abduljabbar, Luai H. Ashari, Nasser Al-Sanea, Saravanan Thangavel, Yan Kong, Tariq Masoodi, Rong Bu, Sandeep Kumar Parvathareddy, Sasidharan Padmaja Divya, Poyil Pratheeshkumar, Abdul K. Siraj
Correlation of Smad4 mutation with clinico-pathological parameters in colorectal carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30128fa61f718f6a480b67b4ebd6c231
https://doi.org/10.1158/1535-7163.22506166.v1
https://doi.org/10.1158/1535-7163.22506166.v1