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Piezo1 forms a mechanically activated calcium-permeable nonselective cation channel that is functionally important in many cell types. Structural data exist for C-terminal regions, but we lack information about N-terminal regions and how the entire c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::e0372684439e0f4bc8589ec8a9914d56
https://eprints.whiterose.ac.uk/170766/12/1-s2.0-S0006349521001363-main.pdf
https://eprints.whiterose.ac.uk/170766/12/1-s2.0-S0006349521001363-main.pdf
Autor:
Carr, G, Barrese, V, Stott, JB, Povstyan, OV, Jepps, TA, Figueiredo, HB, Zheng, D, Jamshidi, Y, Greenwood, IA
Publikováno v:
Carr, G, Barrese, V, Stott, J B, Povstyan, O V, Jepps, T A, Figueiredo, H B, Zheng, D, Jamshidi, Y & Greenwood, I A 2016, ' MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension ', Cardiovascular Research, vol. 112, pp. 581-589 . https://doi.org/10.1093/cvr/cvw177
Cardiovascular Research
Cardiovascular Research
AIMS: Kv7.4, a voltage-dependent potassium channel expressed throughout the vasculature, controls arterial contraction and is compromised in hypertension by an unknown mechanism. MicroRNAs (miRs) are post-transcriptional regulators of protein product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::01ef56229ce99b18ed26d98a22c54f15
https://curis.ku.dk/portal/da/publications/microrna153-targeting-of-kcnq4-contributes-to-vascular-dysfunction-in-hypertension(bc77a153-e234-4fd7-beb0-f63780e4fae9).html
https://curis.ku.dk/portal/da/publications/microrna153-targeting-of-kcnq4-contributes-to-vascular-dysfunction-in-hypertension(bc77a153-e234-4fd7-beb0-f63780e4fae9).html
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Autor:
Zholos AV; Taras Shevchenko National University of Kyiv, Kyiv, Ukraine., Greenwood IA; St George's University of London, London, UK., Lang RJ; Monash University, Melbourne, Victoria, Australia., Benham CD; University of Hertfordshire, Hatfield, UK., Aaronson PI; King's College London, London, UK., Garland CJ; University of Oxford, Oxford, UK., Weston AH; University of Manchester, Manchester, UK., Prestwich SA; Horsham, UK., Gordienko DV; Inserm U1003, Université de Lille, Villeneuve d'Ascq, France., Povstyan OV; University of Leeds, Leeds, UK., Zhang H; Hebei Medical University, Shijiazhuang, China., Clapp LH; University College London, London, UK., Pucovsky V; European Medicines Agency, Amsterdam, The Netherlands., Tare M; Monash University Melbourne, Melbourne, Victoria, Australia., Fenech CJ; CNRS UMR6265 - CSGA, Dijon, France., Unno T; Gifu University, Gifu, Japan., Muraki K; Aichi-Gakuin University, Nagoya, Japan., Shi J; University of Leeds, Leeds, UK., Hughes AD; University College London, London, UK., Halstead TK; University of York, York, UK., Beech DJ; University of Leeds, Leeds, UK.
Publikováno v:
The Journal of physiology [J Physiol] 2024 Aug; Vol. 602 (15), pp. 3601-3604. Date of Electronic Publication: 2024 Jun 28.
Autor:
Parsonage G; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK., Cuthbertson K; School of Chemistry, University of Leeds, Leeds, UK., Endesh N; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK., Murciano N; Nanion Technologies GmbH, Munich, Germany.; Theoretical Medicine and Biosciences, Saarland University, Homburg, Germany., Hyman AJ; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK., Revill CH; School of Chemistry, University of Leeds, Leeds, UK., Povstyan OV; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK., Chuntharpursat-Bon E; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK., Debant M; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK., Ludlow MJ; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK., Futers TS; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK., Lichtenstein L; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK., Kinsella JA; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK., Bartoli F; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK., Rotordam MG; Nanion Technologies GmbH, Munich, Germany.; Theoretical Medicine and Biosciences, Saarland University, Homburg, Germany., Becker N; Nanion Technologies GmbH, Munich, Germany., Brüggemann A; Nanion Technologies GmbH, Munich, Germany., Foster R; School of Chemistry, University of Leeds, Leeds, UK., Beech DJ; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK.
Publikováno v:
British journal of pharmacology [Br J Pharmacol] 2023 Aug; Vol. 180 (16), pp. 2039-2063. Date of Electronic Publication: 2023 Jan 31.