SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

Autor: Achdout, Hagit, Aimon, Anthony, Bar-David, Elad, Barr, Haim, Ben-Shmuel, Amir, Bennett, James, Boby, Melissa L., Borden, Bruce, Bowman, Gregory R., Brun, Juliane, BVNBS, Sarma, Calmiano, Mark, Carbery, Anna, Cattermole, Emma, Chernychenko, Eugene, Choder, John D., Clyde, Austin, Coffland, Joseph E., Cohen, Galit, Cole, Jason, Contini, Alessandro, Cox, Lisa, Cvitkovic, Milan, Dias, Alex, Donckers, Kim, Dotson, David L., Douangamath, Alica, Duberstein, Shirly, Dudgeon, Tim, Dunnett, Louise, Eastman, Peter K., Erez, Noam, Eyermann, Charles J., Fairhead, Mike, Fate, Gwen, Fearon, Daren, Federov, Oleg, Ferla, Matteo, Fernandes, Rafaela S., Ferrins, Lori, Foster, Richard, Foster, Holly, Gabizon, Ronen, Garcia-Sastre, Adolfo, Gawriljuk, Victor O., Gehrtz, Paul, Gileadi, Carina, Giroud, Charline, Glass, William G., Glen, Robert, Itai glinert, Godoy, Andre S., Gorichko, Marian, Gorrie-Stone, Tyler, Griffen, Ed J., Hart, Storm Hassell, Heer, Jag, Henry, Micheal, Hill, Michelle, Horrell, Sam, Hurley, Matthew F.D., Israely, Tomer, Jajack, Andrew, Jnoff, Eric, Jochmans, Dirk, John, Tobias, De Jonghe, Steven, Kantsadi, Anastassia L., Kenny, Peter W., Kiappes, J.L., Koekemoer, Lizbe, Kovar, Boris, Krojer, Tobias, Lee, Alpha A., Lefker, Bruce A., Levy, Haim, London, Nir, Lukacik, Petra, Macdonald, Hannah Bruce, Maclean, Beth, Malla, Tika R., Matviiuk, Tatiana, McCorkindale, Willam, McGovern, Briana L., Melamed, Sharon, Michurin, Oleg, Mikolajek, Halina, Milne, Bruce F., Morris, Aaron, Morris, Garret M., Morwitzer, Melody Jane, Moustakas, Demetri, Nakamura, Aline M., Neto, Jose Brandao, Neyts, Johan, Nguyen, Luong, Noske, Gabriela D., Oleinikovas, Vladas, Oliva, Glaucius, Overheul, Gijs J., Owen, David, Psenak, Vladimir, Pai, Ruby, Pan, Jin, Paran, Nir, Perry, Benjamin, Pingle, Maneesh, Pinjari, Jakir, Politi, Boaz, Powell, Ailsa, Puni, Reut, Rangel, Victor L., Reddi, Ranbabu N., Reid, St Patrick, Resnick, Efrat, Ripka, Emily Grace, Robinson, Matthew C., Robinson, Ralph P., Rodriguez-Guerra, Jaime, Rosales, Romel, Rufa, Dominic, Schofield, Chris, Shafeev, Mikhail, Shaikh, Aarif, Shi, Jiye, Shurrush, Khriesto, Sing, Sukrit, Sittner, Assa, Skyner, Rachael, Smalley, Adam, Smilova, Mihaela D., Solmesky, Leonardo J., Spencer, John, Strain-Damarell, Claire, Swamy, Vishwanath, Tamir, Hadas, Tennant, Rachael, Thompson, Warren, Thompson, Andrew, Tomasia, Susana, Tumber, Anthony, Vakonakis, Ioannis, van Rij, Ronald P., van Geel, Laura, Varghese, Finny S., Vaschetto, Mariana, Vitner, Einat B., Voelz, Vincent, Volkamer, Andra, von Delft, Frank, von Delft, Annette, Walsh, Martin, Ward, Walter, Weatherall, Charlie, Weiss, Shay, White, Kris M., Wild, Conor Francis, Wittmann, Matthew, Wright, Nathan, Yahalom-Ronen, Yfat, Zaidmann, Daniel, Zidane, Hadeer, Zitzmann, Nicole, Jansen, Jitske, Reimer, Katharina C., Nagai, James S., de Beer, Marit, Roverts, Rona, Daviran, Deniz, Fermin, Liline A.S., Willemsen, Brigith, Beukenboom, Marcel, Djudjaj, Sonja, von Stillfried, Saskia, van Eijk, Larissa E., Mastik, Mirjam, Bulthuis, Marian, Dunnen, Wilfred den, van Goor, Harry, Hillebrands, Jan-Luuk, Triana, Sergio H., Alexandrov, Theodore, Timm, Marie-Cherelle, van den Berge, Bartholomeus T., van den Broek, Martijn, Nlandu, Quincy, Heijnert, Joelle, Bindels, Eric M.J., Hoogenboezem, Remco M., Mooren, Fieke, Kuppe, Christoph, Miesen, Pascal, Grünberg, Katrien, Ijzermans, Ties, Steenbergen, Eric J., Czogalla, Jan, Schreuder, Michiel F., Sommerdijk, Nico, Akiva, Anat, Boor, Peter, Puelles, Victor G., Floege, Jürgen, Huber, Tobias B., Costa, Ivan G., Schneider, Rebekka K., Smeets, Bart, Kramann, Rafael

Publikováno v: In Cell Stem Cell 3 February 2022 29(2):217-231

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

Autor: Schuller, Marion, Correy, Galen J, Gahbauer, Stefan, Fearon, Daren, Wu, Taiasean, Díaz, Roberto Efraín, Young, Iris D, Carvalho Martins, Luan, Smith, Dominique H, Schulze-Gahmen, Ursula, Owens, Tristan W, Deshpande, Ishan, Merz, Gregory E, Thwin, Aye C, Biel, Justin T, Peters, Jessica K, Moritz, Michelle, Herrera, Nadia, Kratochvil, Huong T, QCRG Structural Biology Consortium, Aimon, Anthony, Bennett, James M, Brandao Neto, Jose, Cohen, Aina E, Dias, Alexandre, Douangamath, Alice, Dunnett, Louise, Fedorov, Oleg, Ferla, Matteo P, Fuchs, Martin R, Gorrie-Stone, Tyler J, Holton, James M, Johnson, Michael G, Krojer, Tobias, Meigs, George, Powell, Ailsa J, Rack, Johannes Gregor Matthias, Rangel, Victor L, Russi, Silvia, Skyner, Rachael E, Smith, Clyde A, Soares, Alexei S, Wierman, Jennifer L, Zhu, Kang, O'Brien, Peter, Jura, Natalia, Ashworth, Alan, Irwin, John J, Thompson, Michael C, Gestwicki, Jason E, von Delft, Frank, Shoichet, Brian K, Fraser, James S, Ahel, Ivan

Publikováno v: Science advances, vol 7, iss 16

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) macrodomain within the nonstructural protein 3 counteracts host-mediated antiviral adenosine diphosphate-ribosylation signaling. This enzyme is a promising antiviral target because cata

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::8b0f926904f003bc747848f51e89322a
https://escholarship.org/uc/item/9499n6d3

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