MicroRNA let-7b enhances spinal cord nociceptive synaptic transmission and induces acute and persistent pain through neuronal and microglial signaling.

Autor: Chen O; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University Medical Center, Durham, NC, United States.; Department of Cell Biology, Duke University Medical Center, Durham, NC, United States., Jiang C; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University Medical Center, Durham, NC, United States., Berta T; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University Medical Center, Durham, NC, United States.; Department of Anesthesiology, Pain Research Center, University of Cincinnati Medical Center, Cincinnati, OH, United States., Powell Gray B; Department of Surgery, Duke Cancer Institute, Duke University Medical Center, Durham, NC, United States.; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Furutani K; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University Medical Center, Durham, NC, United States., Sullenger BA; Department of Surgery, Duke Cancer Institute, Duke University Medical Center, Durham, NC, United States., Ji RR; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University Medical Center, Durham, NC, United States.; Department of Cell Biology, Duke University Medical Center, Durham, NC, United States.; Department of Neurobiology, Duke University Medical Center, Durham, NC, United States.

Publikováno v: Pain [Pain] 2024 Aug 01; Vol. 165 (8), pp. 1824-1839. Date of Electronic Publication: 2024 Mar 06.

Tunable cytotoxic aptamer-drug conjugates for the treatment of prostate cancer.

Autor: Powell Gray B; Department of Surgery, Duke University Medical Center, Durham, NC 27710., Kelly L; Department of Surgery, Duke University Medical Center, Durham, NC 27710.; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461., Ahrens DP; Research and Development Division, b3 bio, inc., Durham, NC 27709., Barry AP; Research and Development Division, b3 bio, inc., Durham, NC 27709., Kratschmer C; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461., Levy M; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461., Sullenger BA; Department of Surgery, Duke University Medical Center, Durham, NC 27710; bruce.sullenger@duke.edu.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 May 01; Vol. 115 (18), pp. 4761-4766. Date of Electronic Publication: 2018 Apr 16.