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Analysis of the combined effect of rs699 and rs5051 on angiotensinogen expression and hypertension.

Autor: Powell NR; Division of Clinical Pharmacology, Department of Medicine School of Medicine, Indiana University Indianapolis Indiana USA., Shugg T; Division of Clinical Pharmacology, Department of Medicine School of Medicine, Indiana University Indianapolis Indiana USA., Leighty J; Division of Clinical Pharmacology, Department of Medicine School of Medicine, Indiana University Indianapolis Indiana USA., Martin M; Department of Pharmacology and Toxicology School of Medicine, Indiana University Indianapolis Indiana USA., Kreutz RP; Department of Cardiology School of Medicine, Krannert Institute of Cardiology, Indiana University Indianapolis Indiana USA., Eadon MT; Division of Nephrology, Department of Medicine School of Medicine, Indiana University Indianapolis Indiana USA.; Department of Medical and Molecular Genetics School of Medicine, Indiana University Indianapolis Indiana USA., Lai D; Department of Medical and Molecular Genetics School of Medicine, Indiana University Indianapolis Indiana USA., Lu T; Department of Pharmacology and Toxicology School of Medicine, Indiana University Indianapolis Indiana USA., Skaar TC; Division of Clinical Pharmacology, Department of Medicine School of Medicine, Indiana University Indianapolis Indiana USA.; Department of Medical and Molecular Genetics School of Medicine, Indiana University Indianapolis Indiana USA.

Publikováno v: Chronic diseases and translational medicine [Chronic Dis Transl Med] 2023 Dec 26; Vol. 10 (2), pp. 102-117. Date of Electronic Publication: 2023 Dec 26 (Print Publication: 2024).

Clinically important alterations in pharmacogene expression in histologically severe nonalcoholic fatty liver disease.

Autor: Powell NR; Indiana University School of Medicine, Department of Medicine, Division of Clinical Pharmacology, Indianapolis, IN, USA., Liang T; Indiana University School of Medicine, Department of Medicine, Division of Gastroenterology Hepatology, Indianapolis, IN, USA., Ipe J; Indiana University School of Medicine, Department of Medicine, Division of Clinical Pharmacology, Indianapolis, IN, USA., Cao S; Indiana University School of Medicine, Department of Medicine, Division of Gastroenterology Hepatology, Indianapolis, IN, USA., Skaar TC; Indiana University School of Medicine, Department of Medicine, Division of Clinical Pharmacology, Indianapolis, IN, USA., Desta Z; Indiana University School of Medicine, Department of Medicine, Division of Clinical Pharmacology, Indianapolis, IN, USA., Qian HR; Eli Lilly and Company, Indianapolis, IN, USA., Ebert PJ; Eli Lilly and Company, Indianapolis, IN, USA., Chen Y; Eli Lilly and Company, Indianapolis, IN, USA., Thomas MK; Eli Lilly and Company, Indianapolis, IN, USA., Chalasani N; Indiana University School of Medicine, Department of Medicine, Division of Gastroenterology Hepatology, Indianapolis, IN, USA. nchalasa@iu.edu.

Publikováno v: Nature communications [Nat Commun] 2023 Mar 17; Vol. 14 (1), pp. 1474. Date of Electronic Publication: 2023 Mar 17.

Quantification of spatial pharmacogene expression heterogeneity in breast tumors.

Autor: Powell NR; Department of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Silvola RM; Department of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Howard JS; Department of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Badve S; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Skaar TC; Department of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Ipe J; Department of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Publikováno v: Cancer reports (Hoboken, N.J.) [Cancer Rep (Hoboken)] 2023 Jan; Vol. 6 (1), pp. e1686. Date of Electronic Publication: 2022 Jul 30.

Life-Threatening Docetaxel Toxicity in a Patient With Reduced-Function CYP3A Variants: A Case Report.

Autor: Powell NR; Department of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, IN, United States., Shugg T; Department of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, IN, United States., Ly RC; Department of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, IN, United States., Albany C; Department of Medicine, Division of Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN, United States., Radovich M; Department of Medicine, Division of Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN, United States., Schneider BP; Department of Medicine, Division of Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN, United States., Skaar TC; Department of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, IN, United States.

Publikováno v: Frontiers in oncology [Front Oncol] 2022 Jan 31; Vol. 11, pp. 809527. Date of Electronic Publication: 2022 Jan 31 (Print Publication: 2021).