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Replenishing Age-Related Decline of IRAK-M Expression in Retinal Pigment Epithelium Attenuates Outer Retinal Degeneration.

Autor: Liu J; Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Copland DA; Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Clare AJ; Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Gorski M; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Richards BT; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City, Utah, United States., Scott L; Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Theodoropoulou S; Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Greferath U; Department of Anatomy and Physiology, University of Melbourne, Victoria, Australia., Cox K; Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Bell OH; Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Ou K; Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Powell JLB; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Wu J; Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Robles LM; School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom., Li Y; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Nicholson LB; Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom., Coffey PJ; Institute of Ophthalmology, University College London, London, United Kingdom., Fletcher EL; Department of Anatomy and Physiology, University of Melbourne, Victoria, Australia., Guymer R; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, Melbourne, Australia., Radeke MJ; Neuroscience Research Institute, University of California, Santa Barbara, California, United States., Heid IM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Hageman GS; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City, Utah, United States., Chan YK; Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts, United States., Dick AD; Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.; Institute of Ophthalmology, University College London, London, United Kingdom.; National Institute for Health Research Biomedical Research Centre, Moorfields Eye Hospital, London, United Kingdom.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 29. Date of Electronic Publication: 2023 Sep 29.